Results 1 to 10 of about 58,391 (264)

CD38 in Neurodegeneration and Neuroinflammation [PDF]

Cells, 2020
Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Damien Toulorge
exaly   +5 more sources

Roles of CD38 in the Immune Response to Infection

Cells, 2020
CD38 is a multifunctional protein widely expressed in cells from the immune system and as a soluble form in biological fluids. CD38 expression is up-regulated by an array of inflammatory mediators, and it is frequently used as a cell activation marker ...
Estibaliz Glaría, Annabel Valledor, Valledor Annabel F   +2 more
exaly   +3 more sources

Assessment of miR-150-5 p as diagnostic and prognostic markers of B- chronic Lymphocytic Leukemia in chronic hepatitis C [PDF]

African Journal of Gastroenterology and Hepatology, 2023
Aims: the current study aimed to investigate the role of miR-150-5 p expression as a diagnostic and prognostic marker of B- CLL among Egyptian patients with chronic hepatitis C and its impact on risk stratification and response to therapy.Patients ...
Nearmeen Rashad, sameh Soliman, Ahmed Obaya, Abdelmonem Elshamy, Amira El helaly, Marwa Hussien, Ahmed Gomaa   +6 more
doaj   +1 more source

Decrease of CD38 expression is linked to increase of solitary plasmacytoma pathological grade: a single institution experience from China

Frontiers in Bioscience-Landmark, 2022
Introduction: Solitary plasmacytoma (SP) is a rare plasma cell disorder characterized by localized neoplastic proliferation of monoclonal plasma cell. Due to its rarity, further understanding of the spectrum of its clinicopathologic features is needed ...
Yueying Li, Jianchun Guo, Chunxiu Yang, Jian Xu, Pei Meng, Shu-Yuan Xiao   +5 more
doaj   +1 more source

CD38 (CD38 molecule) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
Review on CD38 (CD38 molecule), with data on DNA, on the protein encoded, and where the gene is implicated.
Deaglio, S, Vaisitti, T
openaire   +2 more sources

Evaluation of Relationship between CD38 Expression and Gleason Score in Prostatic Carcinoma [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Prostate cancer is the most prevalent non-cutaneous malignancy in men. The Gleason grading system is an important prognostic factor in prostatic carcinoma.
Mohsen Besharati Rad, Mohammadreza Jalali Nadoushan   +1 more
doaj  

Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies [PDF]

Iranian Journal of Immunology, 2023
Background: CD38 is highly expressed on multiple myeloma (MM) cells and has been successfully targeted by different target therapy methods. This molecule is a critical prognostic marker in both diffuse large B-cell lymphoma and chronic lymphocytic ...
Maryam Asadi, Razie Kiani, Vahid Razban, Seyed Faraji, Amirhossein Ahmadi, Jafar Fallahi, Amin Ramezani, Nasrollah Erfani   +7 more
doaj   +1 more source

Immune Phenotype and Functionality of Mtb-Specific T-Cells in HIV/TB Co-Infected Patients on Antiretroviral Treatment

Pathogens, 2020
The performance of host blood-based biomarkers for tuberculosis (TB) in HIV-infected patients on antiretroviral therapy (ART) has not been fully assessed.
Lucy Mupfumi, Cheleka A.M. Mpande, Tim Reid, Sikhulile Moyo, Sanghyuk S. Shin, Nicola Zetola, Tuelo Mogashoa, Rosemary M. Musonda, Ishmael Kasvosve, Thomas J. Scriba, Elisa Nemes, Simani Gaseitsiwe   +11 more
doaj   +1 more source

Jujuboside a improved energy metabolism in senescent H9c2 cells injured by ischemia, hypoxia, and reperfusion through the CD38/Silent mating type information regulation 2 homolog 3 signaling pathway

World Journal of Traditional Chinese Medicine, 2023
Objective: This study explored the myocardial protection role of Jujuboside A through an ischemia–hypoxia–reperfusion (IHR) model. Materials and Methods: H9c2 cells were induced by D-galactose (D-gal) and IHR to establish an aging and IHR model.
Yi-Ran Hu, Hui-Yan Qu, Jia-Ying Guo, Tao Yang, Hua Zhou   +4 more
doaj   +1 more source

Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)

Cells, 2020
The NAD-hydrolyzing ecto-enzyme CD38 is overexpressed by multiple myeloma and other hematological malignancies. We recently generated CD38-specific nanobodies, single immunoglobulin variable domains derived from heavy-chain antibodies naturally occurring
Julia Hambach, Kristoffer Riecken, Sophia Cichutek, Kerstin Schütze, Birte Albrecht, Katharina Petry, Jana Larissa Röckendorf, Natalie Baum, Nicolaus Kröger, Timon Hansen, Gunter Schuch, Friedrich Haag, Gerhard Adam, Boris Fehse, Peter Bannas, Friedrich Koch-Nolte   +15 more
doaj   +1 more source