Results 71 to 80 of about 2,820,921 (304)

Lactobacillus Reuteri Vesicles Regulate Mitochondrial Function of Macrophages to Promote Mucosal and Cutaneous Wound Healing

Advancement of science
The interplay between bacteria and their host influences the homeostasis of the human immune microenvironment, and this reciprocal interaction also affects the process of tissue damage repair.
Yuan Chen, Xiaoyao Huang, Anqi Liu, S. Fan, Shiyu Liu, Zihan Li, Xiaoxue Yang, Hao Guo, Meiling Wu, Meng Liu, Peisheng Liu, Fei Fu, Siying Liu, K. Xuan   +13 more
semanticscholar   +1 more source

Severe cutaneous and neurologic toxicity in melanoma patients during vemurafenib administration following anti-PD-1 therapy

Cancer immunology research, 2013
Severe systemic toxicities developed in two patients during vemurafenib therapy following disease progression after treatment with anti-PD-1 agents; these results have important implications for the management of melanoma patients and future clinical ...
Douglas B. Johnson, Erika K Wallender, Daniel N Cohen, Sunaina S. Likhari, J. Zwerner, J. Powers, Lisa Shinn, M. Kelley, R. Joseph, J. Sosman   +9 more
semanticscholar   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Psychosocial stress enhances IgE-mediated triphasic cutaneous reaction in mice: Antagonism by Yokukan-san (a Kampo medicine) and diazepam

Allergology International, 2001
Background: In the present study, we investigated the effect of social isolation stress on IgE-mediated triphasic cutaneous reactions after 2,4-dinitrofluorobenzene (DNFB) challenge in male BALB/c mice passively sensitized with anti-dinitrophenol (DNP ...
Eiichi Tahara, Wenjuan Wu, Taku Satoh, Tomohiro Yamada, lzumi Kurosaki, Hiroichi Nagai, Shinyu Nunome, Katsutoshi Terasawa, Ikuo Saiki   +8 more
doaj   +1 more source

Skin manifestations associated with checkpoint inhibitors

JEADV Clinical Practice, 2022
Immune checkpoint inhibitors (ICIs) are a relatively novel class of drugs whose administration has been approved for several malignancies. Adverse events are quite common, and the skin is the most frequently involved organ.
Gianluca Nazzaro, Stefano Buffon, Serena Giacalone, Carlo Alberto Maronese, Angelo Valerio Marzano   +4 more
doaj   +1 more source

Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration

Burns & Trauma, 2019
AbstactCutaneous regeneration at the wound site involves several intricate and dynamic processes which require a series of coordinated interactions implicating various cell types, growth factors, extracellular matrix (ECM), nerves, and blood vessels ...
Peng Hu, Qinxin Yang, Qi Wang, C. Shi, Dali Wang, U. Armato, I. D. Prà, A. Chiarini   +7 more
semanticscholar   +1 more source

Induction of passive cutaneous anaphylaxis by oral administration of antigen.

Journal of Nippon Medical School, 1997
Passive cutaneous anaphylaxis (PCA) reaction was developed by Ovary et al. as an animal model of mainly human type I allergic inflammation reaction. This is the most sensitive reaction for the detection of cutaneously sensitizing antibodies and provides a very effective means by which to investigate immunological reactions concerning the mechanisms of ...
Kawasumi, Kou, Mizutani, Yuko, Yokomuro, Kozo, Takeuchi, Yoshio   +3 more
openaire   +3 more sources

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Penile microvascular endothelial function in hypertensive patients: effects of acute type 5 phosphodiesterase inhibition

Brazilian Journal of Medical and Biological Research, 2018
The primary aim of this study was to evaluate penile endothelial microvascular function in patients with primary arterial hypertension and age-matched normotensive subjects using laser speckle contrast imaging (LSCI).
V. Verri, A.A. Brandão, E. Tibirica
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source