Results 191 to 200 of about 59,442 (261)

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Combating respiratory diseases with mucosal vaccines. [PDF]

J Virol
Tang PCH, Ling Z, Lee M, King NJC, Mahalingam S.   +4 more
europepmc   +1 more source

Real‐world outcomes of zavegepant use in a tertiary care setting using the Migraine Treatment Optimization Questionnaire‐5

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background The introduction of calcitonin gene‐related peptide antagonists has transformed migraine care. Zavegepant, a third‐generation intranasal gepant, offers a nonoral treatment option for acute migraine. Although clinical trials support its efficacy and safety, real‐world data are limited.
Eric Dunn, Bradley Ong, Harpreet Kaur, Roman Popov, Claire Sonneborn, Aarushi Suneja   +5 more
wiley   +1 more source

Intranasal natural products for influenza treatment: a systematic review and meta-analysis of preclinical studies. [PDF]

Front Immunol
Zhang K, Lu Y, Yang J, Shi C, Zhao N, He X, Lu C, Li L.   +7 more
europepmc   +1 more source

Reconstruction of native cellular microanatomy in a novel bioengineered full thickness human nasal mucosal construct

Journal of Anatomy, EarlyView.
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury, Bethany Dickson, Nicola Curtis, David Bunton, Kirsty Goncalves, Stefan Przyborski   +5 more
wiley   +1 more source

Factors Associated With High Pain Scores During Paediatric Peripherous Intravenous Cannulation Insertion: A Secondary Analysis of a Prospective Cohort Study in Children

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim PIVC insertion can be a painful procedure, but limited research focuses on contributors and alleviators of pain. This study aimed to determine participant, proceduralist, and/or situational factors associated with a high pain score in children.
Amy L. Sweeny, Shane George, Clayton Lam, Bianca Goucher, Stuart Watkins, Lucy Dunstan, Peter J. Snelling   +6 more
wiley   +1 more source

Toward an NGF-based therapy for Rett syndrome. [PDF]

Front Neurosci
Borgonovo G, Tiberi A, Capsoni S, Cattaneo A.   +3 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Intranasal drug delivery: Unlocking the nose-to-brain route for central nervous system therapies. [PDF]

Int J Pharm X
Alwali B, Parumasivam T, Al-Tabakha MM.
europepmc   +1 more source