Results 21 to 30 of about 107,310 (319)

A comparative study of the effect of intranasal dexamethasone and normal saline on the occurrence of nausea and vomiting after hysterectomy: a clinical trial study [PDF]

مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023
Background. Many studies have been performed to prevent nausea and vomiting after surgery with different drugs alone or in combination, but no definite answer has been given yet.
Hamidreza Shetabi, Leili Adinehmehr, Zahra Salehi-Cheliche   +2 more
doaj   +1 more source

Intranasal dexmedetomidine and intranasal ketamine association allows shorter induction time for pediatric sedation compared to intranasal dexmedetomidine and oral midazolam [PDF]

, 2022
Background: Non-painful diagnostic procedures require an inactive state for a prolonged time, so that sedation is often needed in younger children to perform the procedures.
Trombetta, Andrea, Ronfani, Luca, Barbi, Egidio, Cossovel, Francesca, Ramondo, Augusto, Cozzi, Giorgio, Saccari, Alessia, Riccio, Guglielmo   +7 more
core   +1 more source

Lipid and Polymeric Nanoparticles: Successful Strategies for Nose-to-Brain Drug Delivery in the Treatment of Depression and Anxiety Disorders

Pharmaceutics, 2022
Intranasal administration has gained an increasing interest for brain drug delivery since it allows direct transport through neuronal pathways, which can be quite advantageous for central nervous system disorders, such as depression and anxiety ...
Margarida Alberto, Ana Cláudia Paiva-Santos, Francisco Veiga, Patrícia C. Pires   +3 more
doaj   +1 more source

Nano-Encapsulated Melatonin: A Promising Mucosal Adjuvant in Intranasal Immunization against Chronic Experimental T. gondii Infection

Tropical Medicine and Infectious Disease, 2022
Melatonin (MLT) is now emerging as one of the universally accepted immunostimulators with broad applications in medicine. It is a biological manipulator of the immune system, including mucosal ones. MLT was encapsulated in solid lipid nanoparticles (SLNs)
Doaa E. Said, Eglal I. Amer, Eman Sheta, Shaimaa Makled, Hala E. Diab, Fadwa M. Arafa   +5 more
doaj   +1 more source

Intranasal delivery of a chimpanzee adenovirus vector expressing a pre-fusion spike (BV-AdCoV-1) protects golden Syrian hamsters against SARS-CoV-2 infection

Frontiers in Cellular and Infection Microbiology, 2022
We evaluated the immunogenicity and protective ability of a chimpanzee replication-deficient adenovirus vectored COVID-19 vaccine (BV-AdCoV-1) expressing a stabilized pre-fusion SARS-CoV-2 spike glycoprotein in golden Syrian hamsters.
Shen Wang, Long Xu, Ting Mu, Mian Qin, Ping Zhao, Liang Xie, Linsen Du, Yue Wu, Nicolas Legrand, Karine Mouchain, Guillaume Fichet, Yi Liu, Yi Liu, Wenhao Yin, Jin Zhao, Min Ji, Bo Gong, Michel Klein, Michel Klein, Ke Wu, Ke Wu   +20 more
doaj   +1 more source

Comparison of intranasal midazolam versus intranasal ketamine for preoperative anesthetic sedation in pediatric patients

The Indian Anaesthetists' Forum, 2020
Introduction: During induction of anesthesia anxiety of children may be reduced more effectively by sedative medication than parental presence. Keeping in view, the necessity of reducing preoperative anxiety and postoperative psychological problem in ...
Nandini Chouhan, Janhavi Thatte, Deepak Phalgune, Charushila Patkar   +3 more
doaj   +1 more source

Intranasal esketamine as therapeutic option: a case report of an adolescent with treatment resistant depression

Frontiers in Psychiatry, 2023
Depression is among the most common mental health disorders worldwide and treatment resistant depression (TRD) represents a major challenge for both patients and clinicians.
Katrin Skala, Kamer Doganay, Harald Eder, Dunja Mairhofer, Katrin Neubacher, Paul L. Plener, Paul L. Plener   +6 more
doaj   +1 more source

Intranasal (IN) COVID-19 vaccines - a breakthrough

, 2023
Emerging variants of COVID-19 have threatened the effectiveness of intramuscular (IM) vaccines since that are made to target only the spike protein.
Ramandeep Singh Gambhir, Jyotsana Singh, Ridhi Matariya, Ridhima Sood, Balwinder Singh, Khushdeep Kaur   +5 more
core   +1 more source

Case report: Intramuscular ketamine or intranasal esketamine as a treatment in four patients with major depressive disorder and comorbid anorexia nervosa

Frontiers in Psychiatry, 2023
IntroductionA comorbid diagnosis of a depressive disorder is a negative prognostic factor for individuals with AN, and novel treatments are needed to target depressive symptoms in this population. One emerging promising treatment for depressive disorders
Johanna Louise Keeler, Janet Treasure, Janet Treasure, Hubertus Himmerich, Hubertus Himmerich, Madeline Brendle, Madeline Brendle, Claire Moore, Reid Robison, Reid Robison   +9 more
doaj   +1 more source

Brain Targeting of Quetiapine Fumarate via Intranasal Delivery of Loaded Lipospheres: Fabrication, In-Vitro Evaluation, Optimization, and In-Vivo Assessment

Pharmaceuticals, 2022
A liposphere system for intranasal delivery of quetiapine fumarate (QTF) was created to assess the potential for enhanced drug delivery. We investigated the effects of particle size, entrapment effectiveness, poly dispersibility index, and pluronic ...
Randa Mohammed Zaki, Mohammed F. Aldawsari, Manal A. Alossaimi, Shaikah F. Alzaid, Vidya Devanathadesikan Seshadri, Alanood S. Almurshedi, Basmah Nasser Aldosari, Rehab Mohammad Yusif, Ossama M. Sayed   +8 more
doaj   +1 more source