Impact of Whole Plant Extract of Pergularia daemia on Glycoproteins in Dimethylbenz(A)Anthracene Induced Hamster Buccal Pouch Carcinogenesis [PDF]
Background: Oral squamous cell carcinoma is a major component of a diverse group of neoplasms often referred to as ‘head and neck cancer’. Frequent smoking and/or alcohol consumption are two major risk factors for oral cancer.
Vaithiyanathan Veluchamy+1 more
doaj +1 more source
Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to
Viviana De Caro+3 more
doaj +1 more source
DNA methylation at the DAT promoter and risk for psychopathology. Intergenerational transmission between school-age youths and their parents in a community sample [PDF]
Background: The effect of gene polymorphisms and promoter methylation, associated with maladaptive developmental outcomes, vary depending on environmental factors (e.g., parental psychopathology).
Claudio D’Addario+9 more
core +2 more sources
Acute convulsions in children are a common emergency worldwide. Benzodiazepines are the recommended first line treatment. Intravenous lorazepam is inexpensive, long acting and the first line drug in resource-rich settings. However, comparable efficacy by
Samantha Lissauer+7 more
doaj +1 more source
Formulation and evaluation of a mucoadhesive buccal tablet of mefenamic acid
Buccal route of administration has many advantages such as improving patient compliance, bypassing the GIT and hepatic first pass effect. The objectives are to formulate mucoadhesive buccal tablet using Mefenamic acid and compatible excipients, and to ...
Karen Lu Li, Agnes Llamasares Castillo
doaj +1 more source
A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery
Administration of drugs via the buccal route has attracted much attention in recent years. However, developing systems with satisfactory adhesion under wet conditions and adequate drug bioavailability still remains a challenge.
Shanshan Hu+9 more
doaj +1 more source
MUCOADHESIVE POLYMERIC FILMS OF ACYCLOVIR PRONIOSOMES FOR BUCCAL ADMINISTRATION
Objective: The aim of the present work was to formulate and evaluate proniosomes of the poorly soluble drug, acyclovir incorporated in mucoadhesive polymeric films for improved buccal mucosal permeability of the drug while achieving prolonged release. Methods: Acyclovir was formulated as proniosomes using Span 60 and cholesterol.
DEEKSHA U. SUVARNA+3 more
openaire +2 more sources
Background: to assess the intuitiveness of parents’ administration of pediatric emergency devices (inhalation, rectal, buccal, nasal, and auto-injector).
Ruth Melinda Müller+5 more
doaj +1 more source
Objectives: To investigate the success rate of supplemental intraseptal and buccal infiltration anaesthesia in mandibular molars undergoing endodontic therapy/extraction when the inferior alveolar nerve block has failed.
Giath Gazal+5 more
doaj +1 more source
Use of buccal morphine in the management of pain in children with life-limiting conditions: Results of a laboratory study [PDF]
BACKGROUND: Children and infants with impaired swallow or compromised enteral absorption require alternative routes for administration of analgesia. Recent clinical guidance and practice for paediatric palliative care teams, who often treat such children,
Bluebond-Langner, M+4 more
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