Results 1 to 10 of about 1,812,803 (254)

Pharmacokinetics and pharmacodynamics of propranolol in hypertensive patients after sublingual administration: systemic availability

Brazilian Journal of Medical and Biological Research, 1998
The bioavailability of propranolol depends on the degree of liver metabolism. Orally but not intravenously administered propranolol is heavily metabolized.
A.P. Mansur, S.D. Avakian, R.S. Paula, H. Donzella, S.R.C.J. Santos, J.A.F. Ramires   +5 more
doaj   +2 more sources

Sublingual Nitroglycerin Administration to Relieve Radial Artery Vasospasm and Retrieve Wedged Catheter: A Consideration in Neuroangiography

Stroke: Vascular and Interventional Neurology, 2022
Background Radial artery spasm is a common hinderance during transradial approaches for neuroangiography. Ways of alleviation have been described, including patient sedation, local lidocaine, or even prophylactic administration of intra‐arterial ...
Asad S. Akhter, Richard Gumina, Shahid Nimjee   +2 more
doaj   +2 more sources

Sublingual administration of liposomes enclosing alpha-galactosylceramide as an effective adjuvant of allergen immunotherapy in a murine model of allergic rhinitis

Allergology International, 2019
Background: Sublingual immunotherapy (SLIT) is an established efficacious approach for the treatment of allergic rhinitis (AR). However, SLIT requires a long administration period to establish stable and adequate responses.
Satoshi Suzuki, Daiju Sakurai, Toshioki Sakurai, Syuji Yonekura, Tomohisa Iinuma, Yusuke Okuma, Fumie Ihara, Tomoyuki Arai, Toyoyuki Hanazawa, Emi Fukuda-Kawaguchi, Yasuyuki Ishii, Yoshitaka Okamoto   +11 more
doaj   +1 more source

Use of Mifepristone and Sublingual Misoprostol for Early Medical Abortion

Taiwanese Journal of Obstetrics & Gynecology, 2006
Objective: Existing drug-induced abortion techniques involve oral administration of 200 mg of mifepristone, followed by oral administration of 600 mg of misoprostol 48 hours later, but the effects are variable.
Mau Lin, Yiu-Tai Li, Fu-Min Chen, Shu-Fang Wu, Ching-Wan Tsai, Tien-Hui Chen, Tsung-Cheng Kuo   +6 more
doaj   +1 more source

Effectiveness and safety of sublingual misoprostol in medical treatment of the 1st trimester miscarriage: experience of off-label use in Korea [PDF]

Obstetrics & Gynecology Science, 2018
ObjectiveThis study was conducted to determine the effectiveness and safety of medical treatment with sublingual misoprostol (MS) in the 1st trimester miscarriage under the approval by Health Insurance Review and Assessment Service (HIRA) for off-label ...
Jung Yeon Park, Hyo Jeong Ahn, Ba Raem Yoo, Kyu Ri Hwang, Taek Sang Lee, Hye Won Jeon, Sun Min Kim, Byoung Jae Kim   +7 more
doaj   +1 more source

Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease

Clinical and Translational Science, 2021
Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine ...
Felix Agbo, Ryan L. Crass, Yu‐Yuan Chiu, Sunny Chapel, Gerald Galluppi, David Blum, Bradford Navia   +6 more
doaj   +1 more source

Sublingual Tablets and the Benefits of the Sublingual Route of Administration

Journal of Pharmaceutical Research, 2017
Purpose : Sublingual drug delivery can be an alternative and better route when compared to oral drug delivery as sublingually administered dosage forms bypass hepatic metabolism. A rapid onset of pharmacological effect is often desired for some drugs, especially those used in the treatment of acute disorders. Sublingual tablets disintegrate rapidly and
Arshad Bashir Khan, Tarun Kingsley, Preeta Caroline   +2 more
openaire   +1 more source

Sublingual Vaccination with Live Influenza Virus Induces Better Protection Than Oral Immunization in Mice

Life, 2022
Both sublingual (SL) and oral vaccine administration modalities are convenient, easy, and safe. Here, we have investigated the differences in vaccine efficacy that are induced by oral and sublingual immunization with live influenza virus (A/Hong Kong/1 ...
Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Hae-Ji Kang, Ki-Back Chu, Fu-Shi Quan   +5 more
doaj   +1 more source

The combination route versus sublingual and vaginal misoprostol for the termination of 13 to 24 week pregnancies: A randomized clinical trial

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: The goal of this study was to compare the effectiveness of misoprostol via sublingual and vaginal administration versus the combination route in the termination of 13 to 24 week pregnancies.
Fatemeh Rahimi-Sharbaf, Khadijeh Adabi, Mehrnaz Valadan, Mahboobeh Shirazi, Sepideh Nekuie, Parisa Ghaffari, Narges Khansari   +6 more
doaj   +1 more source

Evaluation of the sublingual route for administration of influenza H5N1 virosomes in combination with the bacterial second messenger c-di-GMP. [PDF]

PLoS ONE, 2011
Avian influenza A H5N1 is a virus with pandemic potential. Mucosal vaccines are attractive as they have the potential to block viruses at the site of entry, thereby preventing both disease and further transmission.
Gabriel Kristian Pedersen, Thomas Ebensen, Ingrid Hjetland Gjeraker, Signe Svindland, Geir Bredholt, Carlos Alberto Guzmán, Rebecca Jane Cox   +6 more
doaj   +1 more source