Results 1 to 10 of about 157,530 (311)
Pharmaceutics, 2022 Efforts in discovering new and effective neurotherapeutics are made daily, although most fail to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous solubility, limited permeability through biological membranes ...
Sara Meirinho +4 more
doaj +1 more source
Clinical Evaluation over Intranasal Administration of Acepromazine and Diazepam in Pigeons (Columba livia domestica) [PDF]
Iranian Journal of Veterinary Surgery, 2023 Safe and effective sedation methods are as much momentous for small birds as for other animals not only for surgical procedures but also for safe handling and diagnostic and clinical procedures such as radiography, wound dressing, blood collection, and ...
Nasser Vajdi, Shohreh Alian Samakkhah
doaj +1 more source
Animals, 2021 The world is currently facing an ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease is a highly contagious respiratory disease which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Salleh Annas, Mohd Zamri-Saad
doaj +1 more source
Evaluation of Recent Intranasal Drug Delivery Systems to the Central Nervous System
Pharmaceutics, 2022 Neurological diseases continue to increase in prevalence worldwide. Combined with the lack of modifiable risk factors or strongly efficacious therapies, these disorders pose a significant and growing burden on healthcare systems and societies.
Tyler P. Crowe, Walter H. Hsu
doaj +1 more source
Translational Considerations in the Development of Intranasal Treatments for Epilepsy
Pharmaceutics, 2023 Epilepsy is a common and serious neurological disorder, to which a high proportion of patients continue to be considered “drug-resistant”, despite the availability of a host of anti-seizure drugs.
Richard N. Prentice, Shakila B. Rizwan
doaj +1 more source
Pharmaceutics, 2021 Diazepam is one of the most prescribed anxiolytic and anticonvulsant that is administered through intravenous (IV), oral, intramuscular, intranasal, and rectal routes.
Sundus Khalid +9 more
doaj +1 more source
Novel Targets and Interventions for Cognitive Complications of Diabetes
Frontiers in Physiology, 2022 Diabetes and cognitive dysfunction, ranging from mild cognitive impairment to dementia, often coexist in individuals over 65 years of age. Vascular contributions to cognitive impairment/dementia (VCID) are the second leading cause of dementias under the ...
Victoria Wolf +5 more
doaj +1 more source
Recent Advances in Intranasal Liposomes for Drug, Gene, and Vaccine Delivery
Pharmaceutics, 2023 Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles produced from cholesterol and phospholipids. Recently, liposomes have been widely administered intranasally for systemic and brain delivery. From the nasal cavity, liposome-
Van-An Duong +2 more
doaj +1 more source
Pharmaceutics, 2022 Intranasal administration is a promising route for brain drug delivery. However, it can be difficult to formulate drugs that have low water solubility into high strength intranasal solutions.
Patrícia C. Pires +3 more
doaj +1 more source
A comparative study of the effect of intranasal dexamethasone and normal saline on the occurrence of nausea and vomiting after hysterectomy: a clinical trial study [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023 Background. Many studies have been performed to prevent nausea and vomiting after surgery with different drugs alone or in combination, but no definite answer has been given yet.
Hamidreza Shetabi +2 more
doaj +1 more source