Results 31 to 40 of about 2,878,283 (349)

Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus--report of 17 cases and review of the literature [PDF]

, 2013
Cutaneous manifestations occur frequently in systemic lupus erythematosus (SLE) and are pathognomonic in subacute-cutaneous lupus erythematosus (SCLE) and chronic cutaneous lupus erythematosus (CCLE).
Hofmann, SC, Isenberg, DA, Leandro, MJ, Morris, SD   +3 more
core   +1 more source

Toxic Epidermal Necrolysis after Pemetrexed and Cisplatin for Non-Small Cell Lung Cancer in a Patient with Sharp Syndrome [PDF]

, 2012
Background: Pemetrexed is an antifolate drug approved for maintenance and second-line therapy, and, in combination with cisplatin, for first-line treatment of advanced nonsquamous non-small cell lung cancer.
Aguiar D, Azukizawa H, Barlési F, Bastuji-Garin S, Belani CP, Bosch-Barrera J, Bracke A, Cohen MH, Cornelia Then, Daniel Müller, Del Pozzo-Magana BR, Fuld AD, Grader-Beck T, Harr T, Iung, Jobst C. von Einem, Kardaun SH, Lopes G, Martin Reincke, Michael J. Flaig, Mockenhaupt M, Rudolf M. Huber, Schneck J, Seiwert TY, Shih C, Tan SK, Tummino C, Vitiello M, Yun SJ   +28 more
core   +1 more source

The relationship between local scalp skin temperature and cutaneous perfusion during scalp cooling [PDF]

, 2007
Cooling the scalp during administration of chemotherapy can prevent hair loss. It reduces both skin blood flow and hair follicle temperature, thus affecting drug supply and drug effect in the hair follicle. The extent to which these mechanisms contribute
Janssen, Francis-Paul E.M., Leeuwen, Gerard M.J. van, Rajan, Vinayakrishnan, Steenbergen, Wiendelt, Steenhoven, Anton A. van   +4 more
core   +4 more sources

Serious Cutaneous Toxicities with Immune Checkpoint Inhibitors in the U.S. Food and Drug Administration Adverse Event Reporting System.

The Oncologist, 2019
Cutaneous toxicities frequently occurred with immune checkpoint inhibitors (ICIs), although clinical and pharmacological features are incompletely characterized. The U.S. Food and Drug Administration Adverse Event Reporting System was queried to describe
E. Raschi, I. Antonazzo, M. La Placa, A. Ardizzoni, E. Poluzzi, F. De Ponti   +5 more
semanticscholar   +1 more source

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]

, 2019
Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S, Cappuzzo, F, Cartenì, G, Cognetti, F, Cortesi, E, De Giglio, A, De Giorgi, U, Giannarelli, D, Panni, S, Pazzola, A, Porta, C, Procopio, G, Raimondi, A, Rastelli, F, Rossetti, S, Sabbatini, R, Sobrero, A, Sternberg, Cn, Surico, G, Tassinari, D, Tortora, G, Turci, D, Verzoni, E   +22 more
core   +3 more sources

Toward Understanding Drug Incorporation and Delivery from Biocompatible Metal–Organic Frameworks in View of Cutaneous Administration

ACS Omega, 2018
Although metal–organic frameworks (MOFs) have widely demonstrated their convenient performances as drug-delivery systems, there is still work to do to fully understand the drug incorporation/delivery processes from these materials.
S. Rojas, I. Colinet, D. Cunha, T. Hidalgo, F. Salles, C. Serre, N. Guillou, P. Horcajada   +7 more
semanticscholar   +1 more source

Management of trypanosomiasis and leishmaniasis [PDF]

, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford, Alvar, Alvar, Barrett, Barrett, Ben Salah, Berman, Bern, Brun, Brun, Burri, Chappuis, Coura, Croft, Croft, El-Sayed, Frearson, Hailu, Jacobs, Jacobs, Le Loup, Lessa, M. P. Barrett, Miranda-Verastegui, Paine, Pinazo, Priotto, Rassi, Reithinger, Rodgers, S. L. Croft, Stuart, Sundar, Sundar, Sundar, Sundar, Torreele, Vanhollebeke, Vincent, Voogd   +39 more
core   +2 more sources

Combined Systemic and Intratumoral Administration of Human Papillomavirus Vaccine to Treat Multiple Cutaneous Basaloid Squamous Cell Carcinomas

JAMA dermatology, 2018
Importance Squamous cell carcinoma (SCC) is the second most common form of skin cancer, and its incidence is increasing. When surgical management is not an option, finding a safe and efficacious treatment is a challenge.
A. Nichols, Adrianna M. Gonzalez, E. Clark, W. Khan, A. Rosen, Wellington Guzman, H. Rabinovitz, E. Badiavas, R. Kirsner, T. Ioannides   +9 more
semanticscholar   +1 more source

Evaluation of Hydrogel Suppositories for Delivery of 5-Aminolevulinic Acid and Hematoporphyrin Monomethyl Ether to Rectal Tumors

Molecules, 2016
We evaluated the potential utility of hydrogels for delivery of the photosensitizing agents 5-aminolevulinic acid (ALA) and hematoporphyrin monomethyl ether (HMME) to rectal tumors.
Xuying Ye, Huijuan Yin, Yu Lu, Haixia Zhang, Han Wang   +4 more
doaj   +1 more source

Phase II evaluation of VDC-1101 in canine cutaneous T-cell lymphoma. [PDF]

, 2014
BackgroundCanine cutaneous T-cell lymphoma (CTCL) is an uncommon disease for which efficacious therapies are lacking. The novel anticancer nucleotide prodrug VDC-1101 (formerly known as GS-9219) has shown efficacy in dogs with multicentric lymphoma.
Burgess, KE, Burton, JH, Morges, MA, Saba, CF, Thamm, DH, Vail, DM   +5 more
core   +2 more sources