Results 61 to 70 of about 765,314 (335)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Adjuvant radiotherapy improves progression-free survival in intracranial atypical meningioma
Radiation Oncology, 2019 Meningiomas are the most common primary tumors of the central nervous system. In patients with WHO grade I meningiomas no adjuvant therapy is recommended after resection.
Samaneh Hemmati +9 more
semanticscholar +1 more source
Salvage versus adjuvant radiotherapy after radical prostatectomy: argument for adjuvant radiotherapy [PDF]
Canadian Urological Association Journal, 2013 openaire +2 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Prognostic analysis of stage Ⅰ lung cancer based on SEER data
Zhongguo linchuang yanjiuObjective To explore the clinical characteristics and treatment methods that affect the prognosis of stage Ⅰlung cancer. Methods Clinical data of stage Ⅰ lung cancer patients diagnosed and treated with radical surgical resection from 2019 to 2021 were ...
LI Xiaowu，YUAN Yuan，HAN Liang
doaj +1 more source
Journal of Neurosurgery, 2018 In BriefIn this article, Chen et al. investigate the impact of adjuvant radiotherapy in 182 patients undergoing primary resection of atypical meningioma.
William C. Chen +11 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023 Objective·To evaluate the survival effects of neoadjuvant radiation therapy and adjuvant radiotherapy on the patients with rectal cancer treated with chemotherapy and surgery by using the Surveillance, Epidemiology and End Results (SEER) database of the ...
WANG Anjun, LIU Ningning
doaj +1 more source
The results of adjuvant radiotherapy in endometrial carcinoma
Gynecological Endocrinology, 2009 To examine the clinical characteristics and treatment outcomes in patients with endometrial cancer receiving adjuvant radiotherapy.A total of 157 patients who received postoperative radiotherapy (RT) between 1999 and 2008 were evaluated, retrospectively. The mean age was 59 years (34-82). All patients received RT following surgery.
Aylin Fidan Korcum +2 more
openaire +3 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source