Results 31 to 40 of about 157,530 (311)
A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe +14 more
core +2 more sources
Formulating low-solubility or low-permeability drugs is a challenge, particularly with the low administration volumes required in intranasal drug delivery.
Patrícia C. Pires +9 more
doaj +1 more source
The purpose of the present work was to develop nanoemulsion-based formulations of mirtazapine for intranasal delivery using a spray actuator to target the brain for treating depression.
Mohammed Ghazwani +10 more
doaj +1 more source
Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]
Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R +3 more
core +2 more sources
Neurodegenerative diseases (NDDs), a global growing concern, are posing significant social and economic challenges, making the efficient delivery of medications to the brain a pressing demand.
Authman M. Alsamarrai +2 more
doaj +1 more source
A Comparative Study on Intranasal Versus Intravenous Lorazepam in the Management of Acute Seizure in Children [PDF]
Introduction: The acute seizure in childhood is a medical emergency which is usually managed by benzodiazepines used as a first line of therapy. There are no strict guidelines of using intranasal lorazepam in India.
Nandan Rudra +2 more
doaj +3 more sources
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome [PDF]
Background: Down syndrome (DS) individuals, by the age of 40s, are at increased risk to develop Alzheimer-like dementia, with deposition in brain of senile plaques and neurofibrillary tangles.
Arena, Andrea +9 more
core +3 more sources
Francisella tularensis, the causative agent of the fatal human disease known as tularemia is classified as a Category A Select Agent by the Centers for Disease Control.
Ahd A. Mansour +6 more
doaj +1 more source
Oxytocin treatment in pediatric populations
The role of endogenous oxytocin as neuromodulator of birth, lactation and social behaviors is well-recognized. Moreover, the use of oxytocin as a facilitator of social and other behaviors is becoming more and more accepted.
Adrienne Elise Taylor +3 more
doaj +1 more source
Cellular immune response of Staphylococcus aureus enterotoxin B in Balb/c mice through intranasal infection [PDF]
Background and Aim: Staphylococcus aureus produces various superantigen exotoxins, including staphylococcal enterotoxin B (SEB). It causes fatal anaphylactic reactions and toxic shock.
Hidayatun Nisa Purwanasari +5 more
doaj +1 more source

