Results 261 to 270 of about 65,774 (303)

Intranasal Administration

Journal of the American College of Toxicology, 1994
The intranasal route has gained increased popularity in the pharmaceutical industry in recent years, particularly because of the number of new peptide therapeutic agents. This has led to a corresponding increase in both interest in and performance of toxicity (or as they are called in the pharmaceutical industry, safety assessment) studies by this ...
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Efficacy of intranasal administration of neostigmine in myasthenic patients

Journal of Neurology, 1992
The efficacy of intranasally administered neostigmine was tested in 22 patients with generalized myasthenia gravis (MG). Topical therapy to the highly vascularized oropharynx proved to be quickly effective in 5-15 min both clinically and electrophysiologically.
A, Sghirlanzoni, D, Pareyson, C, Benvenuti, G, Cei, V, Cosi, M, Lombardi, M, Nicora, R, Ricciardi, F, Cornelio   +8 more
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Intranasal administration of deferoxamine to iron overloaded patients

The American Journal of the Medical Sciences, 1989
We examined the effect of intranasal administration of deferoxamine on iron excretion in seven patients with iron overload secondary to chronic transfusion therapy. Deferoxamine was administered in doses of 0.75 to 3.0 gm given over 12 hours in a variety of dosing schedules.
G S, Gordon, D R, Ambruso, W A, Robinson, J H, Githens   +3 more
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The Intranasal Route as an Alternative Method of Medication Administration

Critical Care Nurse, 2018
Intranasal drug administration is a less invasive method of drug delivery that is easily accessible for adult and pediatric patients. Medications administered by the intranasal route have efficacy comparable to intravenous administration and typically have superior efficacy to subcutaneous or intramuscular routes.
Calvin, Tucker, Lyn, Tucker, Kyle, Brown
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The effect of intranasal administration of oxytocin on fear recognition

Neuropsychologia, 2010
The oxytocinergic system has recently been placed amongst the most promising targets for various psychiatric treatments due to its role in prosocial behavior and anxiety reduction. Although recent studies have demonstrated a general effect of administration of oxytocin on emotion recognition, no study to date has examine the effect of oxytocin on each ...
M, Fischer-Shofty, S G, Shamay-Tsoory, H, Harari, Y, Levkovitz   +3 more
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Intranasal administration of midazolam to a severely burned child

Burns, 1990
This report describes the use of intranasally administered midazolam for sedation in a critically ill burned paediatric patient without venous access. Placement of a central venous catheter was successfully carried out following sedation by this method.
T L, Rice, J V, Kyff
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Pharmacokinetics and Pharmacodynamics of Midazolam After Intranasal Administration

The Journal of Clinical Pharmacology, 1997
This study aimed to characterize the pharmacokinetics and pharmacodynamics of midazolam after intranasal administration to healthy volunteers. Eight participants were given 0.25 mg/kg intranasally and 2 mg intravenously in a randomized, crossover fashion.
A H, Burstein, R, Modica, M, Hatton, A, Forrest, F M, Gengo   +4 more
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Intranasal administration of desmopressin acetate (DDAVP) to hemophiliacs

Thrombosis Research, 1980
Abstract The intravenous infusion of desmopressin acetate (DDAVP), a synthetic vasopressin analogue, has been shown to cause a sustained increase in all Factor VIII related properties (VIII-C, VIIIR-Ag, VIIIR-WF) in patients with mild to moderate hemophilia and von Willebrand's disease. This study examines the effect of high doses of intranasal DDAVP
D L, Dewald, B, Briggs, R E, Smith
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Accidental intranasal administration of phenol.

Veterinary and human toxicology, 1999
A 79-y-old man developed erythema and superficial sloughing of the turbinate following accidental intranasal administration of 89.2% phenol solution. Previous documented reports of phenol exposure include exposures via dermal and oral routes, but no reports of nasal phenol administration were found.
L F, Durback-Morris, E J, Scharman
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Intranasal Administration of Nitroglycerin

Anesthesiology, 1981
A B, Hill, C J, Bowley, M L, Nahrwold, P R, Knight, M M, Kirsh, J K, Denlinger   +5 more
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