Results 21 to 30 of about 157,530 (311)

Comparison of intranasal midazolam versus intranasal ketamine for preoperative anesthetic sedation in pediatric patients

The Indian Anaesthetists' Forum, 2020
Introduction: During induction of anesthesia anxiety of children may be reduced more effectively by sedative medication than parental presence. Keeping in view, the necessity of reducing preoperative anxiety and postoperative psychological problem in ...
Nandini Chouhan, Janhavi Thatte, Deepak Phalgune, Charushila Patkar   +3 more
doaj   +1 more source

Corticosteroids for the common cold [PDF]

, 2015
BACKGROUND: The common cold is a frequent illness, which, although benign and self limiting, results in many consultations to primary care and considerable loss of school or work days. Current symptomatic treatments have limited benefit.
Del Mar, Chris B., Glasziou, Paul P., Hayward, Gail, Heneghan, Carl J., Perera, Rafael, Thompson, Matthew J.   +5 more
core   +1 more source

Intranasal esketamine as therapeutic option: a case report of an adolescent with treatment resistant depression

Frontiers in Psychiatry, 2023
Depression is among the most common mental health disorders worldwide and treatment resistant depression (TRD) represents a major challenge for both patients and clinicians.
Katrin Skala, Kamer Doganay, Harald Eder, Dunja Mairhofer, Katrin Neubacher, Paul L. Plener, Paul L. Plener   +6 more
doaj   +1 more source

A multicenter, open-label, long-term safety and tolerability study of DFN-02, an intranasal spray of sumatriptan 10 mg plus permeation enhancer DDM, for the acute treatment of episodic migraine. [PDF]

, 2017
BackgroundDFN-02 is a novel intranasal spray formulation composed of sumatriptan 10 mg and a permeation-enhancing excipient comprised of 0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside (DDM).
Allenby, Kent, Brand-Schieber, Elimor, Cady, Roger K, Munjal, Sagar, Rapoport, Alan M, Spierings, Egilius LH   +5 more
core   +1 more source

Case report: Intramuscular ketamine or intranasal esketamine as a treatment in four patients with major depressive disorder and comorbid anorexia nervosa

Frontiers in Psychiatry, 2023
IntroductionA comorbid diagnosis of a depressive disorder is a negative prognostic factor for individuals with AN, and novel treatments are needed to target depressive symptoms in this population. One emerging promising treatment for depressive disorders
Johanna Louise Keeler, Janet Treasure, Janet Treasure, Hubertus Himmerich, Hubertus Himmerich, Madeline Brendle, Madeline Brendle, Claire Moore, Reid Robison, Reid Robison   +9 more
doaj   +1 more source

Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment

Pharmaceuticals, 2022
A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic ...
Randa Mohammed Zaki, Mohammed F. Aldawsari, Manal A. Alossaimi, Shaikah F. Alzaid, Vidya Devanathadesikan Seshadri, Alanood S. Almurshedi, Basmah Nasser Aldosari, Rehab Mohammad Yusif, Ossama M. Sayed   +8 more
doaj   +1 more source

Nasal Drug Delivery Systems: An Overview [PDF]

, 2015
Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R., Ghori, Muhammad U., Mahdi, Mohammed H., Smith, Alan M.   +3 more
core   +1 more source

Ameliorating Impact of Prophylactic Intranasal Oxytocin on Signs of Fear in a Rat Model of Traumatic Stress

Frontiers in Behavioral Neuroscience, 2018
Oxytocin treatment reduces signs of long-term emotional stress after exposure to trauma; however, little is known about the potential protective effects of oxytocin treatment on behavioral and physiological changes associated with extreme stress exposure.
Micah D. Renicker, Nicholas Cysewski, Samuel Palmer, Dmytro Nakonechnyy, Andrew Keef, Morgan Thomas, Krisztian Magori, David P. Daberkow   +7 more
doaj   +1 more source

Intranasal Delivery: Effects on the Neuroimmune Axes and Treatment of Neuroinflammation

Pharmaceutics, 2020
This review highlights the pre-clinical and clinical work performed to use intranasal delivery of various compounds from growth factors to stem cells to reduce neuroimmune interactions.
Elizabeth M. Rhea, Aric F. Logsdon, William A. Banks, Michelle E. Erickson   +3 more
doaj   +1 more source

RETRACTED: QbD-based rivastigmine tartrate-loaded solid lipid nanoparticles for enhanced intranasal delivery to the brain for Alzheimer's therapeutics

Frontiers in Aging Neuroscience, 2022
Alzheimer's disease (AD) is a neurodegenerative disease that affects a wide range of populations and is the primary cause of death in various countries.
Deepshi Arora, Deepshi Arora, Shailendra Bhatt, Manish Kumar, Ravinder Verma, Yugam Taneja, Nikita Kaushal, Abhishek Tiwari, Varsha Tiwari, Athanasios Alexiou, Athanasios Alexiou, Sarah Albogami, Saqer S. Alotaibi, Vineet Mittal, Rajeev K. Singla, Rajeev K. Singla, Deepak Kaushik, Gaber El-Saber Batiha   +17 more
doaj   +1 more source