Results 241 to 250 of about 65,774 (303)

Glycerol-mediated nose-to-brain codelivery of anti-IL-17 and anti-CD73 antibodies enhances immunotherapy for melanoma brain metastases. [PDF]

Sci Adv
Yang X, Yang H, Xu N, Zhu Y, Yun Z, Zhang H, Miao J, Xie Y, Gao L, Ying L, Dong L, Wang Y, Ni Y, Xie J.   +13 more
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Combating respiratory diseases with mucosal vaccines. [PDF]

J Virol
Tang PCH, Ling Z, Lee M, King NJC, Mahalingam S.   +4 more
europepmc   +1 more source

Intranasal natural products for influenza treatment: a systematic review and meta-analysis of preclinical studies. [PDF]

Front Immunol
Zhang K, Lu Y, Yang J, Shi C, Zhao N, He X, Lu C, Li L.   +7 more
europepmc   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

Intranasal drug delivery: Unlocking the nose-to-brain route for central nervous system therapies. [PDF]

Int J Pharm X
Alwali B, Parumasivam T, Al-Tabakha MM.
europepmc   +1 more source

Comparative efficacy and post-discharge adverse events of intranasal dexmedetomidine combined with different oral medications for procedural sedation in children: a randomized controlled trial. [PDF]

Front Pharmacol
Li H, Zhou D, Du M, Xu Y.
europepmc   +1 more source

The Molecular Basis of Partial Reversal or Significant Slowing of ALS, Parkinson's Disease, and Lewy Body Dementia by Mesenchymal Exosomes/Secretome. [PDF]

Int J Mol Sci
Prodromos CC, Del Villar R, Striegel A, Pena G, Dixit R.   +4 more
europepmc   +1 more source

Intranasal Vaccine Adjuvants and Delivery Platforms: From Barrier Mechanisms to Clinical Translation. [PDF]

Vaccines (Basel)
Yao S, Zhai Z, Liao L, Zhong L, Shi C, Cheng YX, Liu X.   +6 more
europepmc   +1 more source