Results 191 to 200 of about 34,009 (241)

Sitravatinib enhances doxorubicin cytotoxicity in doxorubicin‐resistant K562/ADM cells

Bulletin of the Korean Chemical Society, Volume 47, Issue 3, Page 355-360, March 2026.
A repositioning‐based screening identified sitravatinib that synergistically enhances doxorubicin efficacy in doxorubicin‐resistant leukemia cells. Abstract Drug resistance remains a major obstacle in leukemia treatment, and combination therapy has emerged as an effective strategy to overcome this limitation. This study aimed to identify compounds with
Min Jeong Ahn, Min Gyo Seo, Eun Hye Kim, Seong Hwan Kim   +3 more
wiley   +1 more source

Experimental study on tissue-engineered urethral graft for repairing urethral defects in a rabbit model. [PDF]

Front Bioeng Biotechnol
Jiang A, Tian Y, Sun C, Lian Y, Zhai H.
europepmc   +1 more source

Is Navigated Transcranial Magnetic Stimulation Capable of Detecting Different Motor Cell Clusters Within the Precentral Gyrus Using a Single Pulse Protocol?

Brain and Behavior, Volume 16, Issue 3, March 2026.
ABSTRACT Objective In 2021, Rossi et al. developed a cortical mapping algorithm that enabled a reliable mapping of an anatomical subdivision of the precentral gyrus. This approach allowed for the differentiation between an anterior subregion, characterized by lower excitability and slower motor responses, and a posterior subregion (named “M1 proper ...
Gregor Durner, Georg Colbus, Vera Marschal, Giulia Sestito, Hans‐Georg Kesseler, Lennart Sannwald, Nadja Grübel, Christian Rainer Wirtz, Andrej Pala, Ralf Becker   +9 more
wiley   +1 more source

P300 enhances glycolysis and dox resistance in DLBCL by upregulating HK2 expression through histone lactylation. [PDF]

BMC Cancer
Song X, Fu H, Zhong X, Yu N, Zhang W.
europepmc   +1 more source

Depression Risk in Type 1 Versus Type 2 Diabetes: Cross‐Sectional Analysis of Body Mass Index (BMI) in a Nationally Diverse Cohort

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
In a national All of Us cohort, major depressive disorder was more common in type 1 diabetes and non‐diabetic participants than type 2 diabetes. BMI was independently associated with depression and modestly suppressed non‐diabetic versus type 2 diabetes differences. ABSTRACT Introduction Major depressive disorder (MDD) commonly co‐occurs with diabetes,
Natalia Cruz‐Vespa, Michael L. Thomas, Michael J. McCarthy, Alejandro D. Meruelo   +3 more
wiley   +1 more source

Immunological and molecular insights into acinar-ductal metaplasia and atypical flat lesions as precursor lesions of pancreatic ductal adenocarcinoma. [PDF]

J Exp Clin Cancer Res
Yavas A, Boshoven L, Horny K, Haensch S, Goering W, Schlensog M, Haeberle L, Esposito I.   +7 more
europepmc   +1 more source

Microbial Contributions to Primate Reproduction

Evolutionary Anthropology: Issues, News, and Reviews, Volume 35, Issue 1, March 2026.
ABSTRACT Reproduction is a complex process, and microbes play a far greater role than previously imagined. This review explores the ways that microbiomes influence the rich tapestry of reproductive processes and outcomes within the primate lineage, including pre‐copulatory and post‐copulatory mechanisms.
Silvia Carboni, Abigail E. Asangba, Amanda D. Melin   +2 more
wiley   +1 more source

An immunomodulatory hydrogel featuring antibacterial and ROS-scavenging functions for enhanced burn wound healing. [PDF]

J Nanobiotechnology
Zhao XS, Zhang LP, Wang G, Yang QY, Cheng XJ, Wu CY, Wu D, Dong CB, Yang YT, Wang YF, Cai XJ, Zhu NW.   +11 more
europepmc   +1 more source

CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity

Glia, Volume 74, Issue 3, March 2026.
CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert, Joana Paes de Faria, Olaf Jahn, Ege Bilgin, Nikola Łukasik, Chethana Rao, Mišo Mitkovski, Fritz Benseler, Nils Brose, Sophie B. Siems, Sandra Goebbels, Wiebke Möbius, Helge Ewers, João B. Relvas, Hauke B. Werner   +14 more
wiley   +1 more source

Multi-Marker Approach in Sepsis: A Clinical Role Beyond SOFA Score. [PDF]

Medicina (Kaunas)
Lee GH, Kim H, Moon HW, Yun YM, Lee S, Hur M.   +5 more
europepmc   +1 more source