Results 161 to 170 of about 324,570 (328)

MixEHR-Nest: Identifying Subphenotypes within Electronic Health Records through Hierarchical Guided-Topic Modeling [PDF]

arXiv
Automatic subphenotyping from electronic health records (EHRs)provides numerous opportunities to understand diseases with unique subgroups and enhance personalized medicine for patients. However, existing machine learning algorithms either focus on specific diseases for better interpretability or produce coarse-grained phenotype topics without ...
arxiv  

Active Learning‐Driven Discovery of Sub‐2 Nm High‐Entropy Nanocatalysts for Alkaline Water Splitting

Advanced Functional Materials, EarlyView.
High‐entropy nanoparticles (HENPs) hold great promise for electrocatalysis, yet optimizing their compositions remains challenging. This study employs active learning and Bayesian Optimization to accelerate the discovery of octonary HENPs for hydrogen and oxygen evolution reactions.
Sakthivel Perumal, Da Bean Han, Thandapani Marimuthu, Taewaen Lim, Hyun Woo Kim, Junhyeok Seo   +5 more
wiley   +1 more source

Using Recycled Materials in a Novel Dual Binder System for Hard Carbon Anodes: Closing the Loop Toward Sustainable Li‐/Na‐ion Batteries

Advanced Functional Materials, EarlyView.
The study explores for the first time the use of polyvinyl butyral (PVB), particularly recycled PVB, as a sustainable binder for Li/Na‐based electrodes in the framework of the H2020 SUNRISE EU project. Findings revealed that electrodes bound with a sustainable PAA/PVB mixture demonstrated exceptional rate capability and high initial Coulombic ...
Hamideh Darjazi, Alessandro Piovano, Giuseppina Meligrana, Giuseppe A. Elia, Claudio Gerbaldi   +4 more
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Quantum Emitters in Hexagonal Boron Nitride: Principles, Engineering and Applications

Advanced Functional Materials, EarlyView.
Quantum emitters in hexagonal boron nitride have emerged as a promising candidate for quantum information science. This review examines the fundamentals of these quantum emitters, including their level structures, defect engineering, and their possible chemical structures.
Thi Ngoc Anh Mai, Md Shakhawath Hossain, Nhat Minh Nguyen, Yongliang Chen, Chaohao Chen, Xiaoxue Xu, Quang Thang Trinh, Toan Dinh, Toan Trong Tran   +8 more
wiley   +1 more source

The Persistence of Contrarianism on Twitter: Mapping users' sharing habits for the Ukraine war, COVID-19 vaccination, and the 2022 Midterm Elections [PDF]

arXiv
Empirical studies of online disinformation emphasize matters of public concern such as the COVID-19 pandemic, foreign election interference, and the Russo-Ukraine war, largely in studies that treat the topics separately. Comparatively fewer studies attempt to relate such disparate topics and address the extent to which they share behaviors.
arxiv  

Mg2+/Al3+ Co‐doped Li‐Rich Manganese‐Based Oxides for Boosting Rate Performance and Stability of Lithium‐Ion Batteries

Advanced Functional Materials, EarlyView.
The co‐doping strategy can effectively address the challenges associated with LRMOs cathode materials, providing a promising pathway for the development of high energy density and resilient cathode materials in the next‐generation lithium‐ion batteries. Abstract Lithium‐rich manganese‐based oxides (LRMOs) are promising cathode materials for lithium‐ion
Junxia Meng, Wenzhuan Hu, Quanxin Ma, Zhenzhen Wu, Lishuang Xu, Jie Huang, Chen Xiao, Junru Wang, Lina Zhang, Feng Liu, Xing Zhi, Shanqing Zhang   +11 more
wiley   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Antioxidant and Anti‐Senescence Polyvinyl Alcohol‐Gallic Acid Supramolecular Hydrogels for Stem Cell Culture

Advanced Healthcare Materials, EarlyView.
The PVA‐GA hydrogel is formed through hydrogen bonding between PVA hydroxyl groups and GA galloyl units, enabling sustainable GA release and its extended biological activity. The hydrogel scavenges ROS to reduce oxidative stress, preventing mitochondrial damage from excessive ROS, mitigating hADSC senescence, and preserving VEGF secretion, offering a ...
Yiduo Zhou, Matías L. Picchio, Yan Nie, Lei Wang, Oihane Sanz, Yue Liu, Xun Xu, Lukas Prantl, Oliver Felthaus, Weiwei Wang, Marcelo Calderón, Nan Ma   +11 more
wiley   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source