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Physics‐Grounded Materials Artificial Intelligence for Reliable Materials Discovery
Physics‐Grounded Materials AI (PhysMat AI) integrates physical priors, descriptors, constraints, verification, and data infrastructure into a unified full‐stack framework, enabling reliable, interpretable, and autonomous AI‐driven materials discovery.
Yuhang Wang +3 more
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Electrically Induced Phase Transition and Synaptic Functionality in MoTe2/Graphene Memristors
An electrically induced reversible 2H ↔ 1T′ phase transition is demonstrated in a vertical Au/Ti/MoTe2/graphene memristor with a laterally contacted graphene electrode. Resistive switching proceeds through a compositionally invariant amorphous/2H ↔ amorphous/1T′ transformation, in which a self‐formed amorphous MoTe2 interfacial region is proposed to ...
Chien‐Hua Wang +7 more
wiley +1 more source
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Adoptive cell transfer in autoimmune hepatitis
Expert Review of Gastroenterology and Hepatology, 2015Adoptive cell transfer is an intervention in which autologous immune cells that have been expanded ex vivo are re-introduced to mitigate a pathological process. Tregs, mesenchymal stromal cells, dendritic cells, macrophages and myeloid-derived suppressor cells have been transferred in diverse immune-mediated diseases, and Tregs have been the focus of ...
Albert J Czaja
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Adoptive transfer of T-cell immunity
Trends in Immunology, 2002Abstract Allogeneic transplantation is the most successful form of T-cell-based cancer immunotherapy to date. However, a major complication of allogeneic transplantation remains the occurrence of graft-versus-host disease (GVHD). Two recent developments might lead to procedures for the induction of strong tumor-specific T-cell immunity without these ...
Helmut W. Kessels +2 more
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Adoptive T‐cell transfer in cancer immunotherapy
Adoptive T‐cell therapy has definite clinical benefit in relapsed leukaemia after allogeneic transplant and in Epstein–Barr virus‐associated post‐transplant lymphoproliferative disease. However, the majority of tumour targets are weakly immunogenic self‐antigens and success has been limited in part by inadequate persistence and expansion of transferred
Tey, Siok-Keen +2 more
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Adoptive Transfer Immunization of Mice
Cold Spring Harbor Protocols, 2021This procedure is designed to enrich and expand antibody-forming cells for use in generating monoclonal antibodies. Gamma-irradiation is used to wipe out the immune system in a recipient animal, after which spleen cells that have reverted to memory cells are obtained from syngeneic donor animals and transferred to the irradiated animal, allowing the ...
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Adoptive transfer of immunodiabetes in guinea pig
Acta Diabetologica Latina, 1974Inoculation of lymph node or spleen cells from diabetic guinea pigs producing precipitating anti-insulin antibodies produced signs of immunodiabetes in young guinea pigs with cyclophosphamide-suppressed immunological reactivity. Blood sugar increased on day 5 after the cell transfer and distinct B-cell degranulation in the islets of Langerhans was ...
L, Korcáková, M, Titlbach, K, Nouza
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Adoptive Transfer of Immunity to Plasmodium berghei
The Journal of Protozoology, 1969SYNOPSIS. Immunity to P. berghei in rats was transferred adoptively with spleen cells but not with bone marrow cells, thymus cells, peripheral lymph node cells or thoracic duct lymphocytes from immune donors. The parasite multiplies at the same rate in control and protected rats but when about 10% of host red cells are infected the number of infected ...
J A, Roberts, P, Tracey-Patte
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2019
Lymphocytes are an important component of inflammatory bowel disease (IBD) pathogenesis. T cells in particular are potent inducers of inflammation in this disease as well as recurrent players in chronic lesion formation. Here we describe a method for adoptive transfer colitis in mice, which serves as a T cell-based model of inflammatory bowel disease ...
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Lymphocytes are an important component of inflammatory bowel disease (IBD) pathogenesis. T cells in particular are potent inducers of inflammation in this disease as well as recurrent players in chronic lesion formation. Here we describe a method for adoptive transfer colitis in mice, which serves as a T cell-based model of inflammatory bowel disease ...
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Adoptive cell transfer therapy for melanoma
Experimental Dermatology, 2022AbstractAdoptive cell transfer (ACT) of tumor‐infiltrating lymphocytes (TILs) for melanoma is an example of the most successful cancer immune therapy. It achieves a durable complete response about ~20% of patients, and they might be cured. However, the ratio of patients with durable benefits is not high, and its complicated procedure prevents its ...
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