Results 51 to 60 of about 1,201,269 (362)

The impact of Oncotype DX testing on adjuvant chemotherapy decision making in 1–3 node positive breast cancer

Cancer Reports, 2022
Background Oncotype DX testing has reduced the use of adjuvant chemotherapy in node‐negative early breast cancer but less is known about its impact in node positive patients.
Yogeshkumar Malam, Mohamed Rabie, Konstantinos Geropantas, Susanna Alexander, Simon Pain, Mina Youssef   +5 more
doaj   +1 more source

A regression framework for a probabilistic measure of cost-effectiveness [PDF]

arXiv, 2021
To make informed health policy decisions regarding a treatment, we must consider both its cost and its clinical effectiveness. In past work, we introduced the net benefit separation (NBS) as a novel measure of cost-effectiveness. The NBS is a probabilistic measure that characterizes the extent to which a treated patient will be more likely to ...
arxiv  

Tumor-associated Macrophages as Prognostic and Predictive Biomarkers for Postoperative Adjuvant Chemotherapy in Patients with Stage II Colon Cancer

Clinical Cancer Research, 2019
Purpose: For stage II colon cancer, the efficacy of postoperative adjuvant chemotherapy remains controversial. It is well known that tumor-associated macrophages (TAMs) are important in tumor progression.
Q. Feng, W. Chang, Y. Mao, G. He, P. Zheng, W. Tang, Ye Wei, L. Ren, Dexiang Zhu, M. Ji, Yongjiu Tu, X. Qin, Jianming Xu   +12 more
semanticscholar   +1 more source

Efficacy and Long-term Peripheral Sensory Neuropathy of 3 vs 6 Months of Oxaliplatin-Based Adjuvant Chemotherapy for Colon Cancer

JAMA Oncology, 2019
Key Points Question Can a shortened course of adjuvant oxaliplatin-based chemotherapy reduce peripheral sensory neuropathy (PSN) without compromising efficacy in patients with stage III colon cancer?
T. Yoshino, T. Yamanaka, E. Oki, M. Kotaka, D. Manaka, T. Eto, J. Hasegawa, A. Takagane, Masato Nakamura, Takeshi Kato, Y. Munemoto, S. Takeuchi, H. Bando, H. Taniguchi, M. Gamoh, M. Shiozawa, T. Mizushima, S. Saji, Y. Maehara, A. Ohtsu, M. Mori   +20 more
semanticscholar   +1 more source

The benefits and harms of adjuvant chemotherapy for non-small cell lung cancer in patients with major comorbidities: A simulation study.

PLoS ONE, 2022
BackgroundRandomized controlled trials (RCTs) have demonstrated a survival benefit for adjuvant platinum-based chemotherapy after resection of locoregional non-small cell lung cancer (NSCLC).
Amanda Leiter, Chung Yin Kong, Michael K Gould, Minal S Kale, Rajwanth R Veluswamy, Cardinale B Smith, Grace Mhango, Brian Z Huang, Juan P Wisnivesky, Keith Sigel   +9 more
doaj   +1 more source

Mathematical modeling of glioma invasion and therapy approaches via kinetic theory of active particles [PDF]

arXiv, 2022
A multiscale model for glioma spread in brain tissue under the influence of vascularization and vascular endothelial growth factors is proposed. It accounts for the interplay between the different components of the neoplasm and the healthy tissue and it investigates and compares various therapy approaches.
arxiv  

Making sense of adjuvant chemotherapy in colorectal cancer.

Journal of Gastrointestinal Oncology, 2019
Surgical resection is the only curative treatment for locoregional colon cancer. The goal of adjuvant chemotherapy is to eradicate micro-metastatic disease and improve survival. This has been most clearly demonstrated in stage III (node-positive) disease,
Gloria Chan, C. Chee
semanticscholar   +1 more source

Neo-adjuvant and adjuvant chemotherapy in bladder cancer

Annals of Oncology, 2007
Transitional cell carcinoma of the bladder represents the second most common genitourinary malignancy [1]; the clinical approach to muscle-invasive disease has been modified in the last decade, considering the important role of multidisciplinary team, including surgeon, oncologist and radiotherapist.
D'AURIA, GIULIANA, CIPROTTI, MARIKA, CONTE, DAVIDE, IACOVELLI, ROBERTO, PALAZZO, ANTONELLA, PELLEGRINO, ARIANNA, CORTESI, Enrico   +6 more
openaire   +3 more sources

Predictive value of a reduction in the level of high-density lipoprotein-cholesterol in patients with non-small-cell lung cancer undergoing radical resection and adjuvant chemotherapy: a retrospective observational study

Lipids in Health and Disease, 2021
Background Cancer patients often exhibit chemotherapy-associated changes in serum lipid profiles, however, their prognostic value before and after adjuvant chemotherapy on survival among non-small-cell lung cancer (NSCLC) patients is unknown.
Fan Luo, Kang-mei Zeng, Jia-xin Cao, Ting Zhou, Su-xia Lin, Wen-juan Ma, Yun-peng Yang, Zhong-han Zhang, Fei-teng Lu, Yan Huang, Hong-yun Zhao, Li Zhang   +11 more
doaj   +1 more source

Impact of adjuvant chemotherapy for radically resected esophageal squamous cell carcinoma: a propensity score matching analysis

Frontiers in Surgery, 2023
BackgroundThe aim of this study was to evaluate the impact of adjuvant chemotherapy in patients with radically resected esophageal squamous cell carcinoma (ESCC).MethodsPatients with esophageal cancer who underwent esophagectomy at our hospital from 2010
Shao-bin Chen, Di-tian Liu, Yu-ping Chen
doaj   +1 more source