Chronic endometritis and recurrent implantation failure: a narrative review of clinical relevance and diagnostic challenges [PDF]
Reproduction and FertilityChronic endometritis (CE) is a localized inflammatory disorder of the endometrium characterized by plasma cell infiltration, most often identified by CD138 immunostaining.
Pavel Yakovlev +4 more
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Double CD38–/CD138– negative multiple myeloma
Hematology/Oncology and Stem Cell Therapy, 2017 The standard diagnosis of multiple myeloma by flow cytometry is based on selection of population of CD38+/CD138+ positives cells. As the result treatment with proteasome inhibitors, CD138 may be underexpressed on atypical plasma cells.
Vitaliy Mykytiv +2 more
doaj +3 more sources
Resolving the renal microenvironment: a 5-plex immunofluorescence workflow to quantify B-lineage cells in FFPE lupus nephritis biopsies [PDF]
Frontiers in ImmunologyAccurate identification and spatial enumeration of B lineage cells in formalin-fixed, paraffin-embedded (FFPE) lupus nephritis (LN) kidney tissue is critical for understanding disease pathogenesis and CD20-directed therapeutic responses.
Caleb Chan +5 more
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A shift from membranous and stromal syndecan‐1 (CD138) expression to cytoplasmic CD138 expression is associated with poor prognosis in breast cancer [PDF]
Molecular Carcinogenesis, 2019 AbstractSyndecan‐1 (CD138) is a transmembrane proteoglycan expressed in normal and malignant tissues. It is of interest because of a possible prognostic effect in tumors and as a target for Indatuximab, a monoclonal antibody coupled to a cytotoxic agent.
Franziska Buescheck +2 more
exaly +3 more sources
CD138 (Syndecan-1) Expression in Bone-Forming Tumors [PDF]
American Journal of Clinical Pathology, 2012 CD138 (syndecan-1), a cell surface proteoglycan, is sensitive and specific for plasmacytic differentiation in hematologic disorders. Expression of CD138 has been observed in a majority of epithelial neoplasms and, rarely, soft tissue tumors. However, its expression in bone tumors has not been evaluated.
Vishnu Reddy +2 more
exaly +3 more sources
The impact of CD138 plasma cell severity on IVF-ET outcomes in women with untreated chronic endometritis: a systematic review and meta-analysis [PDF]
BMC Pregnancy and ChildbirthObjective To evaluate the impact of untreated chronic endometritis (CE) on in vitro fertilization (IVF) outcomes, with a specific focus on the differential effects of embryo transfer protocols and CE severity (stratified by CD138-positive plasma cell ...
Jingwen Kong +4 more
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Frontiers in EndocrinologyObjectiveThis study was conducted to determine the influence of the number of CD138+ cells in the proliferative endometrium on pregnancy outcomes.MethodsThis retrospective cohort study was conducted from January to August 2018.
Ruochun Lian, Li Yuye
exaly +3 more sources
Accuracy of office hysteroscopy in the diagnosis of chronic endometritis
Clinical and Experimental Obstetrics & Gynecology, 2022 Background: To test the accuracy of office hysteroscopy in the diagnosis of chronic endometritis (CE) as compared to histopathological diagnosis. Methods: This prospective cohort study was conducted in a private hospital from July 2018 to January 2020 ...
Mohamed Elmahdy Abdel Moneim +3 more
doaj +1 more source
Medicine Science, 2021 Plasma cell leukemia (PCL) is a rare (1-2 %) aggressive plasma cell dyscrasia (PCD) with a poor prognosis and characterized by the presence of more than 20% circulating plasma cells (PCs).
Nurgul Ozcan +7 more
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Syndecan-1 (CD138) immunohistochemical expression patterns in lupus nephritis; reflections on different clinicopathological parameters [PDF]
Journal of Nephropathology, 2021 Introduction: Syndecan 1 (SCD1) is a lectin expressed at the surface of renal tubular epithelial cells and plasma cells. In epithelial cells, cell surface syndecan1 is cleaved by inflammation-induced proteases (eg, ADAMTS, MMP), since loss of cell ...
Marwa M Shakweer, Lobna S Shash
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