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Adoptive T-Cell Therapy of Cancer
Hematology/Oncology Clinics of North America, 2006Adoptive therapy involves the transfer of ex vivo expanded immune effector cells to patients as a means of augmenting the antitumor immune response. In general, this transfer is accomplished by harvesting cells from the peripheral blood, tumor sites, or draining lymph nodes and expanding effector cells in a specific or nonspecific fashion for adoptive ...
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Adoptive T-Cell Therapy in Sarcomas
Current Oncology ReportsTo summarise and evaluate the latest adoptive T-cell therapies in sarcomas, focusing on therapeutic targets, efficacy, safety, and limitations.An increasing number of clinical trials are investigating adoptive T-cell therapies in sarcomas, most targeting NY-ESO-1 and MAGE-A4 through engineered T-cell receptors (TCR-T). The FDA approval of afamitresgene
Monika, Kucharczyk +3 more
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Adoptive Cell Therapy for Melanoma
2018Melanoma is a highly immunogenic cancer, and along with the combination of poor clinical outcomes and treatments with limited efficacy, these attributes have made metastatic melanoma an ideal platform to study immune-based therapies. Adoptive cell therapy (ACT) is as a highly effective personalized cancer treatment, utilizing the natural effector ...
Jane Mills +2 more
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Role and Potential of Different T Helper Cell Subsets in Adoptive Cell Therapy
Cancers, 2023Sebastian Kobold +2 more
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Adoptive NK Cell Therapy: A Promising Treatment Prospect for Metastatic Melanoma
Cancers, 2021Jan Spanholtz +2 more
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Adoptive T Cell Therapy for Solid Tumors: Pathway to Personalized Standard of Care
Cells, 2021Shuyang Qin +2 more
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Adoptive Cell Therapy Targeting Neoantigens: A Frontier for Cancer Research
Frontiers in Immunology, 2020Yu J Cao, Wang Zhidong
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