Results 131 to 140 of about 1,062,201 (314)

The mediating role of maternal inflammation on associations between first-trimester plasticizer exposure and personal-social and language in infants

Ecotoxicology and Environmental Safety
Background: Maternal exposure to bisphenol A (BPA) or phthalates (PAEs) increases inflammation and the risk of neurodevelopmental disorders in offspring. However, limited epidemiological studies have examined the neurodevelopmental effects of co-exposure
Penghong Li, Wenjuan Xiong, Jia Dong, Yu Han, Tingkai Cui, Zhiyi Qu, Wei Xi, Wei Dai, Shanshan Cui, Xin Zhang   +9 more
doaj   +1 more source

Race and Household Income are Associated with Disease Outcomes in Pediatric Patients with ANCA‐associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, Accepted Article.
Objectives Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric anti‐neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race/ethnicity and household income are associated with severe AAV disease and renal outcomes among ...
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

Advanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu, Philippa J. Karoly, Sina Mansour L., Artemio Soto‐Breceda, Levin Kuhlmann, Mark J. Cook, David B. Grayden   +6 more
wiley   +1 more source

Social conditioning for the self-harm behaviour in adolescence

, 2020
Remus Runcan, Bogdan Nadolu
openalex   +2 more sources

Six-year trends in problematic social media use prevalence and sociodemographic predictors in German adolescents (2019–2024)

Computers in Human Behavior Reports
Research on problematic social media use (PSMU) in adolescents is expanding rapidly, yet heterogeneous definitions and limited population-level data hinder accurate assessment of prevalence trends.
H. Wiedemann, D. Lüdecke, R. Thomasius, K. Paschke   +3 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Changes in Body Mass Index and Prevalence of Varicoceles during Adolescence

, 2007
Jae Il Shin, Jae Seung Lee
openalex   +2 more sources