Results 11 to 20 of about 58,391 (264)
HIV Research & Clinical Practice, 2021 Objectives: MicroRNA-155 (miR-155) regulates activation of T cells. However, its relationship with T-cell immune activation level in human immunodeficiency virus (HIV) patients remains unclear.
Zhenghao Zhang +5 more
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Biomedical Papers, 2021 Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
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Anti CD38 monoclonal antibodies for multiple myeloma treatment
Human Vaccines & Immunotherapeutics, 2022 CD38 is a transmembrane glycoprotein with ectoenzymatic activity and is highly and uniformly expressed on multiple myeloma (MM) cells. CD38 is expressed also at relatively low levels on normal lymphoid and myeloid cells, and in some tissues of non ...
Alessandro Gozzetti +6 more
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Сибирский научный медицинский журнал, 2021 The aim of the study was to assess the level of NAD+ in the brain of mice treated with beta-amyloid (Aβ), as well as to determine the activity of ADP-ribosyl cyclase/CD38 and the number of CD38-immunopositive neurons, astrocytes and endothelial cells ...
A. A. Semenova +4 more
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Клиническая онкогематология, 2022 Background. Plasmablastic lymphoma (PBL) is a rare variant of large B-cell lymphoma. This disease is usually associated with HIV infection and is predominantly identified in male patients. Tumor lesion is typically localized in oral cavity.
Maiya Valerevna Firsova +3 more
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Indian Journal of Medical and Paediatric Oncology, 2020 Multiple myeloma is a proliferative disorder of plasma cells in the bone marrow with excessive monoclonal protein production. Despite the evolution of multiple drugs and management strategies including maintenance and autologous stem cell transplantation,
Vishnu Gopal, Biswajit Dubashi
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The role of CD38 in HIV infection [PDF]
AIDS Research and Therapy, 2021 AbstractThe widely-expressed molecule CD38 is a single-stranded type II transmembrane glycoprotein that is mainly involved in regulating the differentiation and activation state of the cell. CD38 has broad and complex functions, including enzymatic activity, intercellular signal transduction, cell activation, cytokine production, receptor function and ...
Liqi Lu +4 more
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CD38, CD157, and RAGE as Molecular Determinants for Social Behavior
Cells, 2019 Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knockout mice. Single-
Haruhiro Higashida +22 more
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Biology Open, 2021 The organic anion transporter Adenosine triphosphate binding cassette subfamily C member 1 (ABCC1), also known as MRP1, has been demonstrated in murine models of Alzheimer's disease (AD) to export amyloid beta (Abeta) from the endothelial cells of the ...
Wayne M. Jepsen +7 more
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Double CD38–/CD138– negative multiple myeloma
Hematology/Oncology and Stem Cell Therapy, 2017 The standard diagnosis of multiple myeloma by flow cytometry is based on selection of population of CD38+/CD138+ positives cells. As the result treatment with proteasome inhibitors, CD138 may be underexpressed on atypical plasma cells.
Vitaliy Mykytiv +2 more
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