Results 31 to 40 of about 1,201,269 (362)

Proliferation Marker Ki67 as a Stratification Index of Adjuvant Chemotherapy for Resectable Mucosal Melanoma

Frontiers in Oncology, 2022
BackgroundAdjuvant chemotherapy has been shown to produce a favorable prognosis for patients with resectable mucosal melanoma (MM), resulting in the need for stratification to optimally select patients to benefit from adjuvant therapy.
Lirui Tang, Xiaoting Wei, Caili Li, Jie Dai, Xue Bai, Lili Mao, Zhihong Chi, Chuanliang Cui, Bin Lian, Bixia Tang, Yu Du, Xuan Wang, Yumei Lai, Xinan Sheng, Xieqiao Yan, Siming Li, Li Zhou, Yan Kong, Zhongwu Li, Lu Si, Jun Guo, Jun Guo   +21 more
doaj   +1 more source

The efficacy of adjuvant chemotherapy for older adults with stage II/III gastric cancer: a retrospective cohort study

BMC Cancer, 2023
Background Adjuvant chemotherapy is recommended as the standard treatment for patients with stage II/III resected gastric cancer. However, it is unclear whether older patients also benefit from an adjuvant chemotherapy strategy.
Yu-Hsuan Shih, Hsin-Chen Lin, Po-Wei Liao, Cheng-Wei Chou, Cheng-Hsien Lin, Chiann-Yi Hsu, Chieh-Lin Jerry Teng, Feng-Hsu Wu, Shao-Ciao Luo, Shao-Hsuan Kao   +9 more
doaj   +1 more source

Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy

New England Journal of Medicine, 2017
BACKGROUND Patients who have residual invasive carcinoma after the receipt of neoadjuvant chemotherapy for human epidermal growth factor receptor 2 (HER2)‐negative breast cancer have poor prognoses.
N. Masuda, Soo-Jung Lee, S. Ohtani, Y. Im, Eun-Sook Lee, I. Yokota, K. Kuroi, S. Im, Byeong-Woo Park, Sung-Bae Kim, Y. Yanagita, S. Ohno, S. Takao, K. Aogi, H. Iwata, Joon Jeong, Aeree Kim, K. Park, H. Sasano, Y. Ohashi, M. Toi   +20 more
semanticscholar   +1 more source

Adjuvant Chemotherapy of Breast Cancer [PDF]

Breast Care, 2009
rence.’ The NCCN Practice Guidelines in Oncology Breast Cancer leave it open, intermediate and high-risk node negative patients are assigned to category 1: chemotherapy regimens comprising taxane and non-taxane containing regimens. Thus, guidelines currently do not provide real help.
Nitz, Ulrike, Cardoso, Fatima, Gnant, Michael, Thomssen, Christoph   +3 more
openaire   +3 more sources

Duration of Adjuvant Chemotherapy for Stage III Colon Cancer

New England Journal of Medicine, 2018
BACKGROUND Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer.
A. Grothey, A. Sobrero, A. Shields, T. Yoshino, J. Paul, J. Taieb, J. Souglakos, Q. Shi, R. Kerr, R. Labianca, J. Meyerhardt, D. Vernerey, T. Yamanaka, I. Boukovinas, J. Meyers, L. Renfro, D. Niedzwiecki, Toshiaki Watanabe, V. Torri, M. Saunders, D. Sargent, T. André, T. Iveson   +22 more
semanticscholar   +1 more source

Prospective analysis of different combined regimens of stereotactic body radiation therapy and chemotherapy for locally advanced pancreatic cancer

Cancer Medicine, 2018
To identify impacts of different combined regimens of stereotactic body radiation therapy (SBRT) and chemotherapy on survival of patients with locally advanced pancreatic cancer (LAPC) and factors correlated with determinations of different combinations.
Xiaofei Zhu, Dongchen Shi, Fuqi Li, Xiaoping Ju, Yangsen Cao, Yuxin Shen, Fei Cao, Shuiwang Qing, Fang Fang, Zhen Jia, Huojun Zhang   +10 more
doaj   +1 more source

Adjuvant concurrent chemoradiation therapy (CCRT) alone versus CCRT followed by adjuvant chemotherapy: Which is better in patients with radically resected extrahepatic biliary tract cancer?: a non-randomized, single center study

BMC Cancer, 2009
Background There is currently no standard adjuvant therapy for patients with curatively resected extrahepatic biliary tract cancer (EHBTC). The aim of this study was to analyze the clinical features and outcomes between patients undergoing adjuvant ...
Kim Tae-You, Im Seock-Ah, Jang Jin-Young, Chie Eui, Oh Do-Youn, Lim Kyu-Hyoung, Kim Sun-Whe, Ha Sung, Bang Yung-Jue   +8 more
doaj   +1 more source

A Retrospective Analysis using Deep-Learning Models for Prediction of Survival Outcome and Benefit of Adjuvant Chemotherapy in Stage II/III Colorectal Cancer [PDF]

arXiv, 2021
Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately predict survival benefit from postoperative chemotherapy.
arxiv  

Adjuvant chemotherapy in the elderly

Annals of Oncology, 2003
Cancer is predominantly a disease of the elderly: approximately 60% of all tumors and two-thirds of cancer-related deaths occur in those over 65 years of age. This proportion will grow with the expected increase in the size of the older population in the coming decades.
Biganzoli, Laura, Aapro, Matti
openaire   +3 more sources

Improving trial generalizability using observational studies [PDF]

, 2020
Complementary features of randomized controlled trials (RCTs) and observational studies (OSs) can be used jointly to estimate the average treatment effect of a target population. We propose a calibration weighting estimator that enforces the covariate balance between the RCT and OS, therefore improving the trial-based estimator's generalizability ...
arxiv   +1 more source