Results 211 to 220 of about 65,774 (303)

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

An LNP antiviral siRNA drug cocktail delivered intranasally is effective against a range of respiratory viruses. [PDF]

Virol J
Oti VB, Ahmed T, Gao W, Acharya D, Wales-Earl L, Hicks A, McMillan NA, Idris A.   +7 more
europepmc   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Retrospective case series of two‐stage folded paramedian forehead flap nasal reconstruction without cartilage grafts

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Full‐thickness nasal defects of the tip, soft triangle, and ala are commonly reconstructed using a paramedian forehead flap with cartilage grafts or an epithesis. However, these approaches may be associated with donor‐site morbidity and psychological burden.
Conrad Hempel, Viktor Schnabel, Jan‐Christoph Simon, Sonja Grunewald   +3 more
wiley   +1 more source

Neffy: A latest needle-free epinephrine. [PDF]

Saudi J Anaesth
Chittoria K, Mukesh A, Sharma A.
europepmc   +1 more source

Hamman's crunch—A pathognomonic sign of pneumomediastinum

Equine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh, C. R. Daniel, J. A. Keen, N. J. Parkinson, B. C. McGorum   +4 more
wiley   +1 more source

Oxytocin attenuates fear learning via enhancing somatostatin interneuron-mediated local GABAergic inhibition in the prelimbic cortex. [PDF]

Sci Adv
Xu H, Li Y, Cui X, Zhang Y, Wu X, Zhuo SS, He M, Xiao L.   +7 more
europepmc   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Rapid reduction of suicidal ideation with transient dissociative and "drunken gait" symptoms after intranasal esketamine, with music intervention: a case report. [PDF]

Front Psychiatry
Tian H, Zhang Z, He Y, Su Y, Zhu X, Ding Y, Yu H, Jin L, Liu J.   +8 more
europepmc   +1 more source