Results 11 to 20 of about 34,531 (282)

Sublingual immunotherapy: administration, dosages, use. [PDF]

International journal of immunopathology and pharmacology, 2009
Allergen extracts for sublingual immunotherapy (SLIT) are currently marketed by several manufacturers, with administration schedules and amount of allergen(s) quite variable in the different products, although almost all are standardized biologically or immunologically.
Frati, F, LA GRUTTA, Stefania, Bernardini, R, Zampogna, S, Scurati, S, Puccinelli, P, Riario Sforza, G, Incorvaia, C.   +7 more
core   +6 more sources

Expanding the therapeutic landscape of minoxidil for androgenetic alopecia: topical, oral and sublingual formulations [PDF]

Frontiers in Pharmacology
Androgenetic alopecia (AGA) is the most common form of non-scarring alopecia, affecting up to 80% of men and 50% of women by the age of 70. Minoxidil, initially developed as an oral antihypertensive, has become one of the most widely used therapies for ...
Flavia Rodrigues Dias, Shin Shen Yong, Shin Shen Yong, Holly FitzGerald, Rodney D. Sinclair, Bevin Bhoyrul   +5 more
doaj   +2 more sources

Single-Dose Pharmacokinetic Assessment of TNX-102 SL (Cyclobenzaprine HCl Sublingual Tablets): Results From Randomized, Open-Label Studies in Healthy Volunteers. [PDF]

Clin Pharmacol Drug Dev
Abstract Daily oral cyclobenzaprine hydrochloride (HCl) has provided transient benefits in fibromyalgia, a chronic pain condition. To improve this effect, we evaluated sublingual formulations designed to drive transmucosal absorption. Two open‐label studies evaluated the pharmacokinetics (PK), tolerability, and relative bioavailability of sublingual ...
Daugherty BL, Meibohm B, Sullivan GM, Gould EM, Lederman S.   +4 more
europepmc   +2 more sources

Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis [PDF]

Frontiers in Pharmacology
BackgroundVitamin B12 deficiency is a widespread condition, particularly among elderly individuals, patients with malabsorption syndromes, and those following plant-based diets.
Marta Mazur, Marta Mazur, Artnora Ndokaj, Claudia Salerno, Claudia Salerno, Jessica Vallone, Roman Ardan, Sabina Bietolini, Florence Carrouel, Aleksandra Wilk, Rachel Sarig, Livia Ottolenghi, Denis Bourgeois   +12 more
doaj   +2 more sources

Asenapine for delirium in patients with cancer: A scoping review. [PDF]

PCN Rep
Abstract This scoping review mapped the existing literature on the application of asenapine for delirium management in patients with cancer, including prevention and treatment, while summarizing current research trends. The review followed the methodological framework proposed by Arksey and O'Malley and was reported in accordance with the Preferred ...
Ishida T, Kobayakawa M, Kako J, Matsuda Y, Sadahiro R, Tanimukai H.   +5 more
europepmc   +2 more sources

Correlations Between Rheology, In Situ Mucosal Retention and In Vivo Immunogenicity Reveal the Potential and Limitations of Mucoadhesive Excipients for Sublingual Vaccine Delivery [PDF]

Pharmaceutics
Background/Objectives: Sublingual vaccination offers a non-invasive route for inducing both systemic and mucosal immunity, yet the formulation properties that govern its success remain poorly defined.
Mohamed Deifallah Yousif, Ilona Kubajewska, Fatme Mawas, Sudaxshina Murdan   +3 more
doaj   +2 more sources

A Randomized, Double-Blinded, Placebo-Controlled, Cross Over Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine [PDF]

, 2020
Introduction. Daily oral beta-adrenoreceptor antagonist has been shown to be effective in preventing migraine headaches. Timolol 0.5% ophthalmic solution is a non-selective beta-adrenoreceptor antago- nist, where the primary use is for glaucoma.
Aggarwal, Dipika, Barohn, Richard J., Bittel, Brennen, Dubinsky, Richard, Ford, Deetra, Gronseth, Gary, Hairston, Vernita, Heim, Andrew J., Herbelin, Laura, Landazuri, Patrick, Sachen, Fred   +10 more
core   +2 more sources

Pharmacokinetics of repeated doses of misoprostol [PDF]

, 2009
BACKGROUNDMisoprostol is widely used in obstetrics and gynaecology for medical abortion, cervical priming and induction of labour. To aid the design of effective and safe regimens, we have investigated the pharmacokinetic parameters after the vaginal or ...
Ho, PC, Lee, SWH, Schweer, H, Tang, OS
core   +1 more source

The future outlook on allergen immunotherapy in children: 2018 and beyond. [PDF]

, 2018
Allergen immunotherapy (AIT) is the only currently available immune-modifying and aetiological treatment for patients suffering from IgE-mediated diseases.
Arasi S, Corsello G, Pajno GB, Villani A
core   +2 more sources

Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development. [PDF]

Trop Med Int Health
ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Nafade V, Sule NO, Zhang Y, Sassi A, Basta NE.   +4 more
europepmc   +2 more sources