Results 131 to 140 of about 574 (182)

What are the limits of adjuvanticity?

Vaccine, 2001
Vaccines developed traditionally following empirical approaches have often limited problems of immunogenicity, probably due to the low level of purity of the active component(s) they contain. The application of new technologies to vaccine development is leading to the production of purer (e.g. recombinant) antigens which, however, tend to have a poorer
G, Del Giudice, A, Podda, R, Rappuoli
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Adjuvante dermatokosmetische Aknetherapie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2010
Adjuvant dermato-cosmetic therapy in acne is an essential part of the concept of treating acne after initiation and during maintenance therapy. Those are mechanical peeling, chemical peeling and its combination. It needs supervision by an experienced dermatologist.
Christiane Bayerl, Klaus Degitz, Eva Meigel, Martina Kerscher   +3 more
openaire   +1 more source

The adjuvanticity of interleukin 1 in vivo.

The Journal of Immunology, 1983
Abstract Interleukin 1 (IL 1) was shown to enhance in vivo secondary antibody responses of mice to a protein antigen. The activity was found to be dose and time dependent. The maximum enhancing effect was obtained with 2000 LAF units of IL 1 given 2 hr after the priming dose of antigen.
M J, Staruch, D D, Wood
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How is Adjuvanticity Recognised?

1983
The activities of the immune system are customarily divided into specific functions mediated by immunoglobulin, and a range of other functions which are loosely classed by “non-specific”. Many of these latter do however exhibit a degree of specificity.
R. B. Taylor, C. A. Morrison
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Triggering Intracellular Receptors for Vaccine Adjuvantation

Trends in Immunology, 2016
Immune adjuvants are components that stimulate, potentiate, or modulate the immune response to an antigen. They are key elements of vaccines in both the prophylactic and therapeutic domains. In the past decade substantial progress in our understanding of innate immunity has paved the way for the design of next-generation adjuvants that stimulate a wide
Alice Gutjahr, Gérard Tiraby, Eric Perouzel, Bernard Verrier, Stéphane Paul   +4 more
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Adjuvante systemische Therapie

2006
Eine grosere Anzahl von einzelnen Studien, insbesondere aber die Metaanalyse der „Early Breast Cancer Trialist’s Collaborative Group“ (EB-CTCG), haben den Nutzen einer Chemo- und Hormontherapie in der adjuvanten Behandlung des Mammakarzinomes eindrucksvoll bewiesen.
Volker Möbus, Nicolai Maass, Corinna Crohns, Christoph Mundhenke, Walter Jonat   +4 more
openaire   +1 more source

Surface hydrophobicity of microparticles modulates adjuvanticity

Journal of Materials Chemistry B, 2013
Polymeric microparticles are promising adjuvants and they exhibit various physicochemical characteristics that can regulate the immune response, including hydrodynamic size, morphology, and surface properties, among others. Surface hydrophobicity is also a key microparticle characteristic, but how it affects microparticle adjuvanticity remains unknown.
Yuan, Liu, Ying, Yin, Lianyan, Wang, Weifeng, Zhang, Xiaoming, Chen, Xiaoxiao, Yang, Junjie, Xu, Guanghui, Ma   +7 more
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Mechanisms of vaccine adjuvanticity at mucosal surfaces

Animal Health Research Reviews, 2000
AbstractThe vast majority of pathogens invade via mucosal surfaces, including those of the intestine. Vaccination directly on these surfaces may induce local protective immunity and prevent infection and disease. Although vaccine delivery to the gut mucosa is fraught with obstacles, immunization can be enhanced using adjuvants with properties specific ...
D L, Foss, M P, Murtaugh
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Factors Influencing the Allergenicity and Adjuvanticity of Allergens

Immunotherapy, 2011
IgE-mediated allergic disorders affect up to 25% of the population in industrialized countries and result in a Th2-polarized immune response to innocuous environmental proteins, so-called allergens. Among a large number of proteins to which humans are exposed to, only a minute fraction are allergens.
Stephan, Deifl, Barbara, Bohle
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Mucosal adjuvanticity of immunostimulatory DNA sequences

Springer Seminars in Immunopathology, 2000
Unlike the skin which is relatively impermeable, mucosal surfaces allow for the intake of oxygen, water, and other nutrients, and the excretion of metabolic byproducts. This relatively permeable nature places unique constraints and requirements on the immunocytes which protect mucosal surfaces, and makes these sites particularly susceptible to ...
A A, Horner, N, Cinman, A, Ronaghy, E, Raz   +3 more
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