Results 121 to 130 of about 5,122,356 (332)

Placebo Effect Sizes in Clinical Trials of Knee Osteoarthritis Using Intra‐Articular Injections of Biologic Agents

open access: yesArthritis Care &Research, EarlyView.
Objective Patients with knee osteoarthritis rely on symptomatic treatments, in which up to 75% of the pain reduction can be attributed to the placebo effect. This effect may vary based on treatment type (eg, biologics vs nonbiologic injection) and route of administration (eg, intra‐articular vs topical vs oral).
Johanna M. Borst   +5 more
wiley   +1 more source

Effect of henbane seed on acute and chronic painin male rats [PDF]

open access: yes
Introduction: Recent studies have shown that anticholinergic alkaloid compounds have antinociceptive property. Regarding to the presence of anticholinergic alkaloid compounds in henbane (hyoscyamus niger) and due to the expressing of this plant as ...
خلیلی, محسن   +2 more
core  

Elevated central serotonin levels inhibit emotional crying [PDF]

open access: yes, 2010
Previous research has suggested a possible role of serotonin in emotional expressions, such as crying. We have found that a transient increase of central serotonin levels by means of oral administration of paroxetine reduces crying in response to ...
Ad Vingerhoets   +3 more
core   +1 more source

Prevention of Adiposity by the Oral Administration of ?-Cryptoxanthin [PDF]

open access: yesFrontiers in Neurology, 2011
β-Cryptoxanthin (β-CRX) is a carotenoid found in human blood. It is specifically rich in Satsuma mandarin (Citrus unshiu Marc.) but very little in other fruits or vegetables. Several reports indicate the health promoting benefits of β-CRX. As we had reported visceral fat reduction on mildly obese male by the oral administration of β-CRX, a detailed ...
openaire   +3 more sources

Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine.

open access: yesNew England Journal of Medicine, 2007
BACKGROUND Advanced gastric cancer can respond to S-1, an oral fluoropyrimidine. We tested S-1 as adjuvant chemotherapy in patients with curatively resected gastric cancer.
S. Sakuramoto   +13 more
semanticscholar   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry   +2 more
wiley   +1 more source

Ramsay Hunt syndrome a case report and review of literature [PDF]

open access: yes, 2013
This is a case report of a rather rare disorder i.e. Ramsay Hunt syndrome.  This is caused by Varicella zoster infections involving geniculate ganglion of facial nerve.  This syndrome is manifested by the presence of blebs in the external auditory canal,
Thiagarajan, Balasubramanian
core   +1 more source

Self-administration of edible Δ9-tetrahydrocannabinol and associated behavioral effects in mice [PDF]

open access: yes, 2019
Background With increasing access to legal cannabis across the globe, it is imperative to more closely study its behavioral and physiological effects.
Boehm, Stephen L., II   +3 more
core   +1 more source

Adherence to disease-modifying treatments in patients with multiple sclerosis in Spain

open access: yesPatient Preference and Adherence, 2019
Ramón Morillo Verdugo,1 Esther Ramírez Herráiz,2 Raquel Fernández-Del Olmo,3 Montserrat Roig Bonet,4 María Valdivia García51Valme University Hospital, Seville, Spain; 2La Princesa University Hospital, Madrid ...
Morillo Verdugo R   +4 more
doaj  

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri   +7 more
wiley   +1 more source

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