Results 71 to 80 of about 570,077 (306)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Journal of Danubian Studies and Research, 2022 With the appearance and establishment of the administrative contentious, the issue of the existence of an absolute right of control of the courts over administrative acts arose.
Maria Cristiana Ieremie
doaj
Exploring the stigma of food stamps [PDF]
This paper reports on theoretical research into the effect of stigma and social norms on policy outcomes of the Food Stamp program, in particular the effect on the caseload.
E. J. Bird
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Legislation on Administrative Offenses: Reform or Modernization
Сибирское юридическое обозрение, 2017 The article examines the state of legislation on administrative offenses. The necessity of modernization, ideas and prospects for the development and adoption of a new codified legal act in the relevant legal sphere is argumented.
Aleksandr G. Avdeiko, Dmitrii A. Gazizov
doaj +1 more source
Indirect Judicial Control on Normative Administrative Acts
De Jure, 2019 The following article focuses on the controversial in theory and practice problem of the possibility for the administrative court to exercise indirect judicial control of normative administrative act. An analysis of the case law has been made and attitude have been taken.
openaire +1 more source
The Growing Influence of the Courts over the Fate of Refugees [PDF]
, 2008 A number of migration scholars suggest that domestic courts have become the key protective institution for refugees. How can we explain this claim? One prominent explanation identifies group litigation as the key source of the increasing influence of the
Soennecken, Dagmar
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
To the Question of Administrative Responsibilityfor Vagrancy and Begging
Сибирское юридическое обозрение, 2017 The article deals with the issues of modern administrative and legal regulation of counteraction to such antisocial phenomena as vagrancy and begging.
Oleg A. Dizer
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source