Results 191 to 200 of about 747,551 (253)

KRAS and BRAF mutations modify adjuvant chemotherapy outcomes in early stage colorectal cancer. [PDF]

NPJ Precis Oncol
Wankhede D, Rodriguez MJU, Edelmann D, Kloor M, Bläker H, Brobeil A, Roth W, Brenner H, Hoffmeister M.   +8 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Adjuvant Chemotherapy and Survival After Pelvic Exenteration for Gynecologic Cancers in the COREPEX Study.

JAMA Netw Open
Bizzarri N, Novák Z, Ricotta G, Cãpîlna ME, Giannarelli D, Domingo S, Chiantera V, Akilli H, Cibula D, Zach D, Miranda A, Korompelis P, Chacon E, Zapardiel I, Lampe B, Svintsitskyi V, Matylevich O, van Ramshorst GH, Taskiran C, Demirkiran F, Lengyel T, Vizzielli G, Loverro M, Fanfani F, Marchetti C, Ferron G, Martinez A, Gauroy E, Ladanyi E, Kiss LS, Lago V, Montesinos-Albert M, Di Donna MC, Cucinella G, Slama J, Rosta V, Muallem MZ, Kucukmetin A, Fagotti A, Salehi S, Querleu D.   +40 more
europepmc   +1 more source

Prognostic Scoring System for Pulmonary Metastasectomy in Colorectal Cancer: External Validation and Clinical Implications for Adjuvant Chemotherapy. [PDF]

Cancers (Basel)
Takahashi H, Yamauchi Y, Nishida T, Yanagiya M, Hashimoto H, Mun M, Azuma Y, Iwata T, Endo M, Iida T, Matsuguma H, Oyama T, Ohtsuka T, Sakao Y.   +13 more
europepmc   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Longitudinal Changes in Nutritional, Inflammatory, and CT-Derived Body Composition Markers During Adjuvant Chemotherapy for Stage II/III Colorectal Cancer. [PDF]

Cancers (Basel)
Hasegawa M, Momma T, Kimura S, Ichinose H, Yago H, Sato T, Ito M, Matsumoto T, Ujiie D, Chida S, Okayama H, Saito M, Sakamoto W, Kono K.   +13 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Dose-dense adjuvant chemotherapy in HER2-low breast cancer: An exploratory analysis of the GIM2 trial. [PDF]

Breast
Molinelli C, Delucchi V, Blondeaux E, Boni L, Poggio F, Soldato D, Antonj L, Arpino G, Nisticò C, Fabi A, De Laurentiis M, Buono G, Puglisi F, Nader-Marta G, Fozza A, Pitto F, Boncore F, Cardinali B, Fregatti P, Lambertini M, Del Mastro L.   +20 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Enhanced survival in resectable duodenal adenocarcinoma with adjuvant chemotherapy: evidence from a retrospective study. [PDF]

Front Oncol
Liu J, Fang Y, Wu G, Liu N, Bi D, Xie Y, Zhong Y, Zhang J, Zhao D, Sun Y.   +9 more
europepmc   +1 more source