Results 191 to 200 of about 4,141,685 (285)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Improving residents' satisfaction with administrative boundary changes: A comparative analysis based on the township-town merger policy. [PDF]

PLoS One
Wang Q, Zhao H, Sun J, Yu Y, Zhang C, Hao P.   +5 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Quantifying and Understanding Healthcare Service Access for Geographically Distributed Communities: The Application of Address-Level Intelligence. [PDF]

Aust J Rural Health
Versace VL, Coffee NT, Shee AW, Blake M, Quinsey S, Wood S, Tanton R, Schroers RD, Mc Namara K, Hadfield M.   +9 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

PADI-Location-AR-EN: A normalized Arabic-English spatial entity dataset for epidemiological surveillance. [PDF]

Data Brief
El Houbri FE, Idrissi N, Roche M, Valentin S.   +3 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Adjusting for confounding in population administrative data when confounders are only measured in a linked cohort.

Int J Popul Data Sci
Silverwood RJ, Baranyi G, Calderwood L, De Stavola BL, Ploubidis GB, White IR, Harron K.   +6 more
europepmc   +1 more source

The Wealth of Wealthholders. [PDF]

Rev Income Wealth
Ameriks J, Caplin A, Lee M, Shapiro MD, Tonetti C.   +4 more
europepmc   +1 more source

Comparison of administrative and survey data for estimating vitamin A supplementation and deworming coverage of children under five years of age in Sub‐Saharan Africa

Tropical medicine & international health, 2017
A. Janmohamed, david doledec
semanticscholar   +1 more source