Results 61 to 70 of about 570,077 (306)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

President Trump's war on regulatory science [PDF]

, 2019
The Trump Administration has taken numerous actions that appear hostile to scientists, scientific research, and scientific data, leading some observers to assert that a war on science is underway.
Lin, AC
core  

Rules, Standards, and the Internal Point of View [PDF]

, 2006
Large scale structure and ...
Benítez, N., Cenarro, A.J., Chies-Santos, A.L., Chow-Martínez, M., Cibirka, N., Coelho, P., Cortesi, A., Costa Duarte, M.V., Cristobal-Hornillos, D., Cypriano, E.S., Dupke, R., Ederoclite, A., Hernández-Fernández, J.D., Hernández-Jimenez, J.A., Jimenez-Teja, Y., Leite Ribeiro, B.R., López-Sanjuan, C., Marín-Franch, A., Moles, M., Molino, A., Monteiro-Oliveira, R., Neto, G.B.L., Novais, P., Oliveira, C.M., Pereira, E., Ramió, H.Vázquez, Sampedro, L., Santos, W., Schoenell, W., Sodré, L., Varela, J.   +30 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A Continuous Theory of Income Insurance [PDF]

In this paper we treat an individual’s health as a continuous variable, in contrast to the traditional literature on income insurance, where it is regularly treated as a binary variable.
Lindbeck, Assar, Persson, Mats
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Global administrative law: the key aspects of conceptualizing [PDF]

Lex Portus, 2019
The present article provides the analyses of the main aspects of the global administrative law concept been proposed at the early 2000 to explain legal particulars of the global governance phenomenon.
Borys Kormych
doaj   +1 more source

Director Reputation, Ceo-Board Power, And The Dynamics Of Board Interlocks [PDF]

, 1996
This study advances research on CEO-board relationships, interlocking directorates, and director reputation by examining how contests for intraorganizational power can affect interorganizational ties.
Westphal, J. D., Zajac, E. J.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Administrative and Judicial Discretion in Procedural Decision Making under the Code of Administrative Offenses of the Russian Federation

Сибирское юридическое обозрение
This article continues the scholarly discussion initiated by Professors Yu. P. Solovey, P. P. Serkov, and S. A. Starostin on the issue of administrative discretion. Drawing on the theoretical framework proposed by Yu. P.
S. V. Schepalov
doaj   +1 more source