Results 41 to 50 of about 4,009 (198)

Immunohistochemistry for CD138.

open access: yes, 2014
(A) Plasma cells immunostained by CD138 are detected in the stromal compartment of chronic endometritis. (B) Plasma cells are not detected in the stromal compartment of non-chronic endometritis, although CD138 is also immunostained in the epithelium of ...
Mitsuaki Ishida (523864)   +8 more
core   +1 more source

siRNA knockdown of BACH2 increased CD138 and gp350 expression.

open access: yes, 2023
(A). Western blot analysis of BACH2 protein expression in non-targeting scramble or Bach2 siRNA 24 hours post transfection (B). CD138 MFI in scramble or transfected cells was significantly increased in BACH2 knockdown (C).
Rosemary Rochford (427830)   +2 more
core   +1 more source

Chronic endometritis and recurrent implantation failure: a narrative review of clinical relevance and diagnostic challenges

open access: yesReproduction and Fertility
Chronic endometritis (CE) is a localized inflammatory disorder of the endometrium characterized by plasma cell infiltration, most often identified by CD138 immunostaining.
Pavel Yakovlev   +4 more
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Proliferation of CD138++ and CD138low subpopulations.

open access: yes, 2014
(A) Left: Cell percentage of CD138++ and CD138low RPMI-8226 or NCI-H929 cells in G0-G1, S and G2-M phases. The results are expressed as the means ± SEM of at least three independent experiments.
Patryk Krzeminski (541133)   +11 more
core   +1 more source

Precision Medicine for Chronic Endometritis: Computer-Aided Diagnosis Using Deep Learning Model

open access: yesDiagnostics, 2023
Chronic endometritis (CE) is a localized mucosal infectious and inflammatory disorder marked by infiltration of CD138(+) endometrial stromal plasmacytes (ESPC).
Masaya Mihara   +2 more
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang   +12 more
wiley   +1 more source

Correlation analysis of serum CRK, CD138, and APL with the prognosis of patients with diabetic nephropathy [PDF]

open access: yesJournal of Medical Biochemistry
Background: To explore the relationships between the levels of serum CITRON kinase-related kinase (CRK), syndecan-1 (CD138), and APJ receptor ligand (APL) and renal function and prognosis in patients with diabetic nephropathy. Methods: From November 2023
Chen Yibo, Li Li, Xia Rui
doaj   +1 more source

Cardiovascular Involvement of a CD138-Negative Anaplastic Myeloma: A Diagnostic Dilemma

open access: yesHematology Reports, 2023
Anaplastic myeloma (AM) is an extremely rare and aggressive histological variant of myeloma. It is characterized by extramedullary presentation in the young and has a poor prognosis. It can be a diagnostic challenge when myeloma is not suspected and even more when the immunophenotype is unexpected.
Jui Choudhuri   +5 more
openaire   +3 more sources

CASTOR1 Regulates Humoral Immune Responses and Contributes to the Pathogenesis of Systemic Lupus Erythematosus

open access: yesArthritis &Rheumatology, EarlyView.
Objective CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda   +5 more
wiley   +1 more source

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