Results 291 to 300 of about 2,597,047 (329)

Topical administration of racemic ibuprofen

Chirality, 1997
In vitro experiments to investigate possible stereoselective aspects of the topical administration of ibuprofen have been conducted. Incubation of ibuprofen with rat skin homogenates in the presence of coenzyme A, ATP, and magnesium provided no evidence for the formation of ibuprofenyl coenzyme A (the initial intermediate in the metabolic inversion of [
Paul S. Collier, Jeffrey S. Millership
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TOPICAL ADMINISTRATION OF MEDICATIONS IN THE LUNGS

Journal of Clinical Pharmacy and Therapeutics, 1983
A survey has been carried out in Zimbabwe to gain information on pharmacist attitudes and current practice involving patient education in the use of medications for topical administration in the lung. The results of the survey indicated that although there was awareness of patient misuse of the administration devices, most pharmacists did not commonly ...
McElnay, James, Summers, R.S.
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Optimal Frequency of Topical Prednisolone Administration

Archives of Ophthalmology, 1979
The relationship between the frequency with which 0.125% and 1.0% prednisolone acetate ophthalmic suspensions are instilled and the anti-inflammatory effect they achieve in the cornea was studied. Within the time limits of the experimental protocol, application of the drug at four-hour intervals failed to produce an effect while hourly administration ...
Howard M. Leibowitz, Allan Kupferman
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Correct administration of topical eye treatment

Nursing Standard, 2003
Although eye treatment is an important aspect of patient care, nurses may not always be aware of the implications of inadequate treatment of ophthalmic conditions. Topical eye treatments, including eye drops and ointments, are governed by the same controls as medication administered by other routes.
Janet Marsden, Mary Shaw
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Thermosensitive Gels for the Topical Administration of Diltiazem

Journal of Dispersion Science and Technology, 2011
In the present work, thermosensitive systems were prepared, characterized, and proposed for diltiazem administration in the topical treatment of anal fissures. Methylcellulose and PluronicF127 were used as gelling polymers. Some low-toxicity molecules, such as sodium glycocholate, citric acid, and lactic acid, were added to gel formulations as ...
CHIRIO, Daniela, TROTTA, Michele, GALLARATE, Marina, PEIRA, Elena, CARLOTTI, Maria Eugenia   +4 more
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Hazards of topical ophthalmic drug administration [PDF]

Trends in Anaesthesia and Critical Care, 2011
Summary A wide range of topical ophthalmic drugs is available for use to provide a complete eye examination or a decrease in intraocular pressure or optimum conditions for many surgical procedures, but administration of these drugs is not free from the risks of serious adverse events.
Oya Yalcin Cok, Berrin Günaydin
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Severe anaphylactic reaction to topical administration of framycetin [PDF]

Journal of Allergy and Clinical Immunology, 1995
themselves might contr ibute to some of the measured IL-5. However , taking into account the in vitro data and the respective t ime courses of serum IL-5 and blood eosinophils, it is likely that most IL-5 or iginated f rom T cells. In teres t ingly, hypereosinophi l ia re lated to IL-5 secret ion by helper T cells was previously demons t ra ted in pos ...
Frank K. Jugert, Hans F. Merk, Helmut Gall, Thomas M. Proebstle   +3 more
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Doxepin Toxicity in a Child Following Topical Administration

The Annals of Pharmacotherapy, 2000
OBJECTIVE: To describe a case of a child with altered mental status following the topical administration of doxepin. CASE SUMMARY: A five-year-old Hispanic girl was brought to the emergency department because she was difficult to arouse at school.
Katharina Spiegel, Adam Negrusz, Michele Zell-Kanter, Theodore S Toerne   +3 more
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Is the Safety of Finasteride Correlated With Its Route of Administration: Topical Versus Oral? A Pharmacovigilance Study With Data From the United States Food and Drug Administration Adverse Event Reporting System

International Journal of Dermatology
The United States Food and Drug Administration (FDA) approved oral finasteride for androgenetic alopecia. In 2022, approximately 2.6 million U.S. men used it for hair loss and prostate conditions.
Aditya K. Gupta, M. Talukder, Sharon A. Keene, M. Bamimore   +3 more
semanticscholar   +1 more source

Antihistamines: topical vs oral administration

Clinical & Experimental Allergy, 1996
SummaryThe pathogenesis of allergic rhinitis is complex, involving not only histamine and mast cell‐derived tryptase, but also eosinophil‐ and neutrophil‐derived mediators, cytokines, and intercellular cell adhesion molecules (ICAM‐1). It is surprising that antihistamines, which block only one component of the process, have proved so effective in the ...
J. H. Wang, R. N. McCABE, M. A. Calderon, Robert J. Davies, A. C. Bagnall   +4 more
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