Results 81 to 90 of about 2,569,039 (267)

Topical Administration of GLP-1 Receptor Agonists Prevents Retinal Neurodegeneration in Experimental Diabetes

Diabetes, 2015
Retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). Since glucagon-like peptide 1 (GLP-1) exerts neuroprotective effects in the central nervous system and the retina is ontogenically a brain-derived tissue, the ...
C. Hernández, P. Bogdanov, L. Corraliza, M. García-Ramírez, Cristina Solà-Adell, J. A. Arranz, A. Arroba, Á. Valverde, R. Simó   +8 more
semanticscholar   +1 more source

Episcleral Venous Pressure and the Ocular Hypotensive Effects of Topical and Intracameral Prostaglandin Analogs. [PDF]

, 2019
There is a limit beyond which increasing either the concentration of a prostaglandin analog (PGA) or its dosing frequency fails to produce increases in ocular hypotensive efficacy with topical dosing.
Alm, Blondeau, Brubaker, Celebi, Chen, Cymbor, Eveleth, Foroozan, Friberg, Funk, Funk, Katz, Krieglstein, Lee, Lee, Lee, Lewis, Lindén, Lovering, McDougal, Nagasubramanian, Ogundele, Phelps, Prum, Seal, Selbach, Selbach, Sherwood, Sit, Sit, Strohmaier, Tsai, Walløe, Watts, Wilke, Zamora, Zamora   +36 more
core   +2 more sources

Topical Administration of Ibuprofen for Injured Athletes: Considerations, Formulations, and Comparison to Oral Delivery

Sports Medicine - Open, 2017
Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of drugs commonly used to treat both the acute and chronic injuries sustained by athletes during training and competition. In many parts of the world, NSAIDs can be purchased over-the-counter and
M. Manoukian, C. Migdal, Amode R. Tembhekar, Jerad A. K. Harris, C. Demesa   +4 more
semanticscholar   +1 more source

Pushing Your Point of View: Behavioral Measures of Manipulation in Wikipedia [PDF]

arXiv, 2011
As a major source for information on virtually any topic, Wikipedia serves an important role in public dissemination and consumption of knowledge. As a result, it presents tremendous potential for people to promulgate their own points of view; such efforts may be more subtle than typical vandalism.
arxiv  

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission

PLoS Pathogens, 2015
Vaginal HIV transmission accounts for the majority of new infections worldwide. Currently, multiple efforts to prevent HIV transmission are based on pre-exposure prophylaxis with various antiretroviral drugs.
M. Kovárová, Olivia D Council, A. Date, Julie M. Long, Tomonori Nochii, Michael Belshan, A. Shibata, Heather Vincent, Caroline E. Baker, W. Thayer, Guenter Kraus, Sophie Lachaud-Durand, P. Williams, C. Destache, J. Victor Garcia, R. Desrosiers   +15 more
semanticscholar   +1 more source

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model

Scientific Reports
Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration effectively minimizes side effects.
Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama   +9 more
doaj   +1 more source

Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]

, 2020
Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu, Constantin, Vlad Denis, Radaschin, Diana Sabina, Stana, Paunica, Tatu, Alin Laurentiu   +4 more
core   +1 more source

Green Information Technology as Administrative innovation - Organizational factors for successful implementation: Literature Review [PDF]

arXiv, 2016
There is a considerable amount of awareness of environmental issues and corporate responsibility for sustainability. As such, from a technological viewpoint, Green IT has become an important topic in contemporary organizations. Consequently, organisations are expected to be innovative in their business practices to become more sustainable.
arxiv  

Analytical profiling, modeling and transdermal/transmucosal characteristics of bioactive N-alkylamides [PDF]

, 2009
N-alkylamides are a group of bioactive molecules found in several plants. Extracts and formulations derived from these plants are not only used orally, but are applied on the skin and buccal mucosa as well.
Baert, Bram, Blondeel, Phillip, Boonen, Jente, Burvenich, Christian, De Spiegeleer, Bart   +4 more
core   +1 more source

A Novel Model of Pain Sensation Using Superfused Gastrosplenic Omentum Preparation of Anesthetized Rats

Journal of Pharmacological Sciences, 2008
A pain model for screening analgesics was established in anesthetized rats. The omenta of urethane-anesthetized rats were exteriorized, fixed in a plastic chamber, and superfused with Tyrode solution.
Shi-Jie Yang, Makoto Katori, Masataka Majima   +2 more
doaj