Results 31 to 40 of about 1,425,061 (397)

Adjuvant Chemotherapy Guided by a 21‐Gene Expression Assay in Breast Cancer

New England Journal of Medicine, 2018
BACKGROUND The recurrence score based on the 21‐gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy
J. Sparano, R. Gray, D. Makower, K. Pritchard, K. Albain, D. Hayes, C. Geyer, E. Dees, M. Goetz, J. Olson, T. Lively, S. Badve, T. Saphner, L. Wagner, T. Whelan, M. Ellis, S. Paik, W. Wood, P. Ravdin, M. Keane, H. G. Gomez Moreno, P. Reddy, T. Goggins, I. Mayer, A. Brufsky, D. Toppmeyer, V. Kaklamani, J. Berenberg, J. Abrams, G. Sledge   +29 more
semanticscholar   +1 more source

An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer

Nature Communications, 2020
Immunosuppressive molecules are extremely valuable prognostic biomarkers across different cancer types. However, the diversity of different immunosuppressive molecules makes it very difficult to accurately predict clinical outcomes based only on a single
Jia-Bin Wang, Ping Li, Xiao-Long Liu, Q. Zheng, Yu-bin Ma, Yajun Zhao, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, L. Cao, Mi Lin, Li-chao Liu, Ning-Zi Lian, Ying-Hong Yang, Chang-ming Huang, C. Zheng   +16 more
semanticscholar   +1 more source

Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer [PDF]

, 2015
Neoadjuvant chemotherapy plus trastuzumab (NCT) increases the rate of pathological complete response (pCR) and event-free survival (EFS) compared to neoadjuvant chemotherapy (NC) alone in women with HER2 positive breast cancer (BC).
Ades, F, Ahmed, R, Asher, R, Beresford, M, De Azambuja, E, Gojis, O, Howell, SJ, Januszewski, A, Lewanski, C, Lythgoe, D, Macpherson, IRJ, Owadally, W, Palmieri, C, Riddle, P, Shah, D, Stanley, B, Yan, K   +16 more
core   +2 more sources

The course of cancer related fatigue up to ten years in early breast cancer patients. What impact in clinical practice? [PDF]

, 2017
Little is known about the cancer related fatigue (CRF) along cancer course and risk factors that could predict CRF development and persistence in breast cancer (BC) survivors.
Cognetti, F., Fabi, A., Falcicchio, C., Giannarelli, D., Maggi, G., Pugliese, P.   +5 more
core   +1 more source

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis. [PDF]

, 2017
PurposeThe risk of scalp metastases in patients using scalp cooling for preservation of hair during chemotherapy has been a concern but is poorly described.MethodsA systematic review and meta-analysis of longitudinal studies was undertaken to evaluate ...
Melin, Susan A, Rugo, Hope S, Voigt, Jeff   +2 more
core   +1 more source

Prognostic value of lymph node ratio and extramural vascular invasion on survival for patients undergoing curative colon cancer resection [PDF]

, 2015
There was no study funding. We are grateful to Tony Rafferty (Tailored Information for the People of Scotland, TIPs) for providing survival data.Peer reviewedPublisher ...
A Bhangu, A de Gramont, A O’Shea, A Sternberg, AC Berger, C MacKay, C N Parnaby, ED Courtney, F Cianchi, G I Murray, G Ramsay, GT Williams, H Ueno, HK Choi, J Betge, J Lykke, J Wang, L Bui, L Samuel, L Schiffmann, LH Sobin, M A Loudon, M Morris, N W Scott, NN Baxter, OH Sjo, P Quirke, R Rosenberg, R Rosenberg, SJ Moug, SL Chen, W Hohenberger   +31 more
core   +2 more sources

Prospective analysis of different combined regimens of stereotactic body radiation therapy and chemotherapy for locally advanced pancreatic cancer

Cancer Medicine, 2018
To identify impacts of different combined regimens of stereotactic body radiation therapy (SBRT) and chemotherapy on survival of patients with locally advanced pancreatic cancer (LAPC) and factors correlated with determinations of different combinations.
Xiaofei Zhu, Dongchen Shi, Fuqi Li, Xiaoping Ju, Yangsen Cao, Yuxin Shen, Fei Cao, Shuiwang Qing, Fang Fang, Zhen Jia, Huojun Zhang   +10 more
doaj   +1 more source

Proliferation Marker Ki67 as a Stratification Index of Adjuvant Chemotherapy for Resectable Mucosal Melanoma

Frontiers in Oncology, 2022
BackgroundAdjuvant chemotherapy has been shown to produce a favorable prognosis for patients with resectable mucosal melanoma (MM), resulting in the need for stratification to optimally select patients to benefit from adjuvant therapy.
Lirui Tang, Xiaoting Wei, Caili Li, Jie Dai, Xue Bai, Lili Mao, Zhihong Chi, Chuanliang Cui, Bin Lian, Bixia Tang, Yu Du, Xuan Wang, Yumei Lai, Xinan Sheng, Xieqiao Yan, Siming Li, Li Zhou, Yan Kong, Zhongwu Li, Lu Si, Jun Guo, Jun Guo   +21 more
doaj   +1 more source

The impact of loco-regional recurrences on metastatic progression in early-stage breast cancer: a multistate model [PDF]

, 2009
To study whether the effects of prognostic factors associated with the occurrence of distant metastases (DM) at primary diagnosis change after the incidence of loco-regional recurrences (LRR) among women treated for invasive stage I or II breast cancer ...
A Fourquet, AC Voogd, B Fisher, B Fisher, B Fisher, C Vrieling, C. J. van de Velde, D Cowen, E Touboul, Early Breast Cancer Trialists’ Collaborative Group, G Coulombe, G. H. de Bock, H Bartelink, H Kemperman, H Putter, H. Bartelink, H. Putter, HM Nielsen, I Soerjomataram, J Dongen Van, J Engel, J Hage Van der, J Hage Van der, J Ragaz, J. A. van der Hage, J. Bonnema, JA Dongen Van, JA Dongen Van, JG Nes Van, L Livi, M Clarke, M Leest Van der, M Sangen Van der, MA Bollet, N Kroman, P Broet, PC Clahsen, PH Elkhuizen, PH Elkhuizen, R Arriagada, R Arriagada, RS Punglia, U Veronesi, WS Halsted   +43 more
core   +4 more sources

Adjuvant concurrent chemoradiation therapy (CCRT) alone versus CCRT followed by adjuvant chemotherapy: Which is better in patients with radically resected extrahepatic biliary tract cancer?: a non-randomized, single center study

BMC Cancer, 2009
Background There is currently no standard adjuvant therapy for patients with curatively resected extrahepatic biliary tract cancer (EHBTC). The aim of this study was to analyze the clinical features and outcomes between patients undergoing adjuvant ...
Kim Tae-You, Im Seock-Ah, Jang Jin-Young, Chie Eui, Oh Do-Youn, Lim Kyu-Hyoung, Kim Sun-Whe, Ha Sung, Bang Yung-Jue   +8 more
doaj   +1 more source