Results 21 to 30 of about 71,533 (257)
Double CD38–/CD138– negative multiple myeloma
The standard diagnosis of multiple myeloma by flow cytometry is based on selection of population of CD38+/CD138+ positives cells. As the result treatment with proteasome inhibitors, CD138 may be underexpressed on atypical plasma cells.
Vitaliy Mykytiv +2 more
doaj +1 more source
Review on CD38 (CD38 molecule), with data on DNA, on the protein encoded, and where the gene is ...
Deaglio, S, Vaisitti, T
core +1 more source
Introduction. Glioblastoma (GBM) is one of the most malignant tumors. Currently, treatment options for GBM are limited, and patient survival rates over the past decades have not changed significantly.The objective of the study was a comparative study of ...
B. E. Galkovsky +6 more
doaj +1 more source
Design, synthesis and biological characterization of novel inhibitors of CD38 [PDF]
Human CD38 is a novel multi-functional protein that acts not only as an antigen for B-lymphocyte activation, but also as an enzyme catalyzing the synthesis of a Ca 2+ messenger molecule, cyclic ADP-ribose, from NAD +.
Sun, Shuang-Yong +44 more
core +1 more source
Understanding interactions between tumor and the host immune system holds great promise to uncover biomarkers for targeted therapies and clinical outcomes.
Yuan Li +9 more
doaj +1 more source
Plasma cell leukemia (PCL) is a rare (1-2 %) aggressive plasma cell dyscrasia (PCD) with a poor prognosis and characterized by the presence of more than 20% circulating plasma cells (PCs).
Nurgul Ozcan +7 more
doaj +1 more source
Современные представления о роли CD38 в патогенезе бронхиальной астмы [PDF]
Current view on a role of CD38 for pathogenesis of bronchial asthma.Современные представления о роли CD38 в патогенезе бронхиальной ...
I. V. Demko +9 more
core +1 more source
The transient receptor potential melastatin 2 (TRPM2) is a non-specific cation channel, resulting in Ca2+ influx at warm temperatures from 34 °C to 47 °C, thus including the body temperature range in mammals.
Naila Al Mahmuda +6 more
doaj +1 more source
Objectives: There is some controversy regarding the clinical significance of cluster of differentiation 38 (CD38) protein in acute myeloid leukemia (AML).
Waiel M. A. AlKahiry +2 more
doaj +1 more source
The CD38 antigen is expressed in several hematological malignancies, and the anti-CD38 monoclonal antibodies Daratumumab and Isatuximab have an established role in the therapy of multiple myeloma.
Eleonora Calabretta +1 more
doaj +1 more source

