Results 71 to 80 of about 747,551 (253)

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Multicentre study of perioperative versus adjuvant chemotherapy for resectable colorectal liver metastases

BJS Open, 2019
Background It is not known whether perioperative chemotherapy, compared with adjuvant chemotherapy alone, improves disease‐free survival (DFS) in patients with upfront resectable colorectal liver metastases (CLM).
M.‐A. Allard, Y. Nishioka, N. Beghdadi, K. Imai, M. Gelli, S. Yamashita, Y. Kitano, T. Kokudo, Y.‐I. Yamashita, A. Sa Cunha, E. Vibert, D. Elias, D. Cherqui, D. Goere, R. Adam, H. Baba, K. Hasegawa   +16 more
doaj   +1 more source

Adjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0–1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER database

BMC Cancer, 2020
Background The benefit of adjuvant chemotherapy in invasive lobular carcinoma (ILC) is still unclear. The objective of the current study was to elucidate the effectiveness of adjuvant chemotherapy in hormone receptor (HR)-positive, human epidermal growth
Guangfu Hu, Guangxia Hu, Chengjiao Zhang, Xiaoyan Lin, Ming Shan, Yanmin Yu, Yongwei Lu, Ruijie Niu, Hui Ye, Cheng Wang, Cheng Xu   +10 more
doaj   +1 more source

Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer [PDF]

, 2007
Background Selective cyclooxygenase inhibitors may retard the progression of cancer, but they have enhanced thrombotic potential. We report on cardiovascular adverse events in patients receiving rofecoxib to reduce rates of recurrence of colorectal ...
Christopher C. McConkey, Justine L. Smith, McConkey, Christopher C., Midgley, RS, Kerr, DJ, Janet A. Dunn, Stokes, JC, Midgley, Rachel, Claire Iveson, McConkey, CC, HASH(0x55a67f94f158), Midgley, Rachel S. J., HASH(0x55a67f45c688), Iveson, Claire, David J. Kerr, Ravi Duvvuri, Iveson, C, Patrick Julier, Julier, P, Smith, JL, Joanne C. Stokes, Langman, Michael J., Julier, Patrick, Duvvuri, Ravi, Rachel S.J. Midgley, Smith, Justine L., Michael J. Langman, Dunn, Janet A., Duvvuri, R, Kerr, David J., Kerr, David, Langman, MJ, Stokes, Joanne C., Andrew Stanley, Stanley, A, Dunn, JA, Stanley, Andrew   +36 more
core   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

The Pathophysiological effects of adjuvant preoperative chemotherapy and/or radiotherapy on patients with advanced rectal cancer [PDF]

, 2013
Introduction The modern treatment of colorectal cancer consists of surgery, with or without adjuvant pre-operative radiotherapy, chemotherapy or chemoradiotherapy (APT) for selected cases. In the United Kingdom, therapy may be given prior to surgery in
Rahmani, Samir
core   +4 more sources

Efficacy variations of adjuvant chemotherapy across disease stages in duodenal adenocarcinoma: a multivariate survival analysis based on the SEER database [PDF]

Waike lilun yu shijian
Objective To investigate the efficacy of adjuvant chemotherapy for patients with duodenal adenocarcinoma (DAC) at different stages. Methods A retrospective analysis was performed on patients diagnosed with DAC between January 2000 and December 2021 using
WANG Yu, HU Kaixin, ZHAO Fengqing, LI Huangbao
doaj   +1 more source

Efficacy of Adjuvant Chemotherapy and Prognostic Factors for Patients with Extrahepatic Bile Duct Cancer

, 2017
BACKGROUND: Surgical resection is the only curative treatment for extrahepatic bile duct cancer. Additionally, the recurrence rate after curative surgery is relatively high, requiring adjuvant therapy.
박승우, 박정엽, 방승민, 이희승, 정재복, 송시영, 정문재, 이상훈   +7 more
core   +1 more source

Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]

, 2000
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source