Results 101 to 110 of about 905,337 (351)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Employer Sanctions and the Wages of Mexican Immigrants

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences, 2017
Wage differences between authorized and unauthorized Mexican immigrants can be explained by human capital factors prior to the 1986 passage of employer sanctions, which prohibited knowingly hiring unauthorized aliens.
Peter Brownell
doaj   +1 more source

Administrative Offenses and Legal Sanctions in Accordance with Act no. 254/2008 coll., on the Amendment of Legislation Related to Adoption of Act on Selected Measures Against Legitimisation of Proceeds of Crime and Financing of Terrorism [PDF]

open access: yes
The purpose of this paper is to analyse the current state of affairs of legal regulation which is valid and effective on the territory of the Czech Republic to this date, i.e. the Act No.
Mozdiakova, Michaela
core  

Particular aspects of administrative responsibility for administrative offences in the housing and utility sector [PDF]

open access: yes, 2014
Зозуля, І. В. Деякі питання адміністративної відповідальності за правопорушення в галузі житлово-комунального господарства / І. В. Зозуля, Г. В. Синельникова // Науковий вісник Ужгородського національного університету : Серія: Право.
ORCID: http://orcid.org/0000-0002-3507-0012   +4 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

CONCEPTO Y NATURALEZA DE LAS SANCIONES ADMINISTRATIVAS EN LA DOCTRINA Y JURISPRUDENCIA CHILENA

open access: yesRevista de Derecho (Coquimbo)
Esta investigación tiene por objeto establecer el concepto de sanción administrativa que sigue nuestra doctrina y jurisprudencia nacional. Para tal efecto, el autor analiza la distinción que existe entre estas sanciones, los actos administrativos ...
EDUARDO CORDERO QUINZACARA
doaj   +1 more source

SANKSI ADMINISTRATIF KEPADA PEMBERI KERJA DALAM PENYELENGGARAAN JAMINAN SOSIAL

open access: yesJurnal Idea Hukum, 2016
Labor is the main capital Pancasila community development  because the purpose of manpower development is the people's welfare, therefore the rights of workers must be guaranteed.  The Government of Republic of Indonesia has a commitment to be ...
Sri Wahyu Handayani
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The Logic and Limits of Environmental Criminal Law in the Global Setting: Brazil and the United States--Comparisons, Contrasts, and Questions in Search of a Robust Theory [PDF]

open access: yes, 2011
Strict but arguably unfair and counterproductive systems of criminal environmental law and enforcement exist in both the United States and Brazll in the twenty-first century.
Blomquist, Robert F.
core   +2 more sources

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