Results 21 to 30 of about 234,737 (309)

Cutaneous Adverse Events in Newly Approved FDA Non-cancer Drugs: A Systematic Review

Drugs in R&D, 2020
The prevalence of cutaneous adverse events attributable to newly approved anti-cancer drugs has been well reviewed in the dermatologic literature. In contrast, over 75% of US Food and Drug Administration approvals in the past 5 years have been for non ...
Paul C. Macklis, Brittany Dulmage, Brady Evans, Misha Rosenbach, Johann E. Gudjonsson, Benjamin H. Kaffenberger   +5 more
doaj   +1 more source

Clinical impact and a prognostic marker of early rituximab treatment after rituximab reimbursement in Korean pemphigus patients

Frontiers in Immunology, 2022
Pemphigus is an autoimmune mucocutaneous blistering disease caused by autoantibodies against desmogleins. Rituximab effectively treats pemphigus by inducing remission and rapidly reducing corticosteroid dosage.
Ahreum Song, Jieun Jang, Jieun Jang, Ayeong Lee, Seo Yeon Min, Sang Gyun Lee, Soo-Chan Kim, Jaeyong Shin, Jong Hoon Kim   +8 more
doaj   +1 more source

Ethosomes and organogels for cutaneous administration of crocin

Biomedical Microdevices, 2016
The present study describes the production and characterization of phosphatidylcholine based ethosomes and organogels, as percutaneous delivery systems for crocin. Crocin presence did not influence ethosome morphology, while the drug slightly increased ethosome mean diameter.
Esposito E, Drechsler M, Huang N, Pavoni G, Cortesi R, Santonocito D, PUGLIA, CARMELO   +6 more
openaire   +4 more sources

Cutaneous Pseudolymphoma Following Administration of Lornoxicam

Acta Dermato-Venereologica, 2007
Since aspirin was introduced over a century ago, many new anti-inflammatory agents have been marketed. NSAIDs are currently the most commonly prescribed agents in Western medicine (1). Their widespread use has resulted in a number of well-documented adverse reactions. These most frequently involve the gastro-intestinal tract, causing discomfort, nausea
Stavrianeas, N.G., Katoulis, A.C., Bozi, E., Toumbis-Ioannou, E., Kanelleas, A.I., Makris, M., Kalogeromitros, D., Panayiotides, I.   +7 more
openaire   +3 more sources

Toxic Epidermal Necrolysis after Pemetrexed and Cisplatin for Non-Small Cell Lung Cancer in a Patient with Sharp Syndrome [PDF]

, 2012
Background: Pemetrexed is an antifolate drug approved for maintenance and second-line therapy, and, in combination with cisplatin, for first-line treatment of advanced nonsquamous non-small cell lung cancer.
Aguiar D, Azukizawa H, Barlési F, Bastuji-Garin S, Belani CP, Bosch-Barrera J, Bracke A, Cohen MH, Cornelia Then, Daniel Müller, Del Pozzo-Magana BR, Fuld AD, Grader-Beck T, Harr T, Iung, Jobst C. von Einem, Kardaun SH, Lopes G, Martin Reincke, Michael J. Flaig, Mockenhaupt M, Rudolf M. Huber, Schneck J, Seiwert TY, Shih C, Tan SK, Tummino C, Vitiello M, Yun SJ   +28 more
core   +1 more source

Phase II evaluation of VDC-1101 in canine cutaneous T-cell lymphoma. [PDF]

, 2014
BackgroundCanine cutaneous T-cell lymphoma (CTCL) is an uncommon disease for which efficacious therapies are lacking. The novel anticancer nucleotide prodrug VDC-1101 (formerly known as GS-9219) has shown efficacy in dogs with multicentric lymphoma.
Burgess, KE, Burton, JH, Morges, MA, Saba, CF, Thamm, DH, Vail, DM   +5 more
core   +2 more sources

Excitation of cutaneous C nociceptors by intraplantar administration of anandamide [PDF]

Brain Research, 2009
Anandamide has been characterized as both an endocannabinoid and endovanilloid. Consistent with its actions as an endovanilloid, previous studies have demonstrated that anandamide can excite primary sensory neurons in vitro via transient receptor potential vanilloid type one (TRPV1) receptors.
Carl, Potenzieri, Thaddeus S, Brink, Donald A, Simone   +2 more
openaire   +2 more sources

Evaluation of Hydrogel Suppositories for Delivery of 5-Aminolevulinic Acid and Hematoporphyrin Monomethyl Ether to Rectal Tumors

Molecules, 2016
We evaluated the potential utility of hydrogels for delivery of the photosensitizing agents 5-aminolevulinic acid (ALA) and hematoporphyrin monomethyl ether (HMME) to rectal tumors.
Xuying Ye, Huijuan Yin, Yu Lu, Haixia Zhang, Han Wang   +4 more
doaj   +1 more source

Full length interleukin 33 aggravates radiation-induced skin reaction [PDF]

, 2017
The interleukin (IL)-1 family member IL-33 has been described as intracellular alarmin with broad roles in wound healing, skin inflammation but also autoimmunity.
Adam, Susanne, Frey, Benjamin, Frey, Silke, Gaipl, Udo S., Gilchrist, Derek, Hahn, Madelaine, Hueber, Axel J., Krönke, Gerhard, Kurow, Olga, McInnes, Iain B., Schett, Georg, Schmitt, Verena, Schuster, Louis, Wirtz, Stefan   +13 more
core   +3 more sources

Successful outcome of mucormycosis in two children on induction therapy for acute lymphoblastic leukemia

Indian Journal of Medical and Paediatric Oncology, 2013
Zygomycetes are one of the less common causes of invasive fungal infections in patients with the hematological malignancies. We report two cases of acute lymphoblastic leukemia in the pediatric age group, complicated by disseminated cutaneous ...
Anshul Gupta, Sandeep Jain, Charu Agrawal, Gauri Kapoor   +3 more
doaj   +1 more source