Results 81 to 90 of about 22,706,981 (364)

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Exploring local variation in the use of out-of-home care in England using linked administrative data

International Journal of Population Data Science, 2017
Objectives In England, approximately one in thirty children spend time in out-of-home care (OHC) by age 18.Use of OHC is known to vary across the country, which may be explained in part by ethnic group differences in the risk of being placed in OHC. This
Louise Mc Grath-Lone, Katie Harron, Lorraine Dearden, Bilal Nasim, Ruth Gilbert   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

How do you interpret a billion primary care records?

International Journal of Population Data Science, 2017
Background Research into General Practitioner (GP) records is relatively straightforward when it comes to establishing the prescribing of a particular drug or a specific disease group, but what if you want to use it to make more general inferences about ...
Martin Heaven, Laura McGinn, Sarah Lowe, Kerry Bailey, Ronan Anthony Lyons   +4 more
doaj   +1 more source

Coder perspectives on physician-related barriers to producing high-quality administrative data: a qualitative study.

CMAJ Open, 2017
BACKGROUND Professional coding specialists ("coders") are experts at translating patient chart information into alphanumerical codes, which are then widely used in research and health policy decision-making.
K. Tang, Kelsey Lucyk, H. Quan
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Global socioeconomic inequalities in vaccination coverage, supply, and confidence

npj Vaccines
Sustainable Development Goal (SDG) adopted in 2015 aim to reduce inequalities and achieve universal health coverage, including access to essential vaccines for all.
Qiang Wang, Kathy Leung, Mark Jit, Joseph T. Wu, Leesa Lin   +4 more
doaj   +1 more source

Estimating annual prevalence of depression and anxiety disorder in multiple sclerosis using administrative data

BMC Research Notes, 2017
ObjectiveResearchers have developed case definitions to estimate incidence and lifetime prevalence of depression and anxiety disorders in multiple sclerosis (MS) using administrative data.
R. Marrie, R. Walld, J. Bolton, J. Sareen, J. Walker, S. Patten, A. Singer, L. Lix, C. Hitchon, R. El‐Gabalawy, A. Katz, J. Fisk, C. Bernstein   +12 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Involving the public in transforming the data landscape in Scotland

International Journal of Population Data Science
Objective In 2023 a public panel around public sector data use in Scotland was refreshed. The aim was to have a panel not only feedback on individual research projects but also the broader systems and processes of the data landscape in Scotland – from ...
Katie Oldfield, Harriet Baird
doaj   +1 more source