Results 81 to 90 of about 263,460 (307)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

LEGAL STATUS AND ACTIVITIES OF BODIES AUTHORISED TO IMPOSE FINANCIAL ADMINISTRATIVE SANCTIONS

Baltic Journal of Economic Studies
The existence of a system of financial liability measures is a common occurrence in market economies. Despite their considerable motivational potential, financial administrative sanctions constitute a significant interference with human rights ...
Tetiana Kolomoiets, Serhii Kushnir, Ivan Shumeiko   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

The grounds for enforcement of a disciplinary sanctions to security professionals by US Commission on the Securities and Exchange

RUDN Journal of Law, 2010
The article focuses on the analysis of the legal grounds for enforcement of disciplinary sanctions to security professionals in the U.S. For this purpose it is considered an appropriate legal acts which are the basis of an administrative legal mechanism ...
S A Kapustin
doaj  

Directions for Improving Administrative Legislation in the Sphere of State Security

Bulletin of Kharkiv National University of Internal Affairs
The article is devoted to the analysis of the problems of applying the norms of the Code of Ukraine on Administrative Offenses in the sphere of state security under martial law.
S. F. Konstantinov
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Administrative Offenses and Legal Sanctions in Accordance with Act no. 254/2008 coll., on the Amendment of Legislation Related to Adoption of Act on Selected Measures Against Legitimisation of Proceeds of Crime and Financing of Terrorism [PDF]

The purpose of this paper is to analyse the current state of affairs of legal regulation which is valid and effective on the territory of the Czech Republic to this date, i.e. the Act No.
Mozdiakova, Michaela
core  

Pengaruh Sosialisasi Perpajakan, Sanksi Administrasi dan Tingkat Pemahaman Wajib Pajak terhadap Tingkat Kepatuhan Wajib Pajak Orang Pribadi dalam Memenuhi Kewajibannya (Studi Pph Pasal 21 pada Kpp Pratama Singsosari) [PDF]

, 2016
Taxation not an easy job, in addition to the active role of the tax authorities, awareness and willingness Taxpayer are also very important in the conduct of the process of tax collection. The purpose of this research is to find the effect of between the
Suryadi, I. (Imam)
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

CONCEPTO Y NATURALEZA DE LAS SANCIONES ADMINISTRATIVAS EN LA DOCTRINA Y JURISPRUDENCIA CHILENA

Revista de Derecho (Coquimbo)
Esta investigación tiene por objeto establecer el concepto de sanción administrativa que sigue nuestra doctrina y jurisprudencia nacional. Para tal efecto, el autor analiza la distinción que existe entre estas sanciones, los actos administrativos ...
EDUARDO CORDERO QUINZACARA
doaj   +1 more source