Results 181 to 190 of about 1,201,269 (362)

Impact of gastrectomy on efficacy and safety of second‐line chemotherapy patients with advanced gastric cancer: Exploratory analysis of two randomized phase III trials

Annals of Gastroenterological Surgery, EarlyView.
In an analysis of two RCTs of IRI‐based second‐line chemotherapy for AGC, patients with prior gastrectomy had better OS and PFS than patients without prior gastrectomy. Furthermore, patients with prior gastrectomy had a better prognosis in OS and PFS adjusted for background factors as well. Abstract Aims Second‐line chemotherapy (SLC) improves survival
Kazuhiro Nishikawa, Wasaburo Koizumi, Akira Tsuburaya, Motoko Suzuki, Satoshi Morita, Kazumasa Fujitani, Yusuke Akamaru, Ken Shimada, Hisashi Hosaka, Ken Nishimura, Takaki Yoshikawa, Toshimasa Tsujinaka, Junichi Sakamoto   +12 more
wiley   +1 more source

A mathematical perspective on the paradox that chemotherapy sometimes works backwards [PDF]

arXiv
Doctors are well aware that sometimes cancer treatments not only fail, but even work backwards, i.e. they make the treated tumor grow. In this work we present a mathematical perspective on this paradox in the case of chemotherapy, by studying a minimally parameterized mathematical model for the system composed of the tumor and the surrounding ...
arxiv  

Prognostic value of surgical treatment in elderly patients with ulcerative colitis‐associated colorectal cancer: A subanalysis of a nationwide Japanese multicenter study

Annals of Gastroenterological Surgery, EarlyView.
Our study examined the characteristics of elderly patients diagnosed with ulcerative colitis‐associated colorectal cancer. We showed that factors associated with aggressive tumor characteristics played a significant role in recurrence risk in the nonelderly patients, but not in the elderly patients.
Kinuko Nagayoshi, Yusuke Mizuuchi, Masafumi Nakamura, Koji Okabayashi, Motoi Uchino, Hiroki Ikeuchi, Tatsuki Noguchi, Soichiro Ishihara, Yoichi Ajioka, Kenichi Sugihara, from the Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers by the Japanese Society for Cancer of the Colon and Rectum   +10 more
wiley   +1 more source

Blood Lymphocyte Population 4 to 6 Years after Adjuvant Cyclic Chemotherapy for Operable Breast Carcinoma [PDF]

, 1985
Henric Blomgren, S Rotstein, B Petrini, J. Wasserman   +3 more
openalex   +1 more source

Three timepoint perioperative CEA levels are a prognostic factor for recurrence after adjuvant chemotherapy in patients with Stage II and III colorectal cancer

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate the relationship between the three timepoint perioperative CEA (ttpCEA) calculated at three timepoints and recurrence during the perioperative period in Stage II and III colorectal cancer (CRC) patients. A total of 538 patients were included for the training data and 329 patients for validation data, and 5‐y time‐to ...
Shodai Mizuno, Kohei Shigeta, Ryosuke Hara, Kyoko Sakamoto, Jumpei Nakadai, Hideo Baba, Hiroto Kikuchi, Yoko Adachi, Takehiro Shimada, Hirofumi Suzumura, Kiyoaki Sugiura, Shimpei Matsui, Ryo Seishima, Koji Okabayashi, Yuko Kitagawa   +14 more
wiley   +1 more source

Chemotherapy as an Adjuvant to Surgery for Colorectal Cancer

, 1975
Walter Lawrence, Jose J. Terz, SHELTON HORSLEY, Milton H. Donaldson, William L. Lovett, Peter Brown, B. W. Ruffner, William Regelson   +7 more
openalex   +2 more sources

Prospective, randomized study of adjuvant radiation and chemotherapy of operable carcinoma of the breast [PDF]

, 1986
K. Reusch, K.-D. Schulz, R. Bradley Sack, A. Bolte, R. Kaiser   +4 more
openalex   +1 more source

Preoperative sarcopenia negatively impacts short‐ and long‐term outcomes of rectal cancer: A propensity score‐matched analysis

Annals of Gastroenterological Surgery, EarlyView.
This study examined the effects of skeletal muscle mass on the short‐ and long‐term outcomes of rectal cancer. This study revealed that preoperative sarcopenia was associated with more total postoperative complications, more anastomotic leakage, and worse survival in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Kensuke Kaneko, Yuichiro Yokoyama, Hiroyuki Matsuzaki, Yuzo Nagai, Soichiro Ishihara   +9 more
wiley   +1 more source

Lipid metabolism in pancreatic cancer: emerging roles and potential targets

Cancer Communications, Volume 42, Issue 12, Page 1234-1256, December 2022., 2022
Abstract Pancreatic cancer is one of the most serious health issues in developed and developing countries, with a 5‐year overall survival rate currently <9%. Patients typically present with advanced disease due to vague symptoms or lack of screening for early cancer detection.
Xinpeng Yin, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Yuan Chen, Chengcheng Wang, Qiang Xu   +6 more
wiley   +1 more source

Comparison of post-operative radiotherapy and adjuvant chemotherapy in operable breast cancer patients

, 1979
Krystyna Kiel, Annie Chu, Robert W. Carey   +2 more
openalex   +1 more source