Results 51 to 60 of about 4,009 (198)
Telomerase is active and can be inhibited in MM CD138+ and CD138neg cells.
, 2013 (A) Relative telomerase activity in CD138+ plasma cells and CD138neg CSC isolated from MM cell lines. (B) Relative telomerase activity in CD138+ plasma cells and CD19+CD27+ CSC isolated from clinical MM bone marrow samples.
Calvin Harley (362023) +8 more
core +1 more source
Haematologica, 2010 Generation of B and plasma cells involves several organs with a necessary cell trafficking between them. A detailed phenotypic characterization of four circulating B-cell subsets (immature-, naïve-, memory- B-lymphocytes and plasma cells) of 106 healthy adults was realized by multiparametric flow cytometry.
Anouk Caraux +10 more
openaire +4 more sources
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley +1 more source
, 2014 (A) Single parameter histograms illustrating the expression of ALDH in the presence or absence of the ALDH inhibitor DEAB (diethylaminobenzaldehyde) in CD138++ and CD138low subpopulations of the cell lines RPMI-8226, NCI-H929 and MM1S (B) Sorted CD138 ...
Patryk Krzeminski (541133) +11 more
core +1 more source
LONG-LIVED BONE MARROW PLASMA CELLS DURING IMMUNE RESPONSE TO ALPHA (1→3) DEXTRAN
Медицинская иммунология, 2015 Production kinetics and some functional properties of long-lived marrow plasma cells were studied in mice immunized with T-independent type 2 antigens. Alpha (1→3) dextran was used as an antigen for immunization.
I. N. Chernyshova +3 more
doaj +1 more source
Characterization of potential CD138 negative myeloma "stem cells"
Haematologica, 2012 Syndecan-1 is a heparan sulfate proteoglycan expressed by both normal and multiple myeloma (MM) plasma cells. Matsui et al. [1][1] reported the identification of a potential MM “stem cell” resembling less differentiated post germinal center B cells.
Christensen, Jacob H +5 more
openaire +3 more sources
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana +3 more
wiley +1 more source
4-IPP dedifferentiated RPMI 8226 CD138- cells are chemoresistant.
, 2018 A) Sorted CD138+ cells were treated with 60μM 4-IPP for 24 h. Cells were stained for CD138 and PI and sorted to recover viable (PI negative) CD138+ and CD138- cells.
Danielle Joseph (5920667) +2 more
core +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Circulating tumor plasma cells (CTCs) at diagnosis are independent prognostic markers in newly diagnosed multiple myeloma (NDMM). Flow cytometry (FC) enables sensitive and cost‐effective CTC quantification, but prognostic cut‐offs vary across studies.
Elona Saraci +30 more
wiley +1 more source
CD138 expression changes in response to therapy.
, 2013 A. Percentage of CD138+ human myeloma cells measured by flow cytometry in bone aspirates of mice (n = 3), showing a significantly lower percentage of positive cells in both tibias and spine of mice in the two treatment groups than in untreated mice ...
Simon P. Robinson (381028) +6 more
core +1 more source