Results 1 to 10 of about 981 (117)
Double CD38–/CD138– negative multiple myeloma
Hematology/Oncology and Stem Cell Therapy, 2017 The standard diagnosis of multiple myeloma by flow cytometry is based on selection of population of CD38+/CD138+ positives cells. As the result treatment with proteasome inhibitors, CD138 may be underexpressed on atypical plasma cells.
Vitaliy Mykytiv +2 more
doaj +3 more sources
A shift from membranous and stromal syndecan-1 (CD138) expression to cytoplasmic CD138 expression is associated with poor prognosis in breast cancer [PDF]
Molecular Carcinogenesis, 2019 AbstractSyndecan‐1 (CD138) is a transmembrane proteoglycan expressed in normal and malignant tissues. It is of interest because of a possible prognostic effect in tumors and as a target for Indatuximab, a monoclonal antibody coupled to a cytotoxic agent.
Franziska Büscheck +2 more
exaly +3 more sources
CD138 (Syndecan-1) Expression in Bone-Forming Tumors [PDF]
American Journal of Clinical Pathology, 2012 CD138 (syndecan-1), a cell surface proteoglycan, is sensitive and specific for plasmacytic differentiation in hematologic disorders. Expression of CD138 has been observed in a majority of epithelial neoplasms and, rarely, soft tissue tumors. However, its expression in bone tumors has not been evaluated.
Vishnu V B Reddy +2 more
exaly +3 more sources
Accuracy of office hysteroscopy in the diagnosis of chronic endometritis
Clinical and Experimental Obstetrics & Gynecology, 2022 Background: To test the accuracy of office hysteroscopy in the diagnosis of chronic endometritis (CE) as compared to histopathological diagnosis. Methods: This prospective cohort study was conducted in a private hospital from July 2018 to January 2020 ...
Mohamed Elmahdy Abdel Moneim +3 more
doaj +1 more source
Medicine Science, 2021 Plasma cell leukemia (PCL) is a rare (1-2 %) aggressive plasma cell dyscrasia (PCD) with a poor prognosis and characterized by the presence of more than 20% circulating plasma cells (PCs).
Nurgul Ozcan +7 more
doaj +1 more source
Syndecan-1 (CD138) immunohistochemical expression patterns in lupus nephritis; reflections on different clinicopathological parameters [PDF]
Journal of Nephropathology, 2021 Introduction: Syndecan 1 (SCD1) is a lectin expressed at the surface of renal tubular epithelial cells and plasma cells. In epithelial cells, cell surface syndecan1 is cleaved by inflammation-induced proteases (eg, ADAMTS, MMP), since loss of cell ...
Marwa M Shakweer, Lobna S Shash
doaj +1 more source
Comparison of the IHC markers CD138 and CD43 in oral leukoplakia: An original research
Journal of Pharmacy and Bioallied Sciences, 2023 Background: In the clinical practice, one of the most common suspicious lesions that may be potentially malignant is oral leukoplakia. Globally, the rate at which it turns malignant varies.
Anitha Akkaloori +5 more
doaj +1 more source
Syndecan-1 (CD138), Carcinomas and EMT [PDF]
International Journal of Molecular Sciences, 2021 Cell surface proteoglycans are known to be important regulators of many aspects of cell behavior. The principal family of transmembrane proteoglycans is the syndecans, of which there are four in mammals. Syndecan-1 is mostly restricted to epithelia, and bears heparan sulfate chains that are capable of interacting with a large array of polypeptides ...
openaire +4 more sources
CD138− plasma cell myeloma [PDF]
Blood, 2019 ![Figure][1] A 69-year-old man with a history of CD138− plasma cell myeloma (PCM) who received chemotherapy regimens and stem cell transplant presented for bone marrow biopsy, which revealed sheets of atypical plasma cells with abundant amphophilic cytoplasm, occasional binucleation ...
Wen Shuai, Shaoying Li
openaire +2 more sources
BMC Research Notes, 2022 Objective Inflammation is present in many diseases and identification of immune cell infiltration is a common assessment. CD138 (syndecan-1) is a recommended immunohistochemical marker for human plasmacytes although it is also expressed in various ...
David K. Meyerholz +9 more
doaj +1 more source