Results 21 to 30 of about 71,533 (257)

Double CD38–/CD138– negative multiple myeloma

open access: yesHematology/Oncology and Stem Cell Therapy, 2017
The standard diagnosis of multiple myeloma by flow cytometry is based on selection of population of CD38+/CD138+ positives cells. As the result treatment with proteasome inhibitors, CD138 may be underexpressed on atypical plasma cells.
Vitaliy Mykytiv   +2 more
doaj   +1 more source

CD38 (CD38 molecule) [PDF]

open access: yes, 2012
Review on CD38 (CD38 molecule), with data on DNA, on the protein encoded, and where the gene is ...
Deaglio, S, Vaisitti, T
core   +1 more source

IMMUNOHISTOCHEMICAL STUDY OF PROTEINS PROX1, CD133 AND CD38 IN GLIOBLASTOMAS OF THE VENTRICULARSUBVENTRICULAR ZONE AND THEIR EFFECT ON THE LIFE EXPECTANCY OF PATIENTS

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2020
Introduction. Glioblastoma (GBM) is one of the most malignant tumors. Currently, treatment options for GBM are limited, and patient survival rates over the past decades have not changed significantly.The objective of the study was a comparative study of ...
B. E. Galkovsky   +6 more
doaj   +1 more source

Design, synthesis and biological characterization of novel inhibitors of CD38 [PDF]

open access: yes, 2011
Human CD38 is a novel multi-functional protein that acts not only as an antigen for B-lymphocyte activation, but also as an enzyme catalyzing the synthesis of a Ca 2+ messenger molecule, cyclic ADP-ribose, from NAD +.
Sun, Shuang-Yong   +44 more
core   +1 more source

Immune signature profiling identified predictive and prognostic factors for esophageal squamous cell carcinoma

open access: yesOncoImmunology, 2017
Understanding interactions between tumor and the host immune system holds great promise to uncover biomarkers for targeted therapies and clinical outcomes.
Yuan Li   +9 more
doaj   +1 more source

Clinical findings and immunophenotypic profile of plasma cell leukemia: a retrospective study in a comprehensive cancer center in Turkey

open access: yesMedicine Science, 2021
Plasma cell leukemia (PCL) is a rare (1-2 %) aggressive plasma cell dyscrasia (PCD) with a poor prognosis and characterized by the presence of more than 20% circulating plasma cells (PCs).
Nurgul Ozcan   +7 more
doaj   +1 more source

Современные представления о роли CD38 в патогенезе бронхиальной астмы [PDF]

open access: yes, 2013
Current view on a role of CD38 for pathogenesis of bronchial asthma.Современные представления о роли CD38 в патогенезе бронхиальной ...
I. V. Demko   +9 more
core   +1 more source

One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates with Autism Spectrum Disorder in a Japanese Population

open access: yesDiseases, 2020
The transient receptor potential melastatin 2 (TRPM2) is a non-specific cation channel, resulting in Ca2+ influx at warm temperatures from 34 °C to 47 °C, thus including the body temperature range in mammals.
Naila Al Mahmuda   +6 more
doaj   +1 more source

Cluster of Differentiation 38 Protein Significantly Adds to the Prognostic Value of Cytogenetic Risk in Patients with Acute Myeloid Leukemia

open access: yesOman Medical Journal, 2023
Objectives: There is some controversy regarding the clinical significance of cluster of differentiation 38 (CD38) protein in acute myeloid leukemia (AML).
Waiel M. A. AlKahiry   +2 more
doaj   +1 more source

The Many Facets of CD38 in Lymphoma: From Tumor–Microenvironment Cell Interactions to Acquired Resistance to Immunotherapy

open access: yesCells, 2020
The CD38 antigen is expressed in several hematological malignancies, and the anti-CD38 monoclonal antibodies Daratumumab and Isatuximab have an established role in the therapy of multiple myeloma.
Eleonora Calabretta   +1 more
doaj   +1 more source

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