Results 241 to 250 of about 392,253 (296)

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Tumor-Infiltrating Immune Cells Are More Abundant in Lung Metastases From Colorectal Cancer Than in Paired Primary Tumors and Their Prognostic Value Depends on Adjuvant Chemotherapy. [PDF]

Cancer Med
Kuznyecov D, Siesing C, Vidarsdottir H, Eberhard J, Brunnström H, Leandersson K, Jirström K.   +6 more
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

The effect of neo-adjuvant chemotherapy with 5-fluorouracil on the integrity of colonic anastomoses: a systematic review and meta-analysis of experimental studies on rats. [PDF]

Front Surg
Chernyshenko T, Polkin R, Ashyrov M, Shepelev V, Goncharuk R.   +4 more
europepmc   +1 more source

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

Selective Benefit of Adjuvant Chemotherapy in Stage II dMMR Colon Cancer with High-Risk Features or Poorly Differentiated Histology: A Retrospective Study. [PDF]

Cancers (Basel)
Huang Y, Gao Y, Li Y, Xie X, Pei J, Yao Y, Zhan T, Chen N, Leng J, Wang L, Zhao J, Wu A.   +11 more
europepmc   +1 more source

Initiation and Completion of Adjuvant Chemotherapy After Total Versus Partial Pancreaticoduodenectomy for Pancreatic Cancer. [PDF]

Ann Surg Oncol
Weber R, Kuehni FLM, Aeschbacher P, Perrodin SF, Andreou A, Kaibel H, Rohrmeier NM, Berger MD, Gloor B, Wenning AS.   +9 more
europepmc   +1 more source

Symptom cluster in patients with resected pancreatic cancer during adjuvant chemotherapy: A cross-sectional study. [PDF]

Asia Pac J Oncol Nurs
Wang Y, Xia N, Song Y, Shi N, Pan KC.
europepmc   +1 more source

Complications following upfront pancreatectomy with venous resection do not compromise adjuvant chemotherapy delivery and survival in pancreatic cancer. [PDF]

Langenbecks Arch Surg
Perri G, Grandi S, Liu M, Pellegrini R, Lin J, Canitano N, Guastella R, Lu Z, Bassi D, Cillo U, Jiang K, Marchegiani G.   +11 more
europepmc   +1 more source

Efficacy and safety of 3-month versus 6-month oxaliplatin-based adjuvant chemotherapy in colorectal cancer: a systematic review and meta-analysis. [PDF]

Front Oncol
Wu H, Li J, Miao J, Li J.
europepmc   +1 more source