Results 61 to 70 of about 3,501,089 (247)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The "Problem" of Aspects of Teaching and Learning / Teaching - Learning in European Union Law
Journal of Legal Studies, 2015 The paper addresses an important problem and the frequency of teaching and learning/teaching-learning in higher education/university student, generated by the incapacity to himself selectively information conveyed through alternative sources.
Nedelcu-Ienei Anda Veronica
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Parisians write to the Administration: Interplay between social and spatial boundaries (1920-1945)
L'Atelier du CRHThis article combines two of Isabelle Backouche’s current research topics. One is the annexation of the non aedificandi zone, a strip of land 250 meters wide where construction was banned in 1841 because it ran along the fortifications; it was largely ...
Isabelle Backouche
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Significance of Pirogov`s scientific ideas for modern organization of Public Health.
Medičnì Perspektivi, 2015 This article is about Nikolay Ivanovich Pirogov, a surgeon and anatomist, prominent scientist and educator, founder of field surgery. He was the first to learn field surgery and military administration in practice.
L. S. Semenova, U. A. Koryagin
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Education and Health PromotionManagers should have the necessary competencies to achieve organizational goals. Employees have worked with different managers and have valid opinions about managerial competencies.
Parisa Yoshari +3 more
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Tabularia, 2011 Significations of excommunication are a neglected source for administrative history, yet their diplomatic provides valuable information. This paper examines significations issued by English bishops from the dioceses of Coventry and Lichfield, Exeter ...
Philippa Hoskin
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source