Premedication of Pediatric Cardiac Population with Midazolam: Comparison of Oral and Sublingual Administration Regarding Plasma Midazolam Concentration, Clinical Effectiveness, Hemodynamic and Behavioral Outcomes [PDF]
ChildrenBackground: Midazolam is widely used as a pediatric premedication, but evidence from direct comparisons of oral and sublingual administration in children with congenital heart disease remains limited, particularly that from pharmacokinetic and ...
Theofili Kousi +9 more
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Development of Sedative Dexmedetomidine Sublingual In Situ Gels: In Vitro and In Vivo Evaluations
Pharmaceutics, 2022 Intravenous dexmedetomidine (DEX) is currently approved by the FDA for the sedation of intubated patients in intensive care units to reduce anxiety and to augment postoperative analgesia.
Ayat A. Allam +10 more
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Brazilian Journal of Medical and Biological Research, 1998 The bioavailability of propranolol depends on the degree of liver metabolism. Orally but not intravenously administered propranolol is heavily metabolized.
A.P. Mansur +5 more
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Stroke: Vascular and Interventional Neurology, 2022 Background Radial artery spasm is a common hinderance during transradial approaches for neuroangiography. Ways of alleviation have been described, including patient sedation, local lidocaine, or even prophylactic administration of intra‐arterial ...
Asad S. Akhter +2 more
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Sublingual NMN administration increases early circulating terminal catabolites 2PY and 4PY compared with oral administration in healthy adult men [PDF]
Scientific ReportsSublingual administration of nicotinamide mononucleotide (NMN) is hypothesized to enhance systemic bioavailability by bypassing hepatic first-pass metabolism, a significant limitation of oral intake.
Jun Wakabayashi +2 more
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Hyperpyrexia with hemodynamic instability after sublingual misoprostol: case report and literature review [PDF]
AJOG Global ReportsMisoprostol is widely used in obstetric practice for the prevention and treatment of postpartum hemorrhage due to its uterotonic efficacy, oral administration, and stability at room temperature. Although generally considered safe, rare but severe adverse
Paola A. Castellanos, MD +3 more
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Sublingual vs. vaginal misoprostol for cervical preparation before surgical abortion in the first trimester [PDF]
New Indian Journal of OBGYN, 2023 Background: Suction evacuation is the most common surgical method of first-trimester pregnancy termination and cervical dilatation is the most critical step.
Neeru Malik +5 more
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Administration of Misoprostol Sublingual versus Vaginal for the Termination of Second Trimester Missed Miscarriage [PDF]
Zagazig University Medical Journal, 2021 Background: miscarriage is the process of fetus extraction (embryo) weighting less than 500 mg equivalent to approximately 20 to 22 weeks gestation. Misoprostol is increasingly used for second trimester termination of pregnancy. It is inexpensive, and it
Mustafa Abdel Fatah +3 more
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Comparative study of sublingual versus vaginal misoprostol following mifepristone in early first trimester medical termination of pregnancy - a prospective study [PDF]
New Indian Journal of OBGYN, 2019 Aim: To compare the efficacy and side effects of sublingual versus vaginal administration of misoprostol after a single oral dose of 200 mg of mifepristone in termination of early first trimester pregnancy. Methods: This is a randomised prospective study
B. L Pathak, Shikha Hajong Roy
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Use of Mifepristone and Sublingual Misoprostol for Early Medical Abortion
Taiwanese Journal of Obstetrics & Gynecology, 2006 Objective: Existing drug-induced abortion techniques involve oral administration of 200 mg of mifepristone, followed by oral administration of 600 mg of misoprostol 48 hours later, but the effects are variable.
Mau Lin +6 more
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