Results 91 to 100 of about 443,616 (316)

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Urine pH and ammonium paediatric reference intervals in first morning spot urine

Advances in Laboratory Medicine
Urinary acidification plays a crucial role in acid-base homeostasis, its evaluation being necessary in the differential diagnosis of metabolic acidosis. The practical limitations of the functional tests required to confirm an acidification disorder point
Díaz-Anadón Lucas Ramón, Rodríguez Julián, Ordóñez-Álvarez Flor Ángel, Gil-Peña Helena, Pons-Belda Óscar David, Cardo Leire   +5 more
doaj   +1 more source

Self perception domains and resilience:wich relation during adolescence

, 2008
The term resilience has been variously used to describe the capacity for successful adaptation to a changing environment and the character of hardiness and invulnerability (Ramanaiah, Sharpe, & Byravan, 1999).
SESTITO, LAURA, MENNA, PALMA
core  

"As soon as you trust yourself, you will know how to live" (Goethe). Protective and mediator factors for internalizing disorders in early and mid-adolescence [PDF]

, 2013
Adolescence is often considered as a period of changes and challenges, during which youth are at particular risk for developing psychological disorders (Lee & Bukowski, 2012; Verona, Javdani, & Sprague, 2011).
Delvecchio, Elisa
core  

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Body, image, and digital technology in adolescence and contemporary youth culture

Frontiers in Psychology
The physical, psychological and social changes that occur during adolescence constitute a physiological crisis that is necessary for development and growth.
Francesco Demaria, Maria Pontillo, Cristina Di Vincenzo, Domenica Bellantoni, Italo Pretelli, Stefano Vicari, Stefano Vicari   +6 more
doaj   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Understanding suicidality in adolescents and young adults at clinical high risk for psychosis: a narrative review on risk factors and clinical insights

Frontiers in Psychiatry
The prodromal stage of psychosis, referred to as the Clinical High Risk (CHR) phase, represents a critical period of heightened vulnerability to suicidality.
Maria Pontillo, Cristina Di Vincenzo, Michelangelo Di Luzio, Francesco Demaria, Barbara D’Aiello, Ilaria Bertoncini, Massimo Apicella, Milena Labonia, Gino Maglio, Roberto Averna, Stefano Vicari, Stefano Vicari   +11 more
doaj   +1 more source

Impact of intrapartum and postnatal antibiotics on the gut microbiome and emergence of antimicrobial resistance in infants

Scientific Reports, 2019
Altogether, 20–30% of women receive intrapartum antibiotic prophylaxis (IAP) to prevent sepsis in infants and 2–5% of newborn infants receive antibiotics due to suspected sepsis.
Terhi Tapiainen, Pirjo Koivusaari, Lauren Brinkac, Hernan A. Lorenzi, Jarmo Salo, Marjo Renko, Hannele Pruikkonen, Tytti Pokka, Weizhong Li, Karen Nelson, Anna Maria Pirttilä, Mysore V. Tejesvi   +11 more
doaj   +1 more source

The quality of parent/child relationships in adolescence is associated with poor adult psychosocial adjustment

, 2013
This study used data gathered over the course of a New Zealand longitudinal study (N = 924) to examine the relationships between measures of parental bonding and attachment in adolescence (age 15-16) and later personal adjustment (major depression ...
David M. Fergusson, Horwood, L. John, Fergusson, David M., Alessandra Raudino, L. John Horwood, Raudino, Alessandra   +5 more
core   +1 more source