Results 191 to 200 of about 65,774 (303)

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Intranasal administration of stem cells and their derivatives for neurological and respiratory disorders: a systematic review of human clinical trials. [PDF]

Front Aging Neurosci
Habiba UE, Sathyanarayanan R, Shamim S, Manian A, Haider A, Sarwar I, Greene DL.   +6 more
europepmc   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

Allergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang   +18 more
wiley   +1 more source

Effects of cellular receptors on the vaccine efficacies of adenovirus vector-based vaccines following intramuscular and intranasal administration. [PDF]

Sci Rep
Onishi R, Shiota A, Nakatani H, Tachibana M, Shimizu K, Hirai T, Yoshioka Y, Sakurai F, Mizuguchi H.   +8 more
europepmc   +1 more source

Modification of a breast pump suction pattern increases milk yield during the first 4 days postpartum

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Adding 5 min of nutritive suction to a standard pumping protocol significantly increases early milk removal in the first 4 days postpartum. This simple adjustment is particularly effective in the first 2 days, when colostrum volumes are low. Optimizing early pumping strategies may improve access to colostrum and support lactation initiation in mothers ...
Theresia Margaretha Nicole Manshanden, Danielle Kaye Prime, Fedde Scheele, Joost Velzel   +3 more
wiley   +1 more source

Next-generation intranasal influenza vaccines: mechanisms, platforms, and translational progress. [PDF]

Front Immunol
Reis LR, Ross TM.
europepmc   +1 more source

Prenatal and childhood exposure to smoking and retinal nerve fibre layer thickness: A meta‐analysis of three independent birth cohorts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine retinal nerve fibre layer (RNFL) characteristics in relation to prenatal and postnatal smoking exposure in three independent birth cohorts: two Danish and one Australian cohort. Methods A combined meta‐analysis of peripapillary retinal nerve fibre thickness in the Copenhagen Prospective Studies on Asthma in Childhood 2000 ...
Linna Zhu, Inger Christine Munch, Samantha Sze‐Yee Lee, David A. Mackey, Tamo Sultan, Klaus Bønnelykke, Bo Chawes, Michael Larsen, Nicklas Brustad   +8 more
wiley   +1 more source

A Phase 1, Open-Label, Randomized Study to Investigate the Pharmacokinetics and Safety of Multiple Doses of Intranasal Naloxone in Healthy Participants. [PDF]

Clin Transl Sci
Cassie D, Warnock B, Akhtar F, McCloskey D, Wyatt D.   +4 more
europepmc   +1 more source

The Efficacy and Safety of Intranasal Dexmedetomidine Spray Followed by Nitrous Oxide for Paediatric Oral Procedures. [PDF]

Int Dent J
Xiao YJ, Zhang HY, Nie MD, Liu GS, Peng W, Zhao JH, Hu ZH, Sun H, Wu Y.   +8 more
europepmc   +1 more source

Intranasal Administration of Mammary Tumour Milk Factor [PDF]

British Journal of Cancer, 1949
openaire   +2 more sources