Results 51 to 60 of about 747,551 (253)

Prognostic nutritional index is an independent risk factor for continuing S-1 adjuvant chemotherapy in patients with pancreatic cancer who received neoadjuvant chemotherapy and surgical resection

BMC Cancer
Purpose Reports on the association of perioperative nutritional and inflammatory status with the clinical course of adjuvant chemotherapy did not include neoadjuvant chemotherapy.
Shinnosuke Kawahara, Toru Aoyama, Masaaki Murakawa, Rei Kanemoto, Daishi Takahashi, Yuto Kamioka, Itaru Hashimoto, Yukio Maezawa, Satoshi Kobayashi, Makoto Ueno, Naoto Yamamoto, Takashi Oshima, Norio Yukawa, Yasushi Rino, Aya Saito, Soichiro Morinaga   +15 more
doaj   +1 more source

Long-term effectiveness of adjuvant Goserelin in premenopausal women with early breast cancer [PDF]

, 2009
BACKGROUND: Systematic reviews have found that luteinizing hormone-releasing hormone (LHRH) agonists are effective in treating premenopausal women with early breast cancer.
Fornander, T, S. Forsyth, Johansson, Ulla,, T. Fornander, U. Johansson, Reczko, Krystyna,, B. Nordenskjold, Nordenskjold, Bo, Fornander, Tommy,, K. Reczko, Reczko, Krystyna, Fohlin, H, Hackshaw, Allan, Fornander, Tommy, Fohlin, Helena,, Valentini, Miriam,, H. Fohlin, Sainsbury, R, Fohlin, Helena, Johansson, U, Monson, Kathryn,, Reczko, K, M. Valentini, Forsyth, Sharon, Sainsbury, Richard,, Nicolucci, A, Monson, K, R. Sainsbury, Baum, M, Sainsbury, Richard, Valentini, Miriam, A. Hackshaw, Nordenskjöld, Bo,, Forsyth, Sharon,, M. Baum, A. Nicolucci, Nordenskjold, B, Fornander, T,, K. Monson, Johansson, Ulla, Nicolucci, Antonio,, Baum, Michael,, Baum, Michael, Hackshaw, Allan,, Hackshaw, A, Valentini, M, Monson, Kathryn, Nicolucci, Antonio, Forsyth, S   +48 more
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Early recurrence of pancreatic cancer after resection and during adjuvant chemotherapy

The Saudi Journal of Gastroenterology, 2012
Background/Aim: Adjuvant chemotherapy for 6 months is the current standard of care after potentially curative resection of pancreatic cancer and yields an overall survival of 15-20 months. Early tumor recurrence before or during adjuvant chemotherapy has
Richard Fischer, Matthias Breidert, Tobias Keck, Frank Makowiec, Christian Lohrmann, Jan Harder   +5 more
doaj   +1 more source

Adjuvant chemotherapy, not radiotherapy, prolongs survival for node-negative non–small cell lung cancer with positive surgical marginsCentral MessagePerspective

JTCVS Open, 2023
Objective: The study objective was to determine differences in survival depending on adjuvant therapy type, timing, and sequence in node-negative disease with positive margins after non–small cell lung cancer resection.
Arman Ashrafi, BA, Jeremy Yu, MS, Alexander T. Kim, BA, Jason C. Ye, MD, Elizabeth A. David, MD, Sean C. Wightman, MD, Scott M. Atay, MD, Takashi Harano, MD, Anthony W. Kim, MD, MS   +8 more
doaj   +1 more source

Adjuvant Chemotherapy in Elderly Patients with Early-stage Non-small Cell Lung Cancer

, 2019
Objective:Early-stage non-small cell lung cancer (NSCLC) constitutes approximately 25-30% of newly diagnosed lung cancers. Elderly patients with NSCLC have generallly been underrepresented in clinical studies. We explored adjuvant chemotherapy results in
Isik, Deniz, Acikgoz, Ozgur, UYGUN, KAZIM, Kazım UYGUN, Kaymaz, Samet, Deniz IŞIK, Ulaş IŞIK, ÖZDEN, ERCAN, Devrim ÇABUK, Özgür AÇIKGÖZ, Aydin, Dincer, Umut KEFELİ, IŞIK, ULAŞ, Ercan ÖZDEN, Sonkaya, Alper, Samet KAYMAZ, Dinçer AYDIN, Alper SONKAYA, KEFELİ, UMUT, ÇABUK, DEVRİM   +19 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Predictive value of a reduction in the level of high-density lipoprotein-cholesterol in patients with non-small-cell lung cancer undergoing radical resection and adjuvant chemotherapy: a retrospective observational study

Lipids in Health and Disease, 2021
Background Cancer patients often exhibit chemotherapy-associated changes in serum lipid profiles, however, their prognostic value before and after adjuvant chemotherapy on survival among non-small-cell lung cancer (NSCLC) patients is unknown.
Fan Luo, Kang-mei Zeng, Jia-xin Cao, Ting Zhou, Su-xia Lin, Wen-juan Ma, Yun-peng Yang, Zhong-han Zhang, Fei-teng Lu, Yan Huang, Hong-yun Zhao, Li Zhang   +11 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source