Results 31 to 40 of about 234,737 (309)

Acute Hepatic Porphyrias: Review and Recent Progress. [PDF]

, 2019
The acute hepatic porphyrias (AHPs) are a group of four inherited diseases of heme biosynthesis that present with episodic, acute neurovisceral symptoms.
Andant, Anderson, Andersson, Badawy, Balwani, Bissell, Bissell, Bloomer, Bonkovsky, Bonkovsky, Bonkovsky, Bonkovsky, Bonkowsky, Bonkowsky, Bonkowsky, Bylesjo, Chen, D’Avola, Ferrer, Glueck, Handschin, Jeans, Lambrecht, Lane, Marsden, McGuire, Pallet, Sardh, Sardh, Shen, Singal, Stein, Stewart, Tchernitchko, Wahlin, Watson, Watson, Willandt, Wu, Yarra, Yasuda   +40 more
core   +1 more source

Therapeutic advances in the topical treatment of cutaneous leishmaniasis: A review.

PLoS Neglected Tropical Diseases, 2021
Cutaneous leishmaniasis has been endemic since decades. Millions of cases are reported worldwide specially in developing and underdeveloped countries. There are 2 major types of cutaneous leishmaniasis based on the causating species found in different ...
Marium Azim, Saeed Ahmad Khan, Saleem Ullah, Shafiq Ullah, Syed Ishtiaq Anjum   +4 more
doaj   +1 more source

Polymeric Microneedles for Transdermal Delivery of Rivastigmine: Design and Application in Skin Mimetic Model

Pharmaceutics, 2022
In the last years, microneedles (MNs) have been considered a valuable, painless, and minimally invasive approach for controlled transdermal drug delivery (TDD).
Tânia M. T. Guimarães, Tânia Moniz, Cláudia Nunes, Maya Margaritova Zaharieva, Mila Kaleva, Krassimira Yoncheva, Hristo Najdenski, Sofia A. Costa Lima, Salette Reis   +8 more
doaj   +1 more source

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]

, 2019
Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S, Cappuzzo, F, Cartenì, G, Cognetti, F, Cortesi, E, De Giglio, A, De Giorgi, U, Giannarelli, D, Panni, S, Pazzola, A, Porta, C, Procopio, G, Raimondi, A, Rastelli, F, Rossetti, S, Sabbatini, R, Sobrero, A, Sternberg, Cn, Surico, G, Tassinari, D, Tortora, G, Turci, D, Verzoni, E   +22 more
core   +3 more sources

Factors that influence cutaneous reactions following administration of thiopentone and atracurium [PDF]

Anaesthesia, 1988
Summary Atracurium was administered by a variety of techniques to determine whether these influence the onset or duration of muscular relaxation, and the frequency of cutaneous reactions, after a standard induction dose of thiopentone.
A G, Lynas, R S, Clarke, J P, Fee, J E, Reid   +3 more
openaire   +2 more sources

CUTANEOUS ADMINISTRATION OF SALICYLATES IN RHEUMATISM, GOUT, ETC. [PDF]

JAMA: The Journal of the American Medical Association, 1898
Dr. Edmund L. Gross of Paris, in a recently published brochure, presents several new ideas. He says that though the various affections classed under gouty or rheumatic often differ widely as to their manifestations, they incontestably possess numerous traits in common.
openaire   +1 more source

Gellan Nanohydrogels: Novel Nanodelivery Systems for Cutaneous Administration of Piroxicam [PDF]

Molecular Pharmaceutics, 2018
The feasibility to use gellan nanohydrogels (Ge-NHs) as delivery system for the cutaneous administration of piroxicam (PRX) was investigated using gellan conjugated with cholesterol or riboflavin. The in vitro skin penetration studies through human epidermis were performed using a saturated aqueous drug solution, a 50% w/v Transcutol aqueous solution ...
Musazzi, Umberto M., Cencetti, Claudia, Franzé, Silvia, Zoratto, Nicole, Di Meo, Chiara, Procacci, Patrizia, Matricardi, Pietro, Cilurzo, Francesco   +7 more
openaire   +3 more sources

Cross-linked chitosan/lysozyme hydrogels with inherent antibacterial activity and tuneable drug release properties for cutaneous drug administration

Science and Technology of Advanced Materials, 2023
Gels with high drug release sustainability and intrinsic antibacterial properties are of high practical potential for cutaneous drug administration, particularly for wound care and skin disease treatment.
Wing-Fu Lai, Obireddy Sreekanth Reddy, Dahong Zhang, Haicui Wu, Wing-Tak Wong   +4 more
doaj   +1 more source

CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses [PDF]

, 2017
CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites and plays prominent roles in inflammatory pathologies and cancer. It has therefore been highlighted as an important therapeutic target.
A Mantovani, A Rot, A Rot, A Zlotnik, A Zlotnik, AA Filardy, AE Cardona, AEI Proudfoot, C Schinke, D Marvel, DI Gabrilovich, F Bachelerie, F Balkwill, F Porcheray, F Sallusto, FR Balkwill, G Cacalano, H Saiwai, HM Baldwin, J Dalli, J Schindelin, J Yang, J-I Youn, J-I Youn, K Kishida, KM Hertzer, L Liu, M-C Lo, MK Ho, O Soehnlein, P Ranganathan, P Scapini, RA Navarro-Xavier, RM Devalaraja, S Milatovic, T Jamieson, T Jamieson, T Kakinuma, TJ Schall   +38 more
core   +1 more source

Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]

, 2020
Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu, Constantin, Vlad Denis, Radaschin, Diana Sabina, Stana, Paunica, Tatu, Alin Laurentiu   +4 more
core   +2 more sources