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Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology.
Physiological Reviews, 2008F. Malavasi +7 more
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ADP-Ribosyl Cyclases - A Family of cADPR and NAADP Metabolizing Enzymes
2002ADP-ribosyl cyclase cyclizes NAD to produce cyclic ADP-ribose (cADPR) and releases nicotinamide in the process [1]. It is a ubiquitous enzyme widely present in animal cells [1, 2] and has even been identified in Euglena, a protozoan [4]. The first cyclase purified was from Aplysia ovotestis [1, 5].
Hon Cheung Lee +2 more
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ADP-ribosyl Cyclase and CD38 Catalyze the Synthesis of a Calcium-mobilizing Metabolite from NADP+(*)
Journal of Biological Chemistry, 1995R. Aarhus +4 more
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Intermediates along the NAD+ cyclisation reaction pathway of ADP-ribosyl cyclase
2011Calcium is a ubiquitous, versatile intracellular signal regulating numerous cellular processes [1]. The versatility of Ca2+ signalling emerges from the use of an extensive repertoire of signalling components known as a Ca2+ signalling toolkit that can be assembled in combinations to create signals with different spatial and temporal profiles ...
Zhang, L +4 more
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Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation
Nature Reviews Molecular Cell Biology, 2013Karla L H Feijs +2 more
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