Results 51 to 60 of about 1,497,472 (306)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The law applied by international administrative tribunals: from autonomy to hierarchy [PDF]
, 2015 This Article examines the law applied by the administrative tribunals of international organizations when resolving disputes between international organizations and international civil servants.
Kryvoi, Yaraslau
core +3 more sources
The norms of administrative law as a form of implementation of public administration
Analytical and Comparative JurisprudenceBeing a systematically implemented activity of state authorities and local self-government, public administration is aimed at regulating social relations, ensuring a stable state and development of social processes in the interests of optimal functioning and development of society and the state. The norms of administrative law play an important role in
openaire +3 more sources
Some Aspects of Legislative Administrative Protection of Electoral Procedure Subjects Rights
Vestnik Omskoj Ûridičeskoj Akademii, 2012 The institute of administrative responsibility is one of the most effective instruments of electoral legislation requirements observance. The article deals with the practice of administrative law norms application analysis.
Dogadin A. O.
doaj
The Legislation on Administrative Offenses: Reform or Modernization
Сибирское юридическое обозрение, 2017 The article examines the state of legislation on administrative offenses. The necessity of modernization, ideas and prospects for the development and adoption of a new codified legal act in the relevant legal sphere is argumented.
Aleksandr G. Avdeiko, Dmitrii A. Gazizov
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Law & PassGlobal governance has evolved beyond traditional state-centric and compliance-based legal frameworks toward more complex and pluralistic systems of regulation.
Karna Biswas Singh +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
To the Question of Administrative Responsibilityfor Vagrancy and Begging
Сибирское юридическое обозрение, 2017 The article deals with the issues of modern administrative and legal regulation of counteraction to such antisocial phenomena as vagrancy and begging.
Oleg A. Dizer
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source