Results 111 to 120 of about 9,451,716 (342)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

THE COMPETITIVENESS OF DESTINATION ROMANIA [PDF]

open access: yes
The aim of our paper is to depict the state of affairs in the Romanian tourist industry as well as to point out the necessary steps and the effective strategies in order to capitalize on the huge tourist potential of our country.
BUDICA BOGDAN   +2 more
core  

Cocaine Self-Administration and Extinction Leads to Reduced Glial Fibrillary Acidic Protein Expression and Morphometric Features of Astrocytes in the Nucleus Accumbens Core

open access: green, 2016
Michael D. Scofield   +8 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A.D.XENOPOL, A LESS KNOWN ECONOMIST [PDF]

open access: yes
Outstanding Romanian man of culture in the second half of the XIXa€™th century, known as remarkable historian, A.D.Xenopol was also a genuine economist, preoccupied not only by the theory but also by the practice of economics.
STEFANESCU FLORICA
core  

Tratamiento del estado epiléptico con diazepam por vía rectal: Rectal administration in the treatment of status epilepticus [PDF]

open access: diamond, 1990
Marcelo Devilat B   +4 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Administração, cultura e desenvolvimento

open access: yesCadernos EBAPE.BR
No Brasil, o tema "cultura" vem despertando um crescente interesse, tanto no meio acadêmico quanto nas organizações públicas públicas e privadas. Na maioria das vezes, as discussões em torno do tema têm, genericamente, dois focos principais.
Janaina Machado Simões   +1 more
doaj   +1 more source

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