Results 61 to 70 of about 7,880,769 (355)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Gouverner c’est prévoir: Foresight als ganzheitlicher Prozess zur strategischen Steuerung am Beispiel des Kantons Aargau

open access: yesYearbook of Swiss Administrative Sciences, 2013
In 2012, the Canton of Aargau launched the process for the development of its new long-term strategy 2013–2022 («Entwicklungsleitbild»). The development of a long-term planning poses a challenge for the executive authority since it involves setting the ...
Caroline Brüesch, Daniel Brändli
doaj   +1 more source

The Organization of the Judicial System in Italy

open access: yesRevista Eurolatinoamericana de Derecho Administrativo, 2020
This paper provides a complete overview of the organization of the Judicial system in Italy with the aim to examine the relationships between the various organs operating in its field. It analyzes the structure and functions of all the bodies involved in
Giuseppe Franco Ferrari
doaj   +1 more source

Researching COVID-19: A research agenda for public policy and administration scholars

open access: yesPublic Policy and Administration, 2020
Coronavirus (COVID-19) is one of the defining policy challenges of an era. In this article, we sketch some possible ways in which the public policy and administration community can make an enduring contribution about how to cope with this terrible crisis.
C. Dunlop, E. Ongaro, K. Baker
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Relato de experiência: ensinando a administração em enfermagem através da educação em saúde Ensenando la administración en enfermeria a través de la educación en salud Teaching nursing administration through health education

open access: yesRevista Brasileira de Enfermagem, 2004
Este trabalho aborda uma experiência de ensino na Disciplina de Administração em Enfermagem de uma Universidade Federal, com alunos que estão cursando o oitavo período do curso de graduação em enfermagem.
Rosangela Maria Greco
doaj   +1 more source

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