Results 61 to 70 of about 1,860,717 (249)

Integrated microanatomy and microstructure of the maxillary tooth plate reveal a reinforced feeding system and tougher diet in Late Triassic Hyperodapedontinae (Rhynchosauria, Archosauromorpha)

The Anatomical Record, EarlyView.
Abstract Hyperodapedontine rhynchosaurs possessed a unique oral apparatus, long interpreted as an adaptation for processing abrasive and resistant plant material. However, the microanatomical and histological evidence supporting this interpretation remains poorly documented.
Caio A. Scartezini, Pedro L. B. Pruciano, Brodsky D. M. Farias, Marina B. Soares   +3 more
wiley   +1 more source

The lower deciduous dentition of protodidelphids (Mammalia, Marsupialia) from the Itaboraí Basin (lower Eocene), Brazil, and the validity of “Riolestes capricornicus” (Goin et al., 2009)

The Anatomical Record, EarlyView.
Abstract The Itaboraí Basin, Southeastern Brazil, preserved one of the most diverse mammalian faunas from the Paleogene, with Metatheria comprising more than 60% of its diversity. Among identified metatherian clades, it has been argued that Paucituberculata is represented by “Riolestes capricornicus”.
Leonardo M. Carneiro, Hugo Bampi, João P. P. Araújo, Marina B. Soares, Gustavo R. Oliveira   +4 more
wiley   +1 more source

Fabrication and Characterization of Amisulpride Nanofibers for Enhanced Oral Pharmacodynamic Properties [PDF]

Pharmaceutical Sciences
Background: Buccal route for drug administration has several advantages over oral route, such as improved systemic bioavailability via avoidance of first-pass metabolism and drug degradation in the gastro-intestinal tract.
Shimaa Mohamed Ashmawy, Maysa Abdallah Hussien, Sally El Sayed Abu-Risha, Gamal Mohamed El Maghraby, Amal Ali Elkordy, Ebtessam Ahmed Essa   +5 more
doaj   +1 more source

Development and Characterization of Inkjet Printed Edible Films for Buccal Delivery of B-Complex Vitamins

Pharmaceuticals, 2020
Buccal films containing two vitamins, i.e., thiamine hydrochloride (THCl) and nicotinic acid (NA), were fabricated via two-dimensional (2D) inkjet printing.
Georgios Eleftheriadis, Paraskevi Kyriaki Monou, Eleftherios Andriotis, Elisavet Mitsouli, Nikoleta Moutafidou, Catherine Markopoulou, Nikolaos Bouropoulos, Dimitrios Fatouros   +7 more
doaj   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari, Caroline S. Copeland, Georgia C. Richards   +2 more
wiley   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

Buccal administration of mucoadhesive blend films saturated with propranolol loaded nanoparticles

Asian Journal of Pharmaceutical Sciences, 2018
The aims of this study were to prepare and characterize hydroxypropyl methylcellulose (HPMC)/polycarbophil (PC) mucoadhesive blend films saturated with propranolol hydrochloride (PNL)-loaded nanoparticles to improve permeability of drugs that undergo ...
Pakorn Kraisit, Sontaya Limmatvapirat, Manee Luangtana-Anan, Pornsak Sriamornsak   +3 more
doaj   +1 more source

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

British Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry, Muhammad Umair Khan, Barbara Conway, Syed Shahzad Hasan   +3 more
wiley   +1 more source

Design, development, and optimization of mucoadhesive buccal films of ganaxolone for enhanced bioavailability

Journal of Applied Pharmaceutical Research
Background: CDD disorder affects children mainly during their first three months of life. The buccal route offers advantages over oral administration for ganaxolone by avoiding first-pass metabolism and providing direct systemic absorption.
Onkar Pawar, Rahul Godge, Ganesh Shinde, Kailas Barde, Akshay Vikhe   +4 more
doaj   +1 more source

Beyond wound sealing: A dual‐functional adhesive nanofiber membrane promoting coagulation and osteogenesis in extraction sites

BMEMat, EarlyView.
Inspired by the suction mechanics of octopus suckers, a dual‐layer nanofiber membrane integrates antibacterial protection, strong wet adhesion, and osteogenic support, offering a bioinspired strategy for effective hemostasis and alveolar bone preservation.
Huijing Ma, Liheng Gao, Hao Liang, Wentao Jiang, Junyi Wang, Jiajia Wang, Shuhan Duan, Lingxi Meng, Adilijiang Yimiti, Wenjie Zhang   +9 more
wiley   +1 more source