Results 31 to 40 of about 157,530 (311)

A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus [PDF]

open access: yes, 2010
Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively.
Bernadet, Philippe   +14 more
core   +2 more sources

Innovative Aqueous Nanoemulsion Prepared by Phase Inversion Emulsification with Exceptional Homogeneity

open access: yesPharmaceutics, 2023
Formulating low-solubility or low-permeability drugs is a challenge, particularly with the low administration volumes required in intranasal drug delivery.
Patrícia C. Pires   +9 more
doaj   +1 more source

Formulation of Intranasal Mucoadhesive Thermotriggered In Situ Gel Containing Mirtazapine as an Antidepressant Drug

open access: yesGels, 2023
The purpose of the present work was to develop nanoemulsion-based formulations of mirtazapine for intranasal delivery using a spray actuator to target the brain for treating depression.
Mohammed Ghazwani   +10 more
doaj   +1 more source

Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]

open access: yes, 2020
Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R   +3 more
core   +2 more sources

An Elucidation of Contemporary Brain Targeting Tactics Employed in the Treatment of Neurodegenerative Diseases

open access: yesArchives of Pharmaceutical Sciences Ain Shams University, 2023
Neurodegenerative diseases (NDDs), a global growing concern, are posing significant social and economic challenges, making the efficient delivery of medications to the brain a pressing demand.
Authman M. Alsamarrai   +2 more
doaj   +1 more source

A Comparative Study on Intranasal Versus Intravenous Lorazepam in the Management of Acute Seizure in Children [PDF]

open access: yesFolia Medica, 2021
Introduction: The acute seizure in childhood is a medical emergency which is usually managed by benzodiazepines used as a first line of therapy. There are no strict guidelines of using intranasal lorazepam in India.
Nandan Rudra   +2 more
doaj   +3 more sources

Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome [PDF]

open access: yes, 2018
Background: Down syndrome (DS) individuals, by the age of 40s, are at increased risk to develop Alzheimer-like dementia, with deposition in brain of senile plaques and neurofibrillary tangles.
Arena, Andrea   +9 more
core   +3 more sources

An Improved Tobacco Mosaic Virus (TMV)-Conjugated Multiantigen Subunit Vaccine Against Respiratory Tularemia

open access: yesFrontiers in Microbiology, 2018
Francisella tularensis, the causative agent of the fatal human disease known as tularemia is classified as a Category A Select Agent by the Centers for Disease Control.
Ahd A. Mansour   +6 more
doaj   +1 more source

Oxytocin treatment in pediatric populations

open access: yesFrontiers in Behavioral Neuroscience, 2014
The role of endogenous oxytocin as neuromodulator of birth, lactation and social behaviors is well-recognized. Moreover, the use of oxytocin as a facilitator of social and other behaviors is becoming more and more accepted.
Adrienne Elise Taylor   +3 more
doaj   +1 more source

Cellular immune response of Staphylococcus aureus enterotoxin B in Balb/c mice through intranasal infection [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Staphylococcus aureus produces various superantigen exotoxins, including staphylococcal enterotoxin B (SEB). It causes fatal anaphylactic reactions and toxic shock.
Hidayatun Nisa Purwanasari   +5 more
doaj   +1 more source

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