Results 141 to 150 of about 1,425,061 (397)
Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism
Advanced Science, EarlyView.Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu +16 morewiley +1 more sourceUpdate on Adjuvant Chemotherapy for Early Breast Cancer
Breast Cancer: Basic and Clinical Research, 2014 Breast cancer is the second most common cancer in women worldwide. Although most women are diagnosed with early breast cancer, a substantial number recur due to persistent micro-metastatic disease. Systemic adjuvant chemotherapy improves outcomes and has Murtuza M. Rampurwala, Gabrielle B. Rocque, Mark E. Burkard +2 moredoaj +1 more sourceEffectiveness of postoperative radiotherapy after radical cystectomy for locally advanced bladder cancer [PDF]
, 2019 BACKGROUND: Local-regional failure (LF) for locally advanced bladder cancer (LABC) after radical cystectomy (RC) is common even with chemotherapy and is associated with high morbidity/mortality.Andriole, Gerald L, Arora, Vivek, Baumann, Brian C, Bullock, Arnold, DeWees, Todd A, et al,, Figenshau, Robert S, Fischer-Valuck, Benjamin W, Gay, Hiram A, Grubb, Robert L, Kim, Eric, Knoche, Eric M, Michalski, Jeff M, Pachynski, Russell K, Roth, Bruce J, Smith, Zachary L +15 morecore +2 more sourcesA multicenter, phase 3, randomized trial of concurrent chemoradiotherapy plus adjuvant chemotherapy versus radiotherapy alone in patients with regionally advanced nasopharyngeal carcinoma: 10‐year outcomes for efficacy and toxicity [PDF]
, 2017 Anne W.M. Lee, Stewart Y. Tung, Wai Tong Ng, Victor Lee, Roger K.C. Ngan, Cheuk‐Wai Choi, Lucy Chan, Lillian L. Siu, Alice Ng, To Wai Leung, Harry Yiu, Brian O’Sullivan, Rick Chappell +12 moreopenalex +1 more sourceA Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste +5 morewiley +1 more sourceA randomised study of adjuvant chemotherapy after mantle radiotherapy in supradiaphragmatic Hodgkin's disease PS IA-IIB: A report from the Manchester lymphoma group [PDF]
, 1984 Heather Anderson, D.P. Deakin, John Wagstaff, Judy Jones, Ian Todd, P M Wilkinson, R.D. James, William P. Steward, G. Blackledge, J H Scarffe, D. Crowther +10 moreopenalex +1 more sourceHomoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death
Advanced Science, EarlyView.Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen +12 morewiley +1 more sourceAdjuvant chemotherapy
European Journal of Cancer Supplements, 2013 David B. Abrams, J. Rick Turner, Linda C. Baumann, Alyssa Karel, Susan E. Collins, Katie Witkiewitz, Terry Fulmer, Molly L. Tanenbaum, Persis Commissariat, Elyse Kupperman, Rachel N. Baek, Jeffrey S. Gonzalez, Nicole Brandt, Rachel Flurie, Jennifer Heaney, Christopher Kline, Linda Carroll, Jane Upton, Patrícia Cardoso Buchain, Adriana Dias Barbosa Vizzotto, Alexandra Martini de Oliveira, Tania C. T. Ferraz Alves, Quirino Cordeiro, Lorenzo Cohen, M. Kay Garcia, Amy Jo Marcano-Reik, Siqin Ye, Yori Gidron, Marc D. Gellman, M. Bryant Howren, Manjunath Harlapur, Daichi Shimbo, Keisuke Ohta, Naoya Yahagi, Elizabeth Franzmann, Abanish Singh, Linda C. Baumann, Alyssa Karel, Debra Johnson, Benjamin L. Clarke, Debra Johnson, Rachel Millstein, Karen Niven, Karen Niven, Eleanor Miles, J. Rick Turner, Barbara Resnick, Yori Gidron, Carter A. Lennon, Kelly S. DeMartini, Kristin L. MacGregor, Susan E. Collins, Megan Kirouac, J. Rick Turner, Abanish Singh, Yori Gidron, Yoshiharu Yamamoto, Urs M. Nater, Nicole Nisly, Debra Johnson, Derek Johnston, Ydwine Zanstra, Derek Johnston, Youngmee Kim, Della Matheson, Brooke McInroy, Christopher France, Shin Fukudo, Emiko Tsuchiya, Yoko Katayori, Martin Deschner, Norman B. Anderson, Chad Barrett, Mark A. Lumley, Lindsay Oberleitner, Stephan Bongard, Siqin Ye, Amy Jo Marcano-Reik, Seth Hurley, Seth Hurley, Anna Maria Patino-Fernandez, Anna C. Phillips, Tatsuo Akechi, Anna C. Phillips, Amy Jo Marcano-Reik, Nicole Brandt, Rachel Flurie, Sarah Aldred, Kim Lavoie, Manjunath Harlapur, Daichi Shimbo, Kate L. Jansen, Katherine T. Fortenberry, Molly S. Clark, Rachel Millstein, Toru Okuyama, William Whang, Mustafa Al’Absi, Bingshuo Li, Yori Gidron, J. Rick Turner, Elizabeth R. Pulgaron, Diana Wile, Linda C. Baumann, Alyssa Karel, Beth Schroeder, Mary C. Davis, Alex Zautra, Shannon L. Stark, William Whang, Ana Victoria Soto, Yori Gidron, Anthony J. Wheeler, Scott DeBerard, Josh Allen, Akihisa Mitani, Akihisa Mitani, Elizabeth R. Pulgaron, Akihisa Mitani, Jennifer Carter, William Whang, Beth Schroeder, Angela M. Hicks, Carolyn Korbel, Austin S. Baldwin, Kevin S. Spink, Darren Nickel, Michael Richter, Rex A. Wright, Julian F. Thayer, Michael Richter, Rex A. Wright, Deborah J. Wiebe +132 moreopenaire +3 more sources
