Results 61 to 70 of about 19,801 (209)

CD138 immunohistochemistry identifies more plasma cells compared with hematoxylin and eosin staining in autoimmune hepatitis. An observational study

Revista de Gastroenterología de México (English Edition)
Introduction: Autoimmune hepatitis (AIH) is associated with periportal infiltration by plasma cells. Plasma cell detection is routinely performed through hematoxylin and eosin (H&E) staining.
A.F. Romano-Munive, C. Moctezuma-Velázquez, J. Sauma-Rodríguez, P. Ramos-Martínez, A. Torre-Delgadillo   +4 more
doaj   +1 more source

Clinical Images: A thorn injury, a sea‐borne culprit, and a tenosynovitis dilemma

Arthritis &Rheumatology, EarlyView.
Jacopo Ciaffi, Francesco Mori, Paolo Sassu, Marco Gambarotti, Alberto Righi, Eleonora Zamparini, Marco Innocenti, Marina Tadolini, Francesco Ursini   +8 more
wiley   +1 more source

La inmunohistoquímica CD138 identifica más células plasmáticas en comparación con tinción hematoxilina-eosina en hepatitis autoinmune. Un estudio observacional

Revista de Gastroenterología de México
Resumen: Introducción: La hepatitis autoinmune (HAI) está asociada con infiltración periportal de células plasmáticas. La detección de células plasmáticas se realiza rutinariamente por medio de tinción hematoxilina-eosina (HE).
A.F. Romano-Munive, C. Moctezuma-Velázquez, J. Sauma-Rodríguez, P. Ramos-Martínez, A. Torre-Delgadillo   +4 more
doaj   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Early screening and post-treatment chronic endometritis in subsequent frozen embryo transfer cycles among women with first implantation failure: a retrospective cohort study

Frontiers in Endocrinology
BackgroundFirst implantation failure (FIF) remains a significant challenge in in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET), and a considerable proportion of affected women subsequently progress to recurrent ...
Longlong Wei, Longlong Wei, Yixuan Zhang, Shuna Wang, Siyue Xu, Weiran Hu, Weiran Hu   +6 more
doaj   +1 more source

Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines.

PLoS ONE, 2014
Despite recent advances in the treatment of multiple myeloma (MM), it remains an incurable disease potentially due to the presence of resistant myeloma cancer stem cells (MM-CSC).
Teresa Paíno, María E Sarasquete, Bruno Paiva, Patryk Krzeminski, Laura San-Segundo, Luis A Corchete, Alba Redondo, Mercedes Garayoa, Ramón García-Sanz, Norma C Gutiérrez, Enrique M Ocio, Jesús F San-Miguel   +11 more
doaj   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

The Journal of Pathology, EarlyView.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi, Irene Torresan, Emilio Francesco Giunta, Sara Bleve, Nicole Brighi, Elisa Tassinari, Sofia Zanuccoli, Maria Concetta Cursano, Cristian Lolli   +8 more
wiley   +1 more source

Extramedullary Plasmacytoma of Base of Tongue: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Identifying extramedullary plasmacytoma originating from the base‐of‐tongue, in order to evaluate its prevalence, characteristics, management, and treatment within the broader spectrum of head and neck extramedullary plasmacytoma.
Ori Cohen Michael, Ameen Biadsee, Firas Kassem, Matan Katz, Osnat Jarchowsky‐Dolberg, Benny Nageris, Tomer Boldes   +6 more
wiley   +1 more source

Profilin 1 induces drug resistance by downregulating CD138 expression via autophagy in multiple myeloma

Discover Oncology
Multiple myeloma (MM), a plasma cell-derived malignant hematological disease, is often treated with bortezomib, a highly effective first-generation proteasome inhibitor. However, resistance to bortezomib is a common occurrence.
Ya Wang, ZiYu Dai, Shengying Xiao, Furen Zeng, YiChen Lu   +4 more
doaj   +1 more source

Phenotypic plasticity in plasma cell myeloma: a CD138-negative case with a rare BRAF G469R mutation [PDF]

Journal of Pathology and Translational Medicine
CD138-negative plasma cell myeloma harboring a BRAF G469R mutation is described in a 76-year-old male presenting with multiple osteolytic lesions. Histologically, the lesion exhibited epithelioid to plasmacytoid morphology with prominent mitotic activity
Sun-Ju Oh, So-Hak Chung
doaj   +1 more source